1.Clinical research on application of adjustable sutures in glaucoma filtering operation
International Eye Science 2014;(10):1868-1870
AIM:To discuss the application effect of adjustable sutures in glaucoma filtering operation after trabecular resection.
METHODS: Seventy-eight cases ( 101 eyes ) suffered from glaucoma were randomly divided into two groups, observation group and control group. Thirty-nine cases ( 51 eyes ) in the observation group underwent trabeculectomy with adjustable sutures, the control group (39 cases, 50 eyes) only adopted trabeculectomy.RESULTS: Compared Preoperative IOP in two groups, the difference was not statistically significant (P>0. 05). After 6mo, IOP were decreased compared with preoperative in two groups, and that in observation group was lower than control group, the difference was statistically significant ( P < 0. 05 ). Six months after operation, there were 1 eye with shallow anterior chamber Ⅰ and 2 eyes with non- functional bleb in observation group, and the complication rate was 5. 9%. While there were of 6 eyes with shallow anterior chamber, in which 4 eyes at gradeⅠ, each one at gradeII and Ⅲ. Non-functional blebs in 5 eyes and a scleral flap adhesion complications rate in the control group was 24. 0%, significantly higher than that in the observation group, the difference was statistically significant ( P<0.01).
CONCLUSION: The adjustable sutures combined with trabeculectomy for glaucoma can significantly reduce the postoperative complications. The curative effect is exact and clinically applicable.
2.Analysis of Sponge-associated Culturable and Natural Microbial Community Structure Based on DGGE Fingerprinting
Microbiology 1992;0(03):-
The microbial community structure of 4 kinds of sponges in South China Sea were revealed using culture-independent PCR- DGGE gene fingerprint technique as well as the mixed culturable microorganism. The relationship between the culturable and un-culturable microorganism was studied based on the different fingerprint profile. It was found that there is host specificity for microorganism in different sponges from the same marine area. Culture condition such as medium is an important factor for sponge-associated microbial cultivation and the culturable microorganism amount to only a little part of the total sponge-associated microorganisms.
5.A case of adult Wilms' tumor
Wasilijiangwahafu ; Zhi-Song HE ; Li-Qun ZHOU ;
Journal of Peking University(Health Sciences) 2004;0(03):-
A 35-year-old woman patient,complained of intermittent pain in the left flank for a week.Abdominal ultrasound and computed tomography scan revealed a left renal mass.Nephrectomy was performed,and a final diagnosis of adult Wilms' tumor was made based on histopathology and immunohistology.Chemotherapy was conducted for 4 times with dactinomycin D,vincristine and doxorubicin after surgery.At the time of the last recheck,the patient was alive with no evidence of disease.Adult Wilms' tumor is the exceptional malignant renal tumor.Only 1%-2% of Wilms' tumor is diagnosed in adult patients.Because of unspecific tumor symptoms in adults,the diagnosis is frequently made by histology.The diagnosis of adult Wilms' tumor is difficult to make preoperatively because diagnostic imaging only confirms the presence of a renal mass.Stage and histology are the clinical factors guiding the selection of postsurgical treatment and prognosis.Having retrospected 6 cases of adult Wilms' tumor between 1950 and 2007 and reviewed related reports,we conclude that the proper strategies of adjuvant treatment as applied to childhood Wilms' tumor patients after surgery can conspicuously improve the outcome in adult patients.
6.An investigation of the clinical application of suspended red blood cells
Julin LI ; Zhi LUO ; Weilan HE
Chinese Journal of Blood Transfusion 2001;0(06):-
Objective To investigate the clinical application of suspended red blood cells in Liuzhou,in order to make the transfusion of blood components more reasonable and safer.Methods Retrospective data were collected from 226 patients,who had received the transfusion of 980 units of suspended red blood cells between 2000 and 2006.Results Suspended red blood cells could be used widely to different kinds of patients,and most patients benefit from the treatment.The transfusion of leuko-reduced RBC was even more effective.The age,gender,category of disease,disease severity,hemoglobin level and the amount of transfusion were the key points that affect the therapeutic effect of transfusion.Traumatic hemorrhage was another important factor.Unreasonable clinical transfusion still exists.Conclusion Transfusion of suspended red blood cells is an effective treatment.But when and how to transfuse depend on individual cases.
7.Re-transplantation following adult-to-adult living donor liver transplantation:report of 6 cases
Li-Xin LI ; Qiang HE ; Da-Zhi CHEN ;
Chinese Journal of Organ Transplantation 2005;0(11):-
Objective To summarize the experience and clinical characteristics in liver re- transplantation following adult-to-adult living donor liver transplantation.Methods Due to biliary complication (2 cases),vascular complication (2 cases),chronic rejection (1 case) and hepatitis recur- rence (1 case),liver re-transplantation was performed on 6 patients through modified piggyback liver transplantation.Vascular anastomosis was performed between the hepatic arteries of donor livers and receptor abdominal aorta in 1 case,and the rest were subjected to end-to-end homonymic vascular anastomosis.Results No operative death occurred.Due to primary non-function,1 died after the ope- ration.During the follow-up period,1 had anastomotic stricture of hepatic artery after the operation and was cured by percutaneous venoplasty.The survival of the rest patients was 12,9,6,4 and 3 months respectively.Conclusion Peritoneal adhesion is the operative difficulty for liver re-transplantation following adult-to-adult living donor liver transplantation.
9.Influence of Helicobacter Pylori Infection on Gastric Mucin Expression in Children
zhi-feng, LIU ; li-hua, HAO ; zu-hui, HE
Journal of Applied Clinical Pediatrics 2004;0(07):-
Objective To investigate the influence of Helicobacter pylori(Hp) infection on gastric mucin MUC5AC and MUC6 expression in children.Methods Sixty-six cases with gastric biopsy specimens were obtained from 66 children undergone gastroscopy from Jan.2005 to Jun.2006 for episodic or continuous abdominal pain,nausea,vomiting,abdominal distension,retching and dyspepsia,and so on.Among these children,39 cases were male and 27 cases were female,owning a average age(8.8?3.0)years.These specimens were divided into 2 groups followed by the presence of Hp,which was detected by rapid urease tests and Hp-PCR.Gastric mucin MUC5AC and MUC6 mRNA were also measured by reverse transcription PCR(RT-PCR),and Hematoxylin and Eosin staining were used for pathology observation.Comparisons between every groups were performed using t test and ?2 test,and statistical significance was defined as P
10.In vitro chemosensitivity testing of primary and recurrent breast carcinomas and its clinical significance.
Zhi, LI ; Haiping, SONG ; Wenshan, HE ; Yuan, TIAN ; Tao, HUANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2008;28(6):683-7
In this study, in vitro chemosensitivity testing was conducted on primary cultured breast cancer cells from 96 patients with breast cancer, and the results showed that the cells from a few patients with primary breast cancer developed multidrug resistance (MDR) prior to the first chemotherapy exposure. All the cells from the recurrent cancer patients had MDR. The findings suggested that patients having MDR would benefit from high-dose chemotherapy (HDC) regimens. In vitro chemosensitivity screening, which was aimed at improving the therapeutic efficacy and minimizing side effects, helps in choosing individualized treatment for breast cancer.
Antineoplastic Agents/*pharmacology
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Breast Neoplasms/*drug therapy
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Breast Neoplasms/pathology
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Drug Resistance, Multiple
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Drug Resistance, Neoplasm
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Drug Screening Assays, Antitumor/*methods
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Neoplasm Recurrence, Local/*drug therapy
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Tumor Cells, Cultured