3.Analysis of paraplegia during transarterial chemoembolization in liver cancer
Bo ZHOU ; Zhi-Ping YAN ; An-Le WU ;
Journal of Interventional Radiology 2006;0(12):-
Objective To evaluate the pathophysiology of paraplegia during transarterial chemoembolization in liver cancer and investigate effective management and prevention for improving clinical situation and relieve major symptoms.Method 2758 patients accepted TACE procedure because of liver cancer(and/or combined with remote metastasis),demonstrated 4 cases suffering from paraplegia(3 males,1 female)since Mar.2003 to Feb.2005,with mean age of(51?14)years old,The operative records and the clinical features after chemoembolization were summarized in detail.Results The incidence of paraplegia was 0.145%,with major symptoms of dysesthesia and hypokinesise emerging within 4 hours after TACE,and most symptoms aggravating gradually within 24-48 hours untill paraplegia appeared,and then turned to stabilization about 5-7 days,with their body functions partial recovery in 2 months.Conclusion More attention should be paied to prevent ectopic embolization of spinal cord vessels originating from extrahepatic collateral arteries during TACE or TAE.
4.Pituitary carcinoma: report of a case.
Jing ZHOU ; Nan-yun LI ; Zhi-qiang ZHANG ; Chi-yuan MA ; Bo YU ; Hang-bo ZHOU
Chinese Journal of Pathology 2013;42(2):123-125
Adenoma
;
pathology
;
Brain Neoplasms
;
secondary
;
Chromogranin A
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metabolism
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Neoplasm Recurrence, Local
;
Pituitary Neoplasms
;
diagnosis
;
metabolism
;
pathology
;
surgery
;
Reoperation
;
Synaptophysin
;
metabolism
;
Temporal Lobe
;
pathology
7.Space-occupying lesion in left upper lobe of lung.
Xin-hua ZHANG ; Qun-li SHI ; Zhi-yi ZHOU ; Wen-bin HUANG ; Hang-bo ZHOU ; Xiao-jun ZHOU
Chinese Journal of Pathology 2006;35(7):432-433
Adult
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Antibodies, Monoclonal
;
metabolism
;
Diagnosis, Differential
;
Follow-Up Studies
;
Humans
;
Immunohistochemistry
;
Lung Neoplasms
;
metabolism
;
pathology
;
surgery
;
Male
;
MyoD Protein
;
metabolism
;
Pneumonectomy
;
Pulmonary Veins
;
metabolism
;
pathology
;
surgery
;
S100 Proteins
;
metabolism
;
Sarcoma, Alveolar Soft Part
;
metabolism
;
pathology
;
surgery
;
Vascular Neoplasms
;
metabolism
;
pathology
;
surgery
8.Chicory extract's influence on gut bacteria of abdominal obesity rat.
Bo-Yu SUN ; Bing ZHANG ; Zhi-Jian LIN ; Li-Yu LI ; Hong-Po WANG ; Jun ZHOU
China Journal of Chinese Materia Medica 2014;39(11):2081-2085
OBJECTIVETo investigate the efficacy mechanisme of chicory extract interventing abdominal obesity rat from the aspect of gut bacteria.
METHODMale SD rats were randomly divided into five groups, namely the normal group, model group, large and small dose group of chicory and the fenofibrate group. Normal group was given deionized water, the other group was given fructose water and give the medical treatment of chicory and fenofibrate. Assay triglycerides, total cholesterol, LDL and HDL by biochemical methods and measure body weight and abdominal circumference and microscopicly observe the count changes of gut bacteria through real-time PCR method.
RESULTCompared with normal group, the triglyceride level and abdominal circumference were significantly higher (P < 0.05), weight and high-density lipoprotein increased but no significant changes and E. coli, lactobacillus increased significantly. Compared with model group, chicory extract large and small dose group and the fenofibrate group can significantly reduce triglyceride levels (P < 0.05), reduce the number of E. coli and Lactobacillus and increase the number of bifidobacteria. The fenofibrate group can significantly reduce total cholesterol and high-density lipoprotein levels.
CONCLUSIONThe chicory's treatment effect on abdominal obesity is significant. The efficacy mechanisme intervention abdominal obesity may be related to the reduction of the number of lactic acid bacteria and E. coli and the increase of bifidobacteria.
Animals ; Bacteria ; classification ; genetics ; isolation & purification ; Biodiversity ; Chicory ; chemistry ; metabolism ; Cholesterol ; metabolism ; Gastrointestinal Tract ; microbiology ; Humans ; Male ; Microbiota ; Obesity, Abdominal ; metabolism ; microbiology ; Plant Extracts ; metabolism ; Rats ; Rats, Sprague-Dawley ; Triglycerides ; metabolism
9.Application of acupuncture in imaging of changing pyloric antrum and duodenal bulb metamorphosis.
Chinese Acupuncture & Moxibustion 2006;26(9):633-634
OBJECTIVETo probe into the effect of acupuncture in imaging diagnosis on changing pyloric antrum and duodenal bulb metamorphosis, and provide reliable evidence for confirming pathological characters.
METHODSAmong 30 cases needing image examination, 18 cases had metamorphosis of duodenal bulb and 12 cases had metamorphosis of pyloric antrum. Acupuncture was given at Zusanli (ST 36) with uniform reinforcing-reducing method, and with moderate-strong stimulation. The needle was retained for 2 min. After pressing point Zhongwan (CV 12), changes of image were investigated.
RESULTSAfter acupuncture, the metamorphosis alleviated in 26 cases, with an effective rate of 86.7%.
CONCLUSIONThis method is simple, convenient and objective with no adverse effects.
Acupuncture Points ; Acupuncture Therapy ; Adolescent ; Adult ; Duodenum ; pathology ; Female ; Humans ; Male ; Middle Aged ; Pyloric Antrum ; pathology
10.Effects of tetrandrine on neuronal apoptosis,bcl-2 and bax expressions following acute spinal cord injury In comparison with methylprednisolone
Chunshan LUO ; Xiaobin TIAN ; Lei WANG ; Bo LI ; Zhi PENG ; Zhuojia ZHOU ; Yuekui JIAN ; Weifeng ZHAO
Chinese Journal of Tissue Engineering Research 2010;14(41):7770-7774
BACKGROUND:Studies have demonstrated that tetrandrine has protection on acute spinal cord injury,but the specific mechanism remains poorly understood.OBJECTIVE:To study the protection of tetrandrine on rat acute spinal cord injury and to study its mechanism from apoptosis pathway.METHODS:A total of 100 rats were randomly divided into 4 groups.All rats were prepared for spinal cord injury models using modified Allen method except that in the sham-surgery group.Methylprednisolone and tetrandrine was injected into rats in the methylprednisolone and tetrandrine groups by tail intravenous injection prior to and at 24,48 hours after model preparation.The same volume of physiological saline was injected in the sham-surgery and model groups.Basso-BeatUe-Bresnahan(BBB score)was recorded at 8 hours,1,3,7 and 14 days after model preparation.The morphological changes of spinal cord injury sites were observed by hematoxylin-eosin staining and the expressions of bcl-2 and bax were determined by immunohistochemistry.RESULTS AND CONCLUSION:The BBB score of methylpradnisolone and tetrandrine groups were significantly higher than that model group at 7 and 14 days(P<0.05),but there were no significant difference between the methylprednisolone group and tetrandrine group(P>0.05).Hematoxylin-eosin staining showed that the spinal cord injured severely at 3-7 days,the injury degree in the methylpradnisolone group and tetrandrine group was slighter than that of the model group,with smaller bax expression and greater bcl-2 expression(P<0.01).The findings demonstrated that,tetrandrine is able to protect neurons from apoptosis and promote the nerve function recovery by inhibiting the expression of Bax and promoting the expression of Bcl-2.Its effect is not inferior to methylprednisolone.