Objective To explore the effects of nursing intervention on the anxiety of nasopharyngeal carcinoma (NPC) patients in their first chemotherapy.Methods Totals of 80 NPC patients were randomly divided into control group and intervention group,with 40cases each group.Control group received conventional care,while intervention group received the comprehensive nursing intervention such as relaxation training,cognitive intervention,family supporting and sleep care and so on.Self-rating anxiety scale (SAS) and St.Mary' s hospital sleep questionnaire (SMH) were used to investigated patients at the first hospital day,the day before chemotherapy and the last day of chemotherapy.Results There was no difference of the SAS and SMH score of patients in the first hospital day between two groups ( P ＞ 0.05 ),and the average score of SAS of two groups was more than 50.In the control group,the average score of SAS in the day before chemotherapy and the last day of chemotherapy was (59.42 ± 6.98) and ( 56.98 ± 5.69 ),respectively,higher than ( 48.67 ± 7.05 ) and (45.35 ± 5.93 ) of the intervention group,and the difference was statistically significant ( t =6.853,- 6.538,respectively;P ＜0.01 ).The average score of SMH of control group in the day before chemotherapy and the last day of chemotherapy was ( 13.55 ± 2.17 ) and ( 14.92 ± 2.40),and that of intervention group was ( 17.23 ± 2.82 ) and ( 18.03 ± 2.35 ),and the difference was statistically significant ( t =- 5.839,P ＜ 0.01 ).After intervention,in the intervention group,the scores of SAS was decreased and the score of SMH was increased(F =36.45,20.27,respectively;P ＜ 0.01 ).Conclusions The comprehensive care can effectively relieve patients' anxiety,improve their sleep,and encourage them to actively cooperate with chemotherapy,so it is worth to be widely applied.

Adolescent ; Adult ; Aged ; Cardiomyopathy, Hypertrophic ; genetics ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged ; Mutation ; Troponin T ; genetics