1.Survey of HIV infection among STD outpatients in Xinjiang
Yonghui DONG ; Qi ZHI ; Yan JIN
Chinese Journal of AIDS & STD 2006;0(04):-
Objective To investigate HIV infection via sex in Xinjiang,in order to provide guidance for the formulation of strategy to control and prevent sexual transmission of HIV.Methods Vistiors to 15 STD clinics in 5 cities of Xinjiang were asked to take blood and to be tested for HIV and RPR.At the same time,medical workers carried out the designed investigation.Result A total of 2 499 STD outpatients were investigated,among whom 28 samples were confirmed to be HIV positive and 145 samples were RPR positive;the infection rate was 1.12% and 5.80%,respectively,with male being 0.97% and female being 1.37% in the positive samples.The Han nationality had 8 HIV positive samples,and the Uygur nationality had 20 positive samples,with the positive rate being 0.44% and 3.49%,respectively.The Han nationality had 66 and the uygur had 79 in RPR positive samples,the positive rate being 3.66% and 13.79%,respectively.In 212 cases of syphilis 4 samples were HIV positive,the infection rate being 1.89%;in 420 cases of GU 10 samples were HIV positive,the infection rate being 2.38%.Our behavioral surveys found that those who 100% used condoms in their sex activities were free of HIV infection,while those who never used condoms had a high ratee of infection,up to 2.77%.Conclusion Sex transmission is becoming an important route of spreading HIV infection in Xinjiang,and therefore it is essential to strengthen serological and behavioral surveillance for high risk population and implement effective interventions for them.
2.Evaluation of early diagnosis and treatment of cancer.
Zhi-wei DONG ; You-lin QIAO ; Gui-qi WANG
Chinese Journal of Oncology 2012;34(8):637-640
3.Adhesion and Proliferation of Bone Mesenchymal Stem Cells with PLGA-[ASP-PEG] Polymer Scaffolds
Zhi-Xia DUAN ; Qi-Xin ZHENG ; Xiao-Dong GUO ;
China Biotechnology 2006;0(12):-
Objectives: To investigate the effects of adhesion and proliferation of bone mesenchymal stem cells (BMSCs) in the surface of lactic acid/glycolic acid/asparagic acid-co-polyethylene glycol PLGA-[ASP-PEG] tri-block polymer scaffolds, try to find a new biomaterial to induce seed cells in vitro for bone tissue engineering. Methods: Modified PLGA with polyethylene glycol (PEG) and asparagic acid (ASP) that has many ligands, and synthesis PLGA-[ASP-PEG] polymer material. BMSCs were cultured in PLGA-[ASP-PEG] polymer material and PLGA used as control group. Through precipitation method, MTT assay and total cellular protein detection to test the adhersion and proliferation of BMSCs. Scanning electron microscope is used to observe cells appearance. Results: BMSCs on the surface of PLGA-[ASP-PEG] polymer scaffolds are adherention to the culture flask, the number of cells is much higher than PLGA’s. The precipitation method suggest that adhesion and proliferation of BMSCs on the surface of PLGA-[ASP-PEG] is much higher than the control group(P
4.Effect of dexmedetomidine and midazolam on hemodynamics and sedation in patients with nasal intubation
Xue XU ; Xiang QI ; Zhi LIANG ; Xiaoqing ZHANG ; Zhenming DONG
Chinese Journal of Postgraduates of Medicine 2012;35(6):1-3
Objective To study the effect of dexmedetomidine and midazolam on hemodynamics and sedation in patients with nasal intubation.Methods Forty patients whose ASA grade Ⅰ-Ⅱ and anticipated difficult airway were randomly divided into dexmedetomidine group(group D,20 cases)and midazolam group(group M,20 cases)according to the admission number.In group D,dexmedetomidine 1 μ g/kg were constant speed pumped in 10 minutes.In group M,midazolam 0.03 mg/kg were intravenous injected.Then nasal intubation were carried.Systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial blood pressure(MAP),heart rate(HR),pulse oxygen saturation(SpO2),Ramsay sedation score,rate-pressure product(RPP),tip perfusion index(TPI)were recorded and compared before anesthesia (T0),fiberoptic bronchoscope pass by later nostril(T1),to spy on epiglottis(T2),intubation succeed(T3),after intubation 1 minute(T4)and after intubation 3 minutes(T5).Airway score and postoperative visit were evaluated.Results SBP,DBP,MAP,HR,RPP in group M were significantly higher at T1-T3 than those at T0 (P<0.05),and were significantly higher than those in group D at the same time(P< 0.05).There was no significant difference in group D(P > 0.05).Ramsay sedation score and TPI at T1-T3 in group M were significantly lower than those at To(P <0.05).Ramsay sedation score and TPI at T1-T5 in group D were significantly higher than those at T0(P < 0.05),and were significantly higher than those in group M at the same time(P < 0.05).The rate of airway score 1 score and intubation satisfaction in group D were significantly higher than those in group M[100%(20/20)vs.30%(6/20),90%(18/20)vs.50%(10/20)](P< 0.05).The rate of throat ache in group D was significantly lower than that in group M[5%(1/20)vs.35%(7/20)](P <0.05).Conclusions For difficult airway patients with nasal intubation during dexmedetomidine infusion,hemodynamics is stable and sedation is satisfied.
5.Analysis of surgical treatment in 388 cases with nodular Hashimoto's disease
Jian-Ping HANG ; Dong MENG ; Qi-Zhong GAO ; Li-Qi LI ; Zhi-Hui XIE ;
Chinese Journal of Endocrinology and Metabolism 1986;0(03):-
Objective To investigate surgical opportunity and suitable treatment approach in nodular Hashimoto's disease.Methods An analysis was performed in 388 pathologically confirmed cases with nodular Hashimoto's disease and other thyroid-related diseases.All the cases were involved with surgical treatment due to thyroid nodules from June,1995 to Dec,2005.Results Among the above-mentioned cases,64 cases (16.5%) were Hashimoto's disease with the presence of thyroid cancer,190 (48.9%) nodular thyroid tumor,94 (24.2%) thyroid adenoma,7 (1.8%) hyperthyroidism,the rest (8.5%) simple Hashimoto's disease.Prior to 2000, among 106 cases of Hashimoto's disease there were 15 cases accompanied by thyroid cancer.Since 2001,282 cases of Hashimoto's disease were dealt surgically,49 of which had thyroid cancer.Compared to the period from 1995 to 2000,the complication of Hashimoto's disease and thyroid cancer has been sharply increasing during the recent five years (P
6.Effects of simvastatin on the expression of RANTES in patients with hypercholesterolemia
Yong-Hong LI ; Zhi-Ming GE ; Zhi-Qiang LI ; Shan-Lang CAI ; Yi AN ; Qi-Xin WANG ; Guo-Xiong DONG ;
Chinese Journal of Emergency Medicine 2006;0(12):-
6.24 mmol/L) and sixty healthy persons in the health center of our hospital were investigated as hyperhpidemia group (Hyperlipidemias) and control group (Controls) respectively.Hyperlipidemias were given simvastatin 20 mg?d~(-1) for twelve weeks (Statins).Blood samples of ulnar vein were extracted from Statins at the end of twelve weeks as well as Controls and Hyperhpidemias at the beginning of the experiment. Blood serum,plasma and mononuclearcell were extracted and stored at a refrigerator of-80℃.The level of plasma angiotensinⅡwas detected by the method of radioimmunity.While the expression of RANTES mRNA and protein on mononuclearcell were assessed by real time reverse transcription polymerse chain reaction and Western blot respectively.Results①The plasma angiotensinⅡof Hyperlipidemias was higher than that of Controls [(92.13?22.03) vs (50.85?12.12),P
7.Isolation and Characterization of Endophytic Microorganisms in Glaycyrrhiza inflat Bat. from Xinjiang
Su-Qin SONG ; Mahmut OTKUR ; Zhi-Dong ZHANG ; Qi-Yong TANG ;
Microbiology 1992;0(05):-
The present investigation was undertaken in order to select the surface-sterilization technique most efficient for eliminating epiphytes, to document endophytes of healthy tissues from Glaycyrrhiza inflat Bat. in Xinjiang. Surface sterilization with 5% commercial solution of sodium hypochlorite for 5 minutes was reaffirmed as adequate for removing epiphytes on licorice roots. From the 151 segments incubated, 149 bacterial isolates and 2 fungal isolates were obtained. From all the isolates, Bacterial isolates were identified by VITEK-AMS. Part of Bacteria were identified in 13 different genus. Fungal species were characterized as Penicillium sp. and Fusarium sp.with microscope.
8.Comparison of Rhizosphere Microorganisms Between Fusarium Wilt Resistant and Susceptible Watermelon
Juan-Li LEI ; Wei-Song SHOU ; Wen-Qi DONG ; Zhi-Hao XU ;
Microbiology 2008;0(07):-
In this paper, the number of rhizosphere and non-rhizosphere microbial organisms of fusarium wilt resistant and susceptible watermelon under soil culture and soilless substrate culture was studied by traditional culture methods. The results showed that, the number of rhizoshpere microorganisms was significantly higher than non-rhizosphere, and the number was changed with the stage of watermelon grow, the number was the lowest in seedling stage and increased with the watermelon grow, and achieved highest at the flowering and fruiting stage, decreased with the watermelon ageing. The fusarium wilt resistant of watermelon was correspondence with number of rhizosphere bacteria; the number of rhizosphere bacteria of resistant watermelon was higher than that of susceptible watermelon in each stage under soil culture and soilless culture. The fusarium wilt resistant of watermelon is no correspondence with number of rhizosphere fungi and actinomycete. The number of non-rhizosphere microbial organisms was changed in a small range in the whole growing stage. The non-rhizosphere bacteria have no significant change in the whole stage under soil culture and increased quickly under soilless substrate culture and decreased at the later stage. The non-rhizosphere fungi and actinomycete reached highest at the later stage under soil culture or soilless sub-strate culture.
9.Research on Change of Inflammatory Factors in Obstructive Sleep Apnea Syndrome with Hypertension
Zhi LIU ; Qi HUA ; Dong-Bao LI ; Jing TAN ; Hong-Xu ZHU ;
Chinese Journal of Hypertension 2006;0(10):-
20 beats/ h);⑤ normal control group(n=20):healthy person without OSAS or hypertension.The serum level of IL-6, sCD40L,hsCRP,sICAM-1,VACM-1 are determined by ELISA method.Results The serum level of IL-6, sCD40L,hsCRP,sICAM-1,VCAM-1 in patients of OSAS alone group or HT alone group is higher than that of normal control group;whereas,the serum level of IL-6,sCD40L,hsCRP,sICAM-1,VCAM-1 in patients with hy- pertension co-existed OSAS are furthermore higher than that of OSAS alone group,hypertension alone group(P
10.Comparison of Rhizosphere Bacteria Diversity Between Fusarium Wilt Resistant and Susceptible Watermelon
Juan-Li LEI ; Wei-Song SHOU ; Wen-Qi DONG ; Zhi-Hao XU ; Cheng-Hao ZHANG ;
Microbiology 2008;0(12):-
The traditional culture methods and the molecular biology methods were used to study the rhizosphere bacterial diversity between fusarium wilt resistant and susceptible watermelon. The results showed that the diversity and the equality of cultured rhizosphere bacteria of resistant watermelon were higher than those of the susceptible watermelon. The reason was that the cultured rhizosphere bacterial di- versity index H′ and 1/D of the resistant watermelon were higher than those of the susceptible watermelon and that the cultured rhizosphere bacterial equality index E of the resistant watermelon were higher than those of the susceptible watermelon. The dominant cultured bacterial genotypes were different between re- sistant and susceptible watermelon. The genotype 1 is the dominant genotype of resistant watermelon, con- sists 51.1%. The genotype 7 is the dominant genotype of susceptible watermelon, consists 58.7%.