1.An analysis of the prognosis factors in testicular seminoma
Zhibin CHENG ; Jiucheng ZHANG ; Changqing LI
Chinese Journal of Radiation Oncology 1992;0(01):-
Purpose:To analyze the prognostic factors of testicular seminoma.Materials and Methods:133 patients with testicular seminoma histologically proved were treated from October, 1975 to December,1990. Most of them were firstly treated with orchiectomy and minority were treated with orchiectomy plus lymphadenectomy in abdomen cavity. All patients were treated with postoperative radiotherapy and a little part of them were combined with irregular chemotherapy. Results: The overall 5-year survival rates were:92.5(65/70) for stage Ⅰ, 52.6(10/19) for stageⅡ, 25%(4/16) for stage Ⅲ and 22.2%(2/9) for stage Ⅳ. Patients received radiation dose of 20~30Gy gave a five year survival rate of 80% which was much better than those who received radiation dose 30Gy(P
2.The value of Gd-EOB-DTPA enhanced magnetic resonance imaging in the quantitative evaluation of liver function
Lili HUANG ; Zhibin CHENG ; Mei LI ; Yanli JIANG ; Jing ZHANG
Chinese Journal of Hepatobiliary Surgery 2014;20(5):324-327
Objective To explore the value of Gd-EOB-DTPA enhanced magnetic resonance imaging (MRI) in the quantitative evaluation of liver function.Methods Between June 2012 and June 2013,we prospectively included 8 patients with cirrhosis and 6 patients with primary hepatic carcinoma (PHC).The Child-Pugh classification,indocyanine green retention rate at 15 minutes (ICGR15),and Primovist enhanced MR imaging were performed in all the patients.Using the deconvolution method to calculate hepatic extraction fraction (HEF),the correlations between HEF and Child-Pugh and ICGR15 were analyzed.Results For cirrhosis,there was a significant correlation between the HEF and the ICGR15 by the Pearson correlation coefficient (r =-0.971,P < 0.05).For hepatocarcinoma,there was also a significant correlation (r =-0.855,P < 0.05).The average HEF of PHC was 21.80% (14.89% ~ 35.90%).Conclusions The Gd-EOB-DTPA enhanced MRI accurately evaluated liver function quantitatively.It may be used for patients with PHC for preoperative examination.
3.Decreased expression of Foxp3 in patients with allergic rhinitis
Zhonglin MOU ; Zhibin ZHAO ; Huabin LI ; Yenong TAN ; Lei CHENG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(06):-
OBJECTIVE To evaluate the role of forkhead transcription factor p3(Foxp3) in the pathogenesis of allergic rhinitis(AR).METHODS Nasal tissues and peripheral blood mononuclear cells(PBMCs) were obtained from 17 patients with AR and 11 controls.Foxp3 was detected in nasal tissues by immunohistochemisry and real-time reverse transcription polymerase chain reaction(RT-PCR).Foxp3 and CD4+CD25+T cells were evaluated in PBMCs by using ? ow cytometry.RESULTS The numbers of Foxp3+ cells was(44.2?20.5)cells/mm2 and(129.5? 35.6)cells/mm2 in nasal mucosa of two groups(P
4.Selected three-field lymphadenectomy in thoracic middle-lower section esophageal carcinoma
Fuzeng WANG ; Cunshuan CHENG ; Yunfeng CHENG ; Guangqing WEI ; Qingliang WANG ; Zhibin CHENG ; Xiaogang CHENG ; Haiyun GUO
Journal of Chinese Physician 2011;13(1):53-57
Objective To explore the technique and effect of selected three-field lymphadenectomy by left thoracotomy in treatment of thoracic middle or lower section esophageal squamous carcinoma. Methods From Jun. 2005 to Mar. 2009, 213 patients with thoracic middle or lower section of esophageal carcinoma received esophagectomy, bilateral mediastinal lymphadenectomy and pleural membrane resection.Group 1 -5, 7 - 12a, 16al, and 19 were performed to dissect abdominal lymph node and extended thoracic and abdominal lymphadenectomy and only lymph node extraction of mesoesophagus in neck field. Results 14197 lymphatic nodes(LN) were detected in 213 case. The average number of resected LN was 66. 65 ±24. 73. The metastatic lymph node was detected in 105 cases. The metastatic rate was 49.05% (105/213).There were 423 metastatic lymph nodes. The lymph nodes metastasis was 2. 97% (423/14197) of all dissected lymphatic nodes. No remnant carcinoma in the upper and lower cutting edge was found in pathological examination. The operation time ranged from 2. 92 ~ 4. 67 ( 3. 37 ± 0. 42) hours. Blood transfusion during perioperative period was 0 ~ 6u ( 1.08 ± 0. 93 ) u. Perioperative plasma transfusion was 0 ~ 1400( 103.77 ± 184. 89) ml. The hospital-time was 14 ~ 39 ( 17.64 ±4. 12) days. There were no anastomotic leakage and recurrent laryngeal nerve injury. One case died from respiratory failure, the mortality was 0. 04% ( 1/213). Conclusion Surgical approach in the management of left thoracotomy in the sixth intercostals could extend resection of chest-field lymph node dissection, decrease neck field lymph node dissection. Abdomen-field lymph node dissection reached selected D3. The selected lymphadenectomy procedure had the advantages of small traumas and few complications.
5.Construction of Libguides subject service platform
Yan ZHANG ; Jin CHENG ; Xiaoru YANG ; Qun ZHANG ; Lei WANG ; Zhibin YANG
Chinese Journal of Medical Library and Information Science 2014;(12):32-36
The Libguides subject service platform that integrates technologies, resources and service has effectively promoted the subject service in library.Its introduction, construction and achievements in Medical Library of Chinese PLA were described with strategies proposed for improving its problems.
6.U.S.military syndromic surveillance system ESSENCE:a typical case study
Jin CHENG ; Xiaoru YANG ; Qun ZHANG ; Zhibin YANG ; Fangwei LI ; Zhijing XU ; Tao ZHENG
Military Medical Sciences 2014;(2):112-116,128
Syndromic surveillance , based on non-specific pre-diagnosis and other information , is capable of nearly real-time detection and early warning of potential bioterrorism and emerging infectious threats .Developed countries , led by the U.S., have conducted in-depth and front research in this area while China has just started syndromic surveillance re -search in the exploratory trial stage .The Chinese army is facing an urgent need for syndromic surveillance .This paper makes a case study of foreign military syndromic surveillance practices , typically the U.S.representative system ESSENSE , which was developed by the U .S.Department of Defense and deployed in all military treatment facilities .Some suggestions for the Chinese army are also discussed .
7.Subject service in Medical Library of Chinese PLA:Its 3-year practical experiences and prospect
Ting Lü ; Fangwei LI ; Xiaoru YANG ; Jin CHENG ; Xiaoyan ZHANG ; Liang YIN ; Zhibin YANG
Chinese Journal of Medical Library and Information Science 2014;(1):38-41,68
The practical experiences with subject service in Medical Library of Chinese PLA were summarized in terms of the establishment of user information records, accumulation and summation of information, and construc-tion of information platform. Suggestions were put forward for the improvement of subject service in Medical Library of Chinese PLA, such as holding the big information concept in the big data era, using the biomedical data as the target of study, providing various kinds of service, integrating seamless, dynamic and interactive library service into user service. The fact that focus on artificial intelligence, computer, information and coomunication technologies is one of the future directions was pointed out.
8.The application of improved CHQS for mass epidemiology study on hearing impairment
Cheng LIU ; Guangqian XING ; Xia XU ; Zhibin CHEN ; Han ZHOU ; Dengyuan WANG ; Huiqin TIAN ; Xingkuan BU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2010;(1):19-20,24
Objective:To develop and evaluate the improved Chinese hearing questionnaire for school children(CHQS)for mass epidemiology study on hearing impairment in China.Method:Using the probability proportion to size(PPS) method, 8 412 residents were investigated in 40 clusters in Jiangsu province with the WHO ear diseases and hearing disorders survey protocol.87.9% of the residents aged 7 years and over answered the questionnaire and accepted the pure tone audiometry.Result:The prevalence of hearing impairment was 12.9% by the questionnaire. Compared with golden standard(pure tone audiometry), Sen=58.5%, Spe=96.7%, PV+=78.9%, PV-=91.7%, overall accuracy=90.0% . The sensitivity for women was higher than men.Conclusion:The questionnaire produced high efficiency and specificity values.It could be used in mass hearing screening, particularly in remote and rural area, although the sensitivity was as low as most questionnaires.
9.Investigation on influence factors of gernal surgeon growth
Youcheng ZHANG ; Man WU ; Zhibin CHENG ; Xuan GAO ; Shuying ZHAO ; Yong ZHANG
Chinese Journal of Medical Education Research 2016;15(6):596-599
Objective To investigate the general surgeon growth time, and to probe into the factors affecting the surgeon growth. Methods 72 surgeons who worked more than 15 years in the field of general surgery in 12 hospitals of Gansu Province were investigated, focusing on education, resident rotation train-ing, teachers' qualification, refresher training, the frequency of intra-hospital technical exchange, and scale of hospital employed. SPSS 18.0 statistical software was applied to analyze the data. t test was used in com-parison between groups, and multiple groups were compared by using single factor analysis of variance. Results The surgeon growth time was (9.84±1.51) years averagely. In the process of growing up, the growth time of the general surgeons who experienced hospital resident rotated training, refresher training, intra-hos-pital technical exchange was significantly shorter than that of no-related-experienced surgeons. The higher the education, the higher the quality of the teachers and the higher the level of medical institutions, the shorter the doctor's growth time. Conclusion In the same medical institutions, the resident rotated training, the teacher's qualification, higher hospital training, and the frequency of intra-hospital technical exchange have the positive function to the surgeon's general growth, so in making young doctor training plan we should consider the value of the above-mentioned factors.
10.Construction of information platform for research and development institutions of foreign miliat ry medical equipments
Fangwei LI ; Xiaoru YANG ; Jin CHENG ; Xiaoyan ZHANG ; Liang YIN ; Zhibin YANG
Chinese Journal of Medical Library and Information Science 2014;(5):8-11
The information was obtained through the open access channels and organized with free markers.The relations in research and development institutions of foreign military medical equipments were determined by analy-zing thecompetitive opponents .The information platform for research and development institutions of foreign mili-tarymedical equipments was constructed using the MVC design model in combination with Web2.0 technology and community concept of resources according to the B/S structure forthe collection, storage, organization, analysis, sharing and evaluation of military medical information resources .