Objective To observe and analyze the short-term clinical effect of Zhenwu decoction combined with taxol and carboplatin (TC) in treatment of post-operative patients with ovarian cancer.Methods The clinical data of eighty-six post-operative patients with ovarian cancer from June 2014 to June 2015 in our hospital were retrospective analyzed, and randomly divided into control group and treatment group, 43 cases in each group.The control group received TC treatment and treatment group received Zhenwu decoction on the basis of control group with two courses, 21d of one course. The clinical effect were compared between two groups post-treatment.Results After treatment, the total efficacy in treatment group was higher than that in control group (88.37%vs.65.11%;χ2 =6.515,P<0.05), the improvement rate of life quality was higher (72.09% vs.27.91%;χ2 =16.790,P<0.05), the stable rate of life quality had no statistical difference (23.26%vs.30.23%;χ2 =0.534,P>0.05), the reducing rate of life quality was lower (4.65%vs.41.86%;χ2 =10.030,P<0.05), the effect of Karnofsky performance score (KPS) was higher (93.02% vs.72.09%;χ2 =6.541, P<0.05), the complication rate was lower (4.65% vs.18.60%;χ2 =4.074,P <0.05).Conclusion The clinical effect of Zhenwu decoction combined with taxol and carboplatin (TC) in treatment of post-operative patients with ovarian cancer was satisfying, which could improve prognosis and improve survival rate.

Objective To investigate the clinical value of ureteroscopy combined with ESWL for the treatment of ureteral stone.Methods From October 2005 to June 2007,a total of 256 patients with ureteral stones were treated in our hospital.The calculus in the middle and lower ureter were removed by ureteroscopy,while the stones in the upper ureter was treated by ESWL.For the cases that failed ureteroscopy or those who had residual stones after the treatment,ESWL was performed as a supplement.ResultsIn the patients with lower ureteral stones,the one-stage cure rate was 98.2%(167/170),while in those with middle and upper ureteral calculi,the rate was 89.2%(50/56) and 73.3%(22/30) respectively.Three patients developed perforation of the ureter during the surgery,and one had mucosal injury of the ureter.One case was converted to open surgery because of perforation of the ureter resulted from ureteral twist.Twelve patients were failed ureteroscopy or had residual stones,and received ESWL as the second-stage treatment,11(91.7%) of them were cured afterwards.Conclusions Ureteroscopy is effective for middle and lower ureteral stones.For the cases failed the operation or have residual calculi,ESWL is a good choice.

Sleep and memory are the basic function of the brain. A large number of studies from both humans and animals experiments have offered a substantive body of evidence supporting that sleep contributes crucially to memory consolidation. The processes of memory consolidation in hippocampus and cortex during sleep was reviewed and the primary cellular and molecular mechanism were briefly introduced.

The left to right shunt rate(F)and the transverse seetional area of ductus arteriosus(A)were calculated by color Doppler flow convergence method in 20 patients with patent ductus arteriosus.The results indicated that the shunt rate(F)was correlated fairly with Qp-Qs,Qp/Qs(measured by pulsed wave Doppler),the pressure gradient(△P)and the diameter of left ventricle(DLV)(r=0.81,0.62,0.69 and 0.53;P＜0.001,0.005,0.001 and 0.01,respectively).The transverse sectional area of ductus arteriosus(A)was also correlated closely with the diameter of ductus arteriosus(Dd)measured directly in two-dimensional view(r=0.81,P＜0.001).The F value of group Qp/Qs≥2:1 was apparently higher than that of group Qp/Qs＜2:1(P＜0.005).The color Doppler flow convergence method can rapidly and exactly evaluate the left to right shunt severity of patent ductus arteriosus.

The shape of regurgitant jets in 30 patients with eccentric mitral regurgitaltoll Showing flow convergence region(FCR)was observed.It was found that the shapes of the jets were allslender and close to left atrial wall.In comparison of the regurgitant volume calculated by pulsed Doppler and regurgitant flow rate by flow convergence with the regurgitant jet area and the ratio 0f the regurgitant area to left atrial area respectively,the results showed that there were poor correlations between them (r=0.59,0.56 and r=0.55,0.57)and good correlation between regurgitant volume determined by Pulsed Doppler and regurgitant flow rate by flow convergence(r=0. 96,P<0.01).When the regurgitant flow rates calculated by flow convergence were same,the regurgitartt jet area and the ratio of the regurgitant jet area to left atrial area of non-eccentric mitral regurgitation were obviously larger than those of eccentric mitral regurgitation.The results indicated that the regurgitant jet area and the ratio of the regurgitant jet area to left atrial area underestimated the severity of eccentric mitral regurgitation apparently and that flow convergence region could be used to assess the seVerItY 0f eccentric mitral regurgitation accurately.

[Objective]To determine whether discectomy resulted in improvement in low back pain(LBP)associated with lumbar disc herniation. [Method]Two hundred and one consecutive single-level lumbar discectomy were followed up,one hundred patients underwent microendoscopic discectomy(MED group) and 101 patients were treated with conventional open discectomy(COP group).Outcomes were assessed using Visual Analog Scale(VAS) and patient satisfaction.The changes in LBP were compared between the MED group and COP group.The effects of severity of low back pain before surgery on the improvement of back and leg pain were also determined.The mean duration of follow-up was 45 months.[Result]The mean VAS leg pain significantly decreased from 70.02?15.80 before operation to 7.73?12.13 at final follow-up.A significant improvement was also noted in LBP,the mean VAS LBP score was 43.61?26.18 before surgery and 16.89?14.73 at the time of final follow-up.The important improvement in LBP and leg pain was seen in 70.1%～78.1% and 97.0% patients respectively.Improvements in back pain and leg pain were correlated(r= 0.1656,P=0.0304).The rate of important improvement of low back pain was greater in MED group than in COP group.The rate of important improvement in LBP was similar in the patients of a preponderance of LBP,a preponderance leg pain and an equivalence of LBP and leg pain,the patients with a preponderance of LBP showed a lower rate of important improvement in leg pain than the others.[Conclusion]Discectomy for relief of sciatica of lumbar disc herniation provides effective relief of LBP.The MED is more likely effective as a surgery way to relief LBP.Furthermore,it certified that the severe LBP maybe a negatively predictive factor for the follow-up outcome of leg pain.

Objective To evaluate the feasibility and accuracy of real-time three-dimensional transesophageal echocardiography(TEE) in assessment of left atrial appendage(LAA) function. Methods Forty-two atrial fibrillation patients underwent real-time three-dimensional TEE. LAA ejection fraction based on two-dimensional area measurements(EFA-2D), three-dimensional area measurements(EFA-3D) and three-dimensional volume measurements(EFv-3D) were calculated and related to LAA peak empty velocity (PEV). The variability within observer and interobserver were tested. Results EFA-2D was significantly higher than EFA-3D[(62.84 ± 17.27)% vs (45.39 ± 16.58)%, P = 0.000] and EFv-3D [( 62.84 ±17.27) % vs (48.35 ± 19.37) %, P = 0.001 ], whereas EFA-3D and EFv-3D had no significant difference ( P = 0.158). In a simple linear correlation,the degree of association between EFv-3D and PEV was higher as between EFA-3D and PEV ( r = 0.662 vs 0.604,both P ＜0.05). No significant correlation was observed between EFA-2D and PEV ( r = 0.529, P = 0.130). Variabilities within observer and interobserver were no significant differences by the three methods( P ＞0.05). Conclusions LAA ejection fraction calculation by real-time three-dimensional TEE is feasible and more accurate than by 2D TEE.

Objective With a newly developed ultrasoundbased technique named as echo tracking,to determine the carotid stiffness and compliance in familial hypercholesterolemia(FH) patients.Methods The study population included 8 FH patients with 3 male and 4 female at a mean age of((17.22)?(5.69)) years and 7 normal controls. With the echo tracking technique,the quantitative parameters of Ep,? and the arterial compliance(AC) were detected.Results Ep,? and AC of the subtotal FH patients were higher than that of controls,the statistical significance was found in ? of both common carotid arteries,Ep of right common artery and AC of left artery in two groups.Conclusions The echo tracking technique may be a promising modality for noninvasive estimation of the atherosclerotic proceeding in FH patients.

Objective To observe the shape and the hemodynamic changes of the left heart after transcatheter closure of atrial septal defects(ASD) using Amplatzer occluder.Methods Sixty-five subjects with secondum ASD underwent transthoracic echocardiography(TTE) at pre-operation,48～72 h post-operation and follow-up performed more than 3 months after operation in 45 patients.The dimension of ASD,the parameters of the pulse-wave Doppler spectrums of the blood flow at the aotic valves and inlet of the left ventricle were recorded.At each position,systolic,early diastolic velocities and intervals were measured,the mitral annular movement spectrum was acquired at the lateral site of mitral annulus in the apical four-chamber view,Tei index and Tei_(TDI) index were derived from these parameters.Results All the patients had been implanted one Amplatzer occluder under the guide of echocardiography successfully.The preload of the left ventricular volume in the end of the diastolic period was increased and the low hemodynamic situation of the left heart and systemic circulation were corrected after the operation immediately.Accordingly,at 48～72 h after the operation,the end diastolic diameter,the stroke volume and the ejection fraction of the left ventricle were significantly improved continuously.However,the movement of the posterior wall decreased significantly at 48～72 h post-operation.The peak velocity of systolic period and the early diastolic velocities of the left ventricle were increased,but the ejection time had no changes follow-up.The systolic function of the left ventricle highlighted,the whole diastolic time prolonged after the 3 months of the operation.Tei index,Tei_(TDI) index and the heart rate had no difference between pre-and post-operation.Conclusions The anatomic deformation was corrected by transcatheter closure of ASD with Amplatzer occluder,the pre-load of left ventricular increased and had significant effect on the morphology and hemodynamic situation quickly,the left ventricular systolic and the diastolic function improved.The pre-load change of left heart had no effect on heart rate.Tei index and Tei_(TDI) index were independent of the pre-load and present the heart-self function.