1.A clinical efficacy and safety study on coronary heart disease and angina treatment with Puerarin Injection
Zhi-Kuan LUO ; Yong LIU ; Huan-Ming LI
Chinese Journal of Epidemiology 2012;33(6):614-616
Objective To observe the clinical efficacy and safety of Puerarin Injection treatment on angina pectoris.Methods 388 patients with angina pectoris,enrolled to Tianjin Fourth Central Hospital during January 2009 and February 2011 were selected and randomly divided into treatment or control groups with 194 patients of each.Based on the conventional therapy program,one group was given Puerarin Injection as treatment group while,the other was given with Danshen Injection as control group.Clinical efficacy,the attack rate of angina pectoris,oxygen consumption,iadices on electrocardiogram,haemorheology and other adverse reactions among the two groups were compared.Results The total efficacy of the treatment group (88.14%,171/194)was significantly higher than the control group (61.86%,120/194) and the difference was statistically significant (P<0.05).During the treatment,no significant adverse events were noticed in both of the two groups of patients.Conclusion The Puerarin Injection treatment program on angina pectoris seemed effective and safe.
2.A case-control study on genetic and environmental factors regarding polydactyly and syndactyly
Jia-You LUO ; Chu-Hui FU ; Kuan-Bao YAO ; Ru-Shan HU ; Qi-Yun DU ; Zhi-Yu LIU
Chinese Journal of Epidemiology 2009;30(9):903-906
king condition before pregnancy were associated with the development of polydactyly and syndactyly.
3.Clinical studies on different coronary artery interventional therapies through femoral artery or radial artery approaches
Feng HE ; Huan ZHANG ; Huan-Ming LI ; Yong LIU ; Xiao-Chun XING ; Xiu-Feng GU ; Zhi-Kuan LUO
Chinese Journal of Epidemiology 2012;33(5):534-535
Objective To compare the clinical efficacies regarding femoral artery or radial artery approaches on coronary artery interventional therapies.Methods 360 patients were randomly divided into intervention group via femoral artery (TFI) or transradial coronary intervention (TRI) group.Postoperative observation on the two said groups of patients with vascular lesion characteristics,feasibility factors ( success rate of interventional therapy puncture,time of operation and hospitalization)and complications,were made.Results There were no significant differences between the two groups on the characteristics of vascular lesion (P>0.05).Success rates of the two groups were 97.78% and 96.67% respectively.The differences on success rate,time of operation were not statistically significant (P>0.05) while the average time of puncture,the mean duration of hospitalization and the rates of complications were significantly different ( P< 0.05 ).Conclusion The two methods under comparison had similar success rate and feasibility.However,the complications related to radial artery interventional therapy were much less than the femoral artery interventional therapy.As having better safety,radial artery interventional therapv seemed to have applicable value on clinical oractice.