1.Clinical study of thymalfasin combined with radiotherapy for non-small cell lung cancer
Chinese Journal of Primary Medicine and Pharmacy 2015;(24):3801-3803
Objective To discuss the clinical effect of thymalfasin combined with radiotherapy for non -small cell lung cancer (NSCLC).Methods According to digital table,61 patients with NSCLC were randomly assigned to combined therapy group and radiotherapy group.The control group(radiotherapy group)only used radia-tion therapy.The treatment group(combination group)used thymalfasin combined with radiotherapy.The tumor lesion changes,immune indicators and the quality of life were observed.Results The effective rate of the tumor lesion changes in the treatment group was 83.9%,which in the control group was 76.7%(χ2 =0.725,P >0.05)).The levels of CD +4 ,CD +4 /CD +8 in the treatment group were (49.29 ±4.48)%,(1 .91 ±0.44),which were significantly higher than (33.1 7 ±1 .07)%,(1 .38 ±0.48)in the control group (t =1 4.69,5.34,all P <0.05).The improve-ment rate of digestive tract reaction in the treatment group was 74.2%,the body -weight ratio was 38.7%,the increased rate of KPS(karnofsky performance score)was 64.5%,while those of the control group were 23.3%, 1 3.3%,36.7% (χ2 =5.87,6.1 2,3.87,all P <0.05).Conclusion Compared with the use of radiotherapy only, thymalfasin combined with radiotherapy for NSCLC was more effective for patients in tumor lesion response,cell immu-nity and the quality of life.
2. Modularized teaching program on the clinical research training for pathological residents
Yu SHI ; Tao LUO ; Yangfan LÜ ; Yong LIN ; Zhicheng HE ; Haiqing ZHANG ; Xiaohui YIN ; Rui TANG ; Feng WU ; Weiqi DANG ; Jing YANG ; Yifang PING ; Xiuwu BIAN ; Xiaochu YAN ; Xiaohong YAO
Chinese Journal of Medical Education Research 2019;18(10):1025-1028
To meet the requirement of pathological practice and development, we systematically analyzed the situation of pathological residents training and the importance of initiating the clinical scientific research training. Additionally, we proposed the principle and implementation strategy for clinical scientific research training. According to features of pathological practice, we employed the modularized teaching to divide the training courses into several modules: discussion module for clinical pathology, lecture module for advanced research, and training modules for basic scientific theory, technology and writing skill. With these approaches, the systematic and structured system of standardized residents training is implemented to improve the clinical research ability of pathological residents.