To assess the pharyngeal presentations and the diagnostic value of thyroid SPECT and thyroid fine needle aspiratory biopsy (FNAB) in subacute thyroiditis (SAT) as seen initially in ENT department, 30 patients, during the course of SAT, were examined for pharyngeal symptoms and tested for serum T3, T4 level. The thyroid SPECT imaging or thyroid FNAB were performed. Our results showed that, of the 30 patients, 21 had sore throat of various degrees, and 9 had abnormal sensation of throat. Six were diagnosed as having SAT by only SPECT, in the remaining 24, the final diagnoses was established by SPECT combined with FNAB. Two of them were finally diagnosed as having SAT by trial treatment with oral prednisone. It is concluded that sore throat and abnormal sensation of pharynx are the important presentations of SAT, and thyroid SPECT imaging and thyroid FNAB are valuable in diagnosing SAT.
Diagnosis, Differential ; Pharyngeal Diseases/diagnosis ; Pharyngitis/diagnosis ; Thyroid Gland/*radionuclide imaging ; Thyroiditis, Subacute/*diagnosis ; Thyroiditis, Subacute/radionuclide imaging ; Tomography, Emission-Computed, Single-Photon

Objective:To assess the effect of a course of intravenous dexamethasone on pain after tonsillectomy.Method:Sixty patients who underwent tonsillectomy or adenoidectomy and tonsillectomy were randomly divided into experimental group and control group. Postoperatively, 30 patients in experimental group received anti-inflammatory drug and dexamethasone for 4 days, and the other 30 patients in control group received anti-inflammatory drug and placebo. Degree of postoperative pain was measured with visual analogue scale in the patients more than 12 year old and with Wong-Baker faces pain scale in the patients less than or equal to 12 year old. The measurement was made twice daily for 5 days.Result:During the postoperative period, the scale value was decreasing every day in the all patients.But the value in experimental group was less than that in control group, and the difference was statistically significant (P<0.05).Conclusion:Dexamethasone given in this regime reduces postoperative pain and odynophagia after tonsillectomy.

Kidney damage caused by inappropriate use of some chinese herb drugs are quite common in our country. This review give a brief introduction of those reports concened, which include the most frequently used herb drugs of Aristolochia and their main components, the pharmacokinetic of Aristolochic acid, the different clinical manifestation of chinese herb nephropathy and the possible mechanism of the nephrotoxicity of Aristolochic acid.

To assess the curative effects of different reduction techniques on the dislocation of cricoarytenoid joint caused by intubation, indirect laryngoscope (IL) and direct laryngoscope (DL) were utilized for the closed reduction of the displaced arytenoid under local anesthesia. 23 patients who underwent the reduction for dislocated arytenoid under IL or DL from January 1991 to June 2001 were reviewed. The data were collected on the duration of the laryngeal injury, times of receiving reduction, side-effects after the treatment and the period for voice to return to normal. The relationship between the duration of the laryngeal lesion and the period of the voice rehabilitation was examined. 13 patients received the reduction under IL and 10 patients under DL. Except the times of the reduction, which showed significant difference, no differences were found between IL group and DL group in the course and the period of voice rehabilitation, as well as sore throat after the manipulation. The patients' voice recovery was positively related to their course of disease in both IL and DL group. It is concluded that the recovery of normal voice is obviously affected by the duration of arytenoid dislocation. The reduction under IL is as effective as under DL in the treatment of arytenoid dislocation. Reduction by DL is better suit the patients with long time course of disease.
Arytenoid Cartilage/*injuries ; Dislocations/diagnosis ; Dislocations/*etiology ; Dislocations/therapy ; Intubation, Intratracheal ; Laryngeal Cartilages/*injuries ; Laryngoscopes/adverse effects ; Laryngoscopy/*adverse effects ; Laryngoscopy/methods

Recently, the pharmacological study of Ganoderma spores and active components has be-come a focus of attention in the world. The present reviewis based on the auctorial research on Ganoder-maspores. It involves pharmacological effects of Ganodermaspores and its active components, includingimmunomodulating effect, antitumor activity and its mechanismin vivoandin vitro, liver-protectiveeffect, gastric ulcer preventing effect, serum glucose and blood fat depressing effects, anti-hypoxia andscavenging free redical, etc. The possible problems and their solutions in this research area are also dis-cussed.

Objective To investigate the correlation between infertility and TORCH infections ,analyse the possible influence factors .Methods TORCH infections of 2343 cases of pregnant women and 1356 cases of infertility women were detected by chemi‐luminescence method ,the positive rates of TORCH‐IgM ,IgG were compared .Results RV ,HSV infections of infertility women were higher ,mainly in 30 -34 years group .TORCH infections of infertility women among seasons were of significant difference (P<0 .05) .TORCH infections of infertility women have correlations with schooling levels ,source of family ,and history of expo‐sure to animals (P<0 .05) .Conclusion The less education ,rural aera ,and history of exposure to animals were high risk factors of TORCH infections ,so screening for TORCH infections of infertility women is very necessary .

Objective To study the influence of sufentanil on analgesic effect and hemodynamics during recovery period of general anesthesia in elderly patients.Methods Eighty patients with general anesthesia were randomly divided into 4 groups (20 cases in each group).Ten min before surgery ended patients in each group were intravenous injected different dose of sufentanil:group S1 with sufentanil 0.2 μg/kg,group S2 0.4 μg/kg,group S3 0.6 μg/kg,and group C (control group) with saline 5 ml.The time of spontaneous breath restores,the time of summon opening eyes and extubation,the cases occurred cough,nausea,vomiting during recovery period were recorded and the VRS pain scores and Ramsay score 10 min after extubation were also recorded.Mean arterial pressure (MAP) and the heart rate (HR) were recorded before the anesthesia induction(T0),stopped anesthetic (T1),pre-extubation (T2),5 min and 10 min after extubation (T3 or T4)Results As group S1 and S2 compared with group C,there was no significant difference on the time of spontaneous breath restores,the time of summon opening eyes,and the time of extubation and leaving the operating room (P ＞ 0.05).However,there was significant difference on the time of spontaneous breath restores ((7.3 ± 4.1) min vs (10.2 ± 4.7) min),the time of summon opening eyes ((8.1 ± 3.1) min vs (11.2 ± 3.7)min),the time of extubation ((12.3 ± 3.1) min vs (16.3 ± 5.9) min),and the time of leaving the operating room((21.4 ±3.0)min vs (24.2 ±3.5)min) between the group S3 and group C(P＜0.01 or P ＜0.05)Patients occurred cough in group S1,S2 and S3 were less than those in group C (P ＜0.05),but there was no significant difference on the occurrence of nausea and vomiting between group S1-3 and group C (P ＞ 0.05)There was significant difference on VRS pain score and Ramsav score between group S1-3 and group C(P ＜0.01).MAP and HR were increased in all points of time as compared with T0 (P ＜ 0.05 or P ＜ 0.01).And there was significant difference on MAP and HR between group S1-3 and group C (P ＜ 0.05 or P ＜ 0.01).Conclusion Before the end of anesthesia sufentanil 0.2 ～ 0.4 μg/kg intravenous injection could be able to enhance analgesic effect,stabilize hemodynamics and do not affect regain consciousness in elderly patients.

Objective To determine the content of fructose in radix ophiopogonis cropped in Sichuan and Zhejian, and in extracts of radix ophiopogonis. Methods A HPLC-ELSD method was used for determining the content of fructose. Results The content of fructose in radix ophiopogonis cropped in Sichuan and Zhejiang were 11.32%～19.96% and 3.85%～10.19%, respectively. The contents of fructose in extracts of radix ophiopogonis cropped in Sichuan and Zhejiang were 23.48%～25.82% and 21.39%～ 23.29%, respectively. Conclusion The content of fructose in radix ophiopogonis cropped in Sichuan was higher than that of in Zhejiang. The content of fructose in extracts of radix ophiopogonis cropped in Sichuan was almost the same as that of in Zhejiang.

Objective:To explore if there was a correlation between TNFAIP8 and gastric tumor drug resistance. Methods:We collected 47 cases of neoadjuvant chemotherapy,and detected the expression of TNFAIP8 in their tissues before and after surgery by im-munohistochemistry. Compared the expression of TNFAIP8 between SGC7901 cell and its cisplatin resistance cell SGC7901-DDP by Western blot,and then we used siRNA technology to decreased its expression,continued to test the susceptibility to cisplatin through MTT. Results:The expression of TNFAIP8 between pre-neoadjuvant and after-neoadjuvant had no difference, but the expression of chemotherapy effectiveness was lower than chemotherapy invalidness(P<0. 05);the expression of SGC7901-DDP cell was also higher than SGC7901 cell; the expression of TNFAIP8 decreased apparently through plasmid transfection of SGC7901-DDP cell, MTT test showed the fewer expression of TNFAIP8 could increase the susceptibility to cisplatin(P<0. 05). Conclusion: TNFAIP8 was involved in chemotherapy resistance of gastric carcinoma.

[Objective]To evaluate the results of therapy with knee joint synovectomy or articular irrigation in rheumatoid arthritis.[Method]Thirty-six knees in 32 rheumatoid arthritis patients-according to ARA standard were performed with knee joint synoveetomy and articular irrigation.Twenty-two knees in 20 patients(most in grade Ⅰ)were treated with knee joint cavity irrigation operation combined with intra-articular injection of hyaluronic acid,and 14 knees in 12 cases(most in grade Ⅱ)with knee joint synovectomy,All 32 patients received routine anti-rheumatoid drug therapy preoperatively and postoperatively,and were followed-up for 6 months.All the cases were evaluated by the Lysholm scale.[Result]The early symptoms of all knee joints were improved.The excellent and good result rate of articular irrigation-group was 86.4%,and in synovectomy-group was 85.7%.[Conclusion]Satisfactory results can be obtained through articular irrigation combined with intra-articular rejection of hyaluronic acid and concomitant anti-rheumatoid drug therapy in early-stage of rheonmtoid arthritis,but for mid-stage patients,especially with hyperplasia synovium and deslxoyed cartilage,joint synoveetom should he performed early in order to obtain favoring rehabilitation.