2.Application value of multifunctional dynamic fiat panel X-ray detector in intravenous pyelography
Huijun HU ; Jiaoxia CHEN ; Yueyao CHEN ; Zhi TAN ; Dandan YUN
Chinese Journal of Postgraduates of Medicine 2014;37(30):42-43
Objective To investigate the application value of multifunctional dynamic flat panel X-ray detector in intravenous pyelography.Methods Total 540 patients with intravenous pyelography were divided into multifunctional dynamic flat panel X-ray detector group (300 cases) and conventional flat panel X-ray detector group (240 cases) by random digits table method.Image quality,radiation dosage and examination time were analyzed and compared between the two groups.Results There was no statistical difference between the two groups in image quality (P > 0.05).The examination time and radiation dosage was (25.5 ± 8.2) min and (12.5 ± 6.8) mAs respectively in multifunctional dynamic flat panel X-ray detector group and (39.2 ± 12.1) min and (23.6 ± 7.6) mAs in conventional flat panel X-ray detector group.The differences had statistical significance (P < 0.01).Conclusions Multifunctional dynamic flat panel X-ray detector in intravenous pyelography can provide lower radiation dose,shorter examination time and higher image quality.It has obvious advantages in urography.
4.Clinical analysis of treatment outcome for 559 patients with endometrial cancer
Zhi SUN ; Hua- WANG ; Yun CHEN ; Yu-Lan REN ;
China Oncology 2000;0(06):-
Background and purpose:With the recognition of prognostic factors and application of surgical- pathological staging,the treatment strategy of endometrial cancer has greatly changed.In this study,we investigated the treatment strategy,survival rate and prognostic factors of endometrial cancer.Methods:Five hundred and fifty-nine patients of endometrial cancer underwent primary surgical treatment from January 1996 to December 2006 in Cancer Hospital,Fudan University.The clinicopathologic parameters and prognosis were analyzed retrospectively.Results: Patients were followed up with the median period 36 months,25 cases experienced local relapse,24 cases were found to have distant metastases.The 3-year overall survival(OS)was 88.7%,3-year and 5-year disease free survival(DFS) was 82.7% and 80.9%.The 3-year overall survival(OS)were 95.5% in stageⅠ,95.3% in stageⅡ,75.9% in stageⅢand 32.4% in stageⅣrespectively(P
5.Wolffian Adnexal Tumor:Report of One Case.
Zhi-Qiang WANG ; Jin-Yun KAI ; Hua-Ying CHEN
Acta Academiae Medicinae Sinicae 2020;42(4):570-572
This article reports a patient who suffered from Wolffian adnexal tumor.We also briefly elucidate the pathogenesis,clinicopathological features,diagnosis,differentiation,and treatment of Wolffian adnexal tumor,with an attempt to increase the awareness of the disease and reduce misdiagnosis.
Adenoma
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Adnexal Diseases
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Female
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Humans
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Immunohistochemistry
;
Wolffian Ducts
6.A rapid Screening Procedure for Identification of Succinate Producing Anaerobic Strains
She CHEN ; Xiao-Bei ZHAN ; Yun CHEN ; Zhi-Yong ZHENG ; Li-Min ZHANG ;
Microbiology 1992;0(02):-
In order to obtain an efficient screening procedure for identification of succinate producing anaerobic strains,a semi-quantitative paper chromatography method was developed. Lactic acid and acetic acid were identified as the main byproducts in the process of succinate production by the high performance liquid chromatography (HPLC).Succinic acid was completely separated from the byproducts of lactic acid and acetic acid in the same broth developed by paper chromatography.The content of succinic acid was calculated by a semi-quantitative method.The results showed that paper chromatography was a simple and cost effective method that could be utilized to screen anaerobic strains producing succinic acid.
7.Effects of heparin coating on intimal hyperplasia in implanted decellularized xenografts
wei-wei, CAI ; yong-bing, CHEN ; ya-hong, WANG ; yun, TANG ; chang-zhi, CHEN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(11):-
Objective To investigate the effects of heparin coating on intimal hyperplasia in implanted decellularized xenografts.Methods The resected canie carotid arteries were decellularized,and heparin coating was partially performed.Eighteen rabbits were divided into non-heparin-coated group(n=9)and heparin-coated group(n=9).During implantation,only the left carotid between the anastomotic stoma was ligated.Doppler ultrasonography was performed 1,3 and 12 weeks post-implantation to measure the luminal diameter,and the hemodynamic parameters such as PSV,RI and PI were calculated.All animals were sacrificed,histological observations were conducted at 12 weeks post-implantation,and I/(I+ M)was calculated.Results Except for 1 week post-implantation in the ligated side,the luminal diameters in non-heparin -coated group were significantly smaller than that of pre-implantation.Besides,those of the non-ligated side at each time points were significantly smaller than the ligated side(P
8.Analysis of phacovitrectomy with internal limiting membrane peeling to treat foveoschisis without macular hole in ultra-high myopia
Zhi-Yong, WU ; Yi, YAO ; Xin-Yi, LIU ; Yun-Hua, MIN ; Zhi-Yi, CHEN ; Li-Rong, HAN
International Eye Science 2017;17(6):1181-1183
AIM: To analyze the results of phacovitrectomy with internal limiting membrane(ILM) peeling to treat foveoschisis in ultra-high myopia.METHODS: Totally 32 eyes of 32 ultra-high myopia patients with foveoschisis were selected retrospectively.The preoperative refractive errors ranged from-12.00D to-20.00D with the mean of-15.78±2.16D.The best corrected visiual acuity(BCVA) were converted to LogMAR acuity, and the average BCVA was 4.1±0.4.Conventional phacovitrectomy with ILM peeling by ICG dying were performed.Gas tamponade were performed to end the operation.The BCVA and the foveoschisis cavity were observed by 1-9mo after the surgery, with the mean of 4.5mo.RESULTS: The foveoschisis cavity of 30 eyes were healed with BCVA increased and visual distortion alleviated distinctly (94%)(t=-7.91, P<0.05).CONCLUSION: Phacovitrectomy with ILM peeling is useful in treating foveoschisis in ultra-high myopia with visual function preserving.
9.Pathologic changes of sinoatrial node P cells and cardiac myocytes in experimental fluorosis.
Wei YI ; Yan-ni YU ; Chen-yun ZHANG ; An-zhi WEN ; Yi-guo LONG ; Hua ZHANG ; Zhi-zhong GUAN
Chinese Journal of Pathology 2010;39(4):264-265
Animals
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Female
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Fluorosis, Dental
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blood
;
etiology
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Glutathione Peroxidase
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blood
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Male
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Malondialdehyde
;
blood
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Myocytes, Cardiac
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pathology
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ultrastructure
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Random Allocation
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Rats
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Rats, Sprague-Dawley
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Sinoatrial Node
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pathology
;
ultrastructure
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Sodium Fluoride
;
poisoning
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Superoxide Dismutase
;
blood
10.Clinical observation of bevacizumab (avastin) for treating age - related macular degeneration
Zhi-Guang, DUAN ; Li-Yun, YU ; Yun-Qin, JIA ; Ni, MO ; Yin-Chao, CHEN ; Tao, TAO ; Min, LIU ; Shi-Xue, PU ; Ming-Zhi, LI
International Eye Science 2014;(6):1016-1019
AIM: To evaluate the safety and efficacy of intravitreal bevacizumab ( avastin ) injection in patients with exudative age related macular degeneration ( AMD) .
METHODS: The records of patients treated with intravitreal injection of 1. 75mg bevacizumab for AMD were retrospectively reviewed. All patients were evaluated by complete ophthalmic examination, optical coherence tomography and fundus fluorescein and/or indocyanine green angiography. Observation was made on the best corrected visual acuity ( BCVA) , intraocular pressure, and the changes of lens, vitreous, central retinal thickness (CFT) and total macular volume (TMV), at 1d, 3d, 7d, 1mo and 6mo after the treatment and then compared with those of pre - operation. Repeated treatment with intravitreous bevacizumab occurred if there were signs of persistent or recurrent exudation. And all cases were followed up at least 6mo. An intravitreal injection of bevacizumab (1. 75mg) was given once every 6wk.
RESULTS:All 50 eyes of 48 patients with the average of 58±20. 46 years old were included. The mean baseline of BCVA and CFT were 0. 82±0. 53, and 364. 97±151. 83μm respectively. Although there was no significant decrease in mean CFT and TMV one week after the injection, the mean BCVA had significant improvement. At the last visit of 9. 7mo follow - up, BCVA, CRT and TMV showed significant improvements over baseline values. BCVA was improved by at least two lines in 32 eyes (64%),remained stabilization in 18 eyes (36%) at the last visit. A total of 98 injections were performed and the average number of injections was 1. 98 for each eye in the group. About 50%of re - injections gained at least two lines of vision improvement one week postoperatively. There were no serious adverse events during the treatment.
CONCLUSION: Intravitreal bevacizumab ( avastin ) injection for managing CNV due to age-related macular degeneration is safe and few side effects. Intravitreal avastin associated with improvement in visual acuity ( VA ) , which can reduce macular edema and choroidal neovascularization leakage. But a prolonged treatment effect needs further observation.