1.Research progress on patella fracture fixation
Aifeng LIU ; Hongbin JIN ; Zhibin WANG
Orthopedic Journal of China 2006;0(02):-
Literatures about patella fracture fixation in recent years are analyzed retrospectively in this paper.Its characteristics and therapeutic purpose are investigated.A series of new type of internal fixations and external fixations are emphasized.
2.Measurement and clinical application of normal plantar pressure
Haijing HUANG ; Zhibin WANG ; Hongbin JIN
Orthopedic Journal of China 2006;0(03):-
[Objective]To develop a mini-pressure-sensor(MPS)for measurement of plantar pressure(PP)and to evaluate its clinical application.[Method]The MPS was installed in the shoes,and computer was used to accumulate and analyze the change of PP in whole walking stage.Pathologic changes of PP in clinical patients were also analyzed by MPS.[Result]In normal walking,the PP of forefoot was 49% of body weight(BW)and of midfoot and heel was totally 51% of BW,but at pathologic state,the equilibrium of walking was dynamically disrapted inducing a pathologic changes of foot bearing.[Conclusion]Self-developed MPS for measuring PP is help for dynamic analysis of normal PP and is valuable to recognize the pathologic distribution of PP in pathological state and to provide a guide for treatment.
4.Inhibitory effects of sinomenine on the activation of nuclear factor-?B and on the degradation of I?B
Xiaokun JIN ; Weidong LI ; Huiling TENG ; Zhibin LIN
Chinese Pharmacological Bulletin 2003;0(07):-
Aim To observe the effect of Sinomenine on the activation of NF-?B and the degradation of its inhibitor I-?B in peritoneal macrophages of BALB/c mice in vitro and provide experimental evidence for further evaluation of the antiinflammatory and antirheumatic effects of Sinomenine. Methods Effect of Sinomenine on the activation of NF-?B p65 in the cells was investigated by using fluorescence-labelling and laser confocal scanning microscopy; Effect of Sinomenine on the degradation of I?B-? was investigated by Western blot. Results SIN (0.25,1.25 mmol?L -1) attenuated the activation of NF-?B p65 in peritoneal macrophages of BALB/c mice induced by LPS in vitro. SIN(0.25,1.25 mmol?L -1) inhibited the degradation of I-?B-? in peritoneal macrophages of BALB/c mice induced by LPS in vitro. Conclusion SIN can partially inhibit the activation of NF-?B p65 and the degradation of I?B-? in peritoneal macrophages of BALB/c mice induced by LPS in vitro.
5.Value of 2D ultrasound and elastic strain ratio in diagnosis of thyroid tumor by fine needle aspiration
Jie ZHANG ; Min WU ; Juan PENG ; Zhibin JIN ; Qiuyue CAO
Chinese Journal of Ultrasonography 2014;23(6):493-496
Objective To evaluate the value of 2D ultrasound and elastic strain ratio (SR) in diagnosis of thyroid nodule by fine needle aspiration (FNA).Methods 196 thyroid nodules were analyzed retrospectively with 2D ultrasound,elastography and FNA results,pathology results as the golden standard.A receiver operating characteristic (ROC) curve was used to identify the best cut-off point of SR.The Logistic regression analysis was used to evaluate the variables effectiveness on age,nodule echo,calcification and SR.Tried to discuss how to use SR before or after US-FNA in diagnosis of thyroid nodule.Results The SR of the malignant nodules group was significantly different from the benign nodules group,and the best cut-off point was 0.5 with sensitivity 91.7%,specificity 90.2 % and accuracy 90.8 %.The Logistic analysis results were SR,age,echo,calcification according to the odds ratio.SR can screened nodules without puncture necessary before FNA,and increase the FNA sensitivity,specificity and accuracy after FNA.Conclusions SR has good application value in diagnosis thyroid malignant tumor.SR can reduce unnecessary FNA and make a supplementary diagnosis of FNA.
6.Construction of Libguides subject service platform
Yan ZHANG ; Jin CHENG ; Xiaoru YANG ; Qun ZHANG ; Lei WANG ; Zhibin YANG
Chinese Journal of Medical Library and Information Science 2014;(12):32-36
The Libguides subject service platform that integrates technologies, resources and service has effectively promoted the subject service in library.Its introduction, construction and achievements in Medical Library of Chinese PLA were described with strategies proposed for improving its problems.
7.The value of elastography in diagnosis of thyroid malignant tumor by fine needle aspiration
Min WU ; Jie ZHANG ; Zhibin JIN ; Jian YANG ; Juan PENG ; Qiuyue CAO
Chinese Journal of Endocrinology and Metabolism 2014;30(4):307-311
Objective To evaluate the value of elastic strain ratio (SR) in ultrasound guided fine needle aspiration (US-FNA) of thyroid nodule.Methods A total of 222 thyroid nodules from 216 patients were reviewed and analyzed by Logistic regression of clinical data,2D ultrasound,and SR.The odds ratios of variables in the equation were compared to assess various variables,especially of SR in the diagnosis.The sensitivity,specificity,and accuracy of the SR method,US-FNA method,and combined method were calculated.Results Three statistically significant features finally entered the Logistic regression model,followed by SR,echo,and age according to the odds ratio.The sensitivity,specificity,and accuracy of the SR method,US-FNA method and combined method were 85.4%,82.1%,83.3% ; 91.5%,82.1%,85.6% ; 97.6%,94.3%,95.5% respectively.Conclusions SR<0.5 is the most important risk factor in differential diagnosis of thyroid malignant nodules from benign nodules.SR raises the sensitivity,specificity,and accuracy of US-FNA method and plays an important role in diagnosing thyroid nodules via US-FNA.
8.Construction of information platform for research and development institutions of foreign miliat ry medical equipments
Fangwei LI ; Xiaoru YANG ; Jin CHENG ; Xiaoyan ZHANG ; Liang YIN ; Zhibin YANG
Chinese Journal of Medical Library and Information Science 2014;(5):8-11
The information was obtained through the open access channels and organized with free markers.The relations in research and development institutions of foreign military medical equipments were determined by analy-zing thecompetitive opponents .The information platform for research and development institutions of foreign mili-tarymedical equipments was constructed using the MVC design model in combination with Web2.0 technology and community concept of resources according to the B/S structure forthe collection, storage, organization, analysis, sharing and evaluation of military medical information resources .
9.Reconstruction of 3D finite-element model of patella and effectiveness analysis
Aifeng LIU ; Jianxiong MA ; Ping WANG ; Hongbin JIN ; Zhibin WANG ; Xinlong MA ; Xin FU ; Yang YANG
International Journal of Biomedical Engineering 2011;34(2):94-97,封3
Objective To build a three-dimension finite-element model of patella and to make a preliminary mechanics analysis on the model.Methods According to the model-building principle of Ansys software which started from point to line to area to volume,a three-dimension finite-element patella model was reconstructed on the basis of the images of spiral CT.Then,loading on the model patella were simulated and the stress magnitude and distribution on the patella were analyzed.Results Finite element analysis of the patella showed that stress concentration zone located in the middle and lower patella,indicating that fracturepredilectionsitesinthelower patellar.TheVon misesstresson thetensionsidewas significantly greater than that on pressure side.Conclusion The established finite element model of the patella can reflect the real geometry of patella treated in clinics.
10.U.S.military syndromic surveillance system ESSENCE:a typical case study
Jin CHENG ; Xiaoru YANG ; Qun ZHANG ; Zhibin YANG ; Fangwei LI ; Zhijing XU ; Tao ZHENG
Military Medical Sciences 2014;(2):112-116,128
Syndromic surveillance , based on non-specific pre-diagnosis and other information , is capable of nearly real-time detection and early warning of potential bioterrorism and emerging infectious threats .Developed countries , led by the U.S., have conducted in-depth and front research in this area while China has just started syndromic surveillance re -search in the exploratory trial stage .The Chinese army is facing an urgent need for syndromic surveillance .This paper makes a case study of foreign military syndromic surveillance practices , typically the U.S.representative system ESSENSE , which was developed by the U .S.Department of Defense and deployed in all military treatment facilities .Some suggestions for the Chinese army are also discussed .