2.Research progress on mitochondrial oxidative stress and corresponding targeted delivery systems in Alzheimer's disease
Ling-ling ZHOU ; Kang QIAN ; Peng YANG ; Qi-zhi ZHANG
Acta Pharmaceutica Sinica 2022;57(6):1630-1640
Mitochondrial oxidative stress has been recognized as a preliminary and critical factor that aggravates the pathological cascade of Alzheimer's disease, which induces the production of
4.The effect of intermittent moderate hypoxia on mouse nutritive metabolism.
Ling QIN ; Sai-lan WEN ; Zhi SONG
Chinese Journal of Applied Physiology 2007;23(2):177-179
Altitude
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Animals
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Blood Glucose
;
metabolism
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Cholesterol
;
blood
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Hypoxia
;
metabolism
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Mice
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Weight Loss
5.Early exposure to food antigens and food allergies of children.
Chinese Journal of Pediatrics 2010;48(8):588-591
Antigens
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immunology
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Child
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Female
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Food Hypersensitivity
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etiology
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Humans
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Infant, Newborn
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Maternal Exposure
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Milk Hypersensitivity
;
etiology
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Milk, Human
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immunology
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Pregnancy
8.Effect of Tripterygium glycosides on thyroid function and auto-antibody in patients with Graves disease.
Ling TANG ; Zhi-qing LIANG ; Ke SU
Chinese Journal of Integrated Traditional and Western Medicine 2003;23(4):294-295
Adult
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Antithyroid Agents
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therapeutic use
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Autoantibodies
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blood
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Drugs, Chinese Herbal
;
therapeutic use
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Female
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Glycosides
;
therapeutic use
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Graves Disease
;
drug therapy
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immunology
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Humans
;
Immunosuppressive Agents
;
therapeutic use
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Male
;
Methimazole
;
therapeutic use
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Middle Aged
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Phytotherapy
;
Tripterygium
;
chemistry
9.A long-term follow-up report of 15 cases of hepatolithiasis after Oddi sphincteroplasty
Xiaofeng LING ; Zhi XU ; Nengwei ZHANG
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
0.05). Conclusions The upstream lesions of biliary tract must be dealt with thoroughly in the treatment of hepatolithiasis. EST should not be the first choice for hepatolithiasis preparatory to determining whether or not lesions like stricture are present in intrahepatic ducts.
10.Comparison of long-term outcomes of different treatment for hepatolithiasis
Lixin WANG ; Zhi XU ; Xiaofeng LING
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To explore rational and effective treatment strategies by comparing long-term effects of different treatment methods for hepatolithiasis. Methods One hundred and fifty-nine cases of hepatolithiasis treated in this hospital from January 1993 to December 2002 were analyzed retrospectively.Five treatment methods: conservative treatment,choledocholithotomy followed by choledochostomy,hepatolobectomy,hepaticojejunostomy,and hepaticoplasty with the conservation of the Oddi's sphincter,were compared in respect of postoperative complications and long-term outcomes.Results Out of the 159 cases,follow-up was completed in 146 cases(91.8%,146/159) for 2~12 years(median,7 years).Of 16 cases of conservative treatment,15 were followed.Cholangitis occurred in all the 15 cases,with 1 fatal case.Of 47 cases of extrahepatic surgical exploration,the incidence of residual stones was 100%.Follow-up in 43 cases found 32 cases of cholangitis(74.4%) with 7 fatal cases.Of 16 cases of hepatolobectomy,residual stones were noted in 3 cases(12.5%).Follow-up in 15 cases found 4 cases of cholangitis(26.7%) with 1 fatal case.Of 32 cases of hepaticojejunostomy,residual stones were found in 11 cases(34.4%).Follow-up in 29 cases found 14 cases of cholangitis(48.3%) with 3 fatal cases.Of 48 cases of sphincter-sparing operation,residual stones were found in 8 cases(16.7%).Follow-up in 44 cases found 7 cases of cholangitis(15.9%).The incidence of residual stones was significantly higher in cases of extrahepatic surgical exploration than in cases of other treatment(P=0.000).The recurrence rate of cholangitis was significantly higher in cases of conservative treatment and extrahepatic surgical exploration than in cases of other treatment(P