1.Treatment method and timing for dacryocystitis in different months -old children
International Eye Science 2016;16(10):1905-1907
AIM: To explore the treatment method and timing for neonatal dacryocystitis in different month-old children.
●METHODS: A total of 180 children ( 207 eyes ) with dacryocystitis who were admitted to our hospital between Jan. 2010 and Dec. 2014 were selected as the study subjects. According to months of age, they were divided into <3 months old group (n=41, 45 eyes), 3-6 months old group (n=75, 91 eyes) and 6-12 months old group (n=64, 71 eyes). Three groups were respectively treated with lacrimal massage combined with antibiotics, lacrimal duct washing with pressure and lacrimal duct probing, etc. The curative effect was compared between different months old children with dacryocystitis. The cure rate was statistically analyzed. The mean times of treatment was recorded and the best time for treatment was summarized.
●RESULTS:1) Hasner valvular obstruction was common in different months old children, and the proportion was higher than that of children with nasolacrimal duct bony part obstruction (P<0. 05). The proportion of children with nasolacrimal duct bony part obstruction in 6 - 12 months old group was higher than that in <3 months old group and that in 3-6 months old group (P < 0. 05). The proportion of children with Hasner valvular obstruction was lower than that in<3 months old group and that in 3-6 months old group (P<0. 05); 2) the number of cured eyes in < 3 months old group was higher than that in 3-6 months old group and that in 6-12 months old group ( P<0. 05), and the number of cures eyes in 3-6 months old group was higher than that in 6-12 months old group ( P<0. 05);3) the effective rates of lacrimal duct washing with pressure in <3 months old group and 6-12 months old group were similar, lower than that in 3-6 months old group (P<0. 05); 4) the effective rates of lacrimal duct probing in the three group were higher than 90% ( P>0. 05);5) the times of treatment in 3-6 months old group and 6-12 months old group was more than that in <3 months old group (P<0. 05), and that in 6-12 months old group was more than that in 3-6 months old group ( P <0. 05).
● CONCLUSION: For < 3 months old children with dacryocystitis, conservative treatment like lacrimal massage should be preferred. For children without effect, lacrimal duct washing with pressure and lacrimal duct probing should be given; For 3-6 months old children, lacrimal duct washing with pressure is preferred, and for 6 - 12 months old children, lacrimal duct probing is recommended.
2.Acquired toxoplasmosis of infant: report of a case.
Chinese Journal of Pediatrics 2009;47(5):337-337
Humans
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Infant
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Male
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Toxoplasmosis
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etiology
3.Comparison of cyclopentolate and atropine on cycloplegia in children
Zhi, WANG ; Qi-Guo, XIAO ; Zhi-Gang, FEI
International Eye Science 2014;(8):1545-1547
AIM: To compare the effectiveness on 10g/L cyclopentolate and 10g/L atropine on cycloplegia in children before optometry.
METHODS:Eighty eyes of 40 children among 4-12 years old with refractive error were recruited in this study. 10g/L cyclopentolate eye drops were topically administered once per 5min for 3 times and optometry was performed after 45min. Three days after that, 10g/L atropine sulfate eye gel then was used 3 times per day for consecutive 3d and again the refractive diopter was obtained at the 4th d. The differences of the results in retinoscopy refraction were compared between 10g/L cyclopentolate eye drops and 10g/L atropine sulfate eye gel.
RESULTS: Therefraction results of those given 10g/L cyclopentolate eye drops and 10g/L atropine sulfate eye gel were no statistical different in both 4-8 years group and 9-12 years group with myopia (≤-3. 00D) (P=0. 411, 0. 924). The differences of refraction results of both the drugs were significant in 4 - 8 years group with low hypermetropia, medium hypermetropia and high hypermetropia (P=0. 007, 0. 007, 0. 009). No significant difference was found in 9 - 12 years group with low hypermetropia (P= 0. 592), given 10g/L cyclopentolate eye drops and 10g/L atropine sulfate eye gel, but the differences of refraction results of both the ophthalmic preparations above were significant in 9-12 years group with medium and high hypermetropia (P=0. 039, 0. 012).
CONCLUSION:Both 10g/L cyclopentolate eye drops and 10g/L atropine sulfate eye gel have the cycloplegic effects, but their cycloplegic effects are significant different among hypermetropia children. Thus, the reasonable cycloplegic should be chosen according to the specific situation.
4.Infantile kala-azar: report of a case.
Zhi-gang LIU ; Xiao-jie LIN ; Xiao-hong LIU
Chinese Journal of Pediatrics 2008;46(3):238-238
5.Multiple tartaric of hand and foot: a case report.
Xiao-gang LIU ; Yi-lin LIU ; Zhi-jie XIE
China Journal of Orthopaedics and Traumatology 2013;26(12):1031-1032
Gout
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diagnostic imaging
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surgery
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Humans
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Radiography
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Tartrates
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analysis
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Young Adult
6.The regular distribution of Ca2+ in hypothalamus of the rats exposed to the infrasound of 90 dB.
Zhi-gang ZHAO ; Xiao-xian TANG ; Shuang WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(8):492-493
Acoustic Stimulation
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adverse effects
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Animals
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Calcium
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metabolism
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Female
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Hypothalamus
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metabolism
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Neurons
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metabolism
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Rats
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Rats, Sprague-Dawley
7.Isolation and characterization of chronic myelogenous leukemia bone marrow mesenchymal stem cells and their hematopoiesis support ability
Zhi-Gang ZHAO ; Xiao TANG ; Wang QIONG ; HONG-XIANG
Chinese Journal of Organ Transplantation 2005;0(10):-
Objective To study the characteristics of mesenchymal stem cells(MSCs)derived from chronic myelogenous leukemia(CML)patients' bone marrow and examine their hematopoiesis support in vitro.Methods MSCs from CML were obtained and cultured.Immunophenotype and in vitro differentiation capacities were investigated.Moreover,the Ph chromosome and bcr/abl gene of CML derived MSCs were detected.The expression of cytokines was detected by RT-PCR,and hema- topoiesis support of MSCs in vitro was detected by long-term bone marrow culture and the methylcel- lulose progenitor assay.Results CML derived MSCs showed a typical fibroblast like morphology. They were positive for CD29,CD44 and CD105,while negative for CD14,CD31,CD45,CD34 and HLA-DR.Under suitable conditions,CML derived MSCs could differentiate into osteoblasts and adi- pocytes.Further,CML derived MSCs showed a normal choromosome,and did not express bcr/abl gene.At last,they expressed hematopoiesis cytokines and possessed ability of hematopoiesis support in vitro.Conclusion There are MSCs with multidirectional differentiation potential in CML bone mar- row and they possess the ability of hematopoiesis support.
9.Expression of ciliary neurotrophic factor in visual cortex of form deprivation amblyopia cat and its effect
Zhi, WANG ; Xiang-zhen, HE ; Qi-guo, XIAO ; Zhi-gang, FEI ; Xi, LI
Chinese Journal of Experimental Ophthalmology 2012;30(9):800-804
Background Researches demonstrated that ciliary neurotrophic factor (CNTF) can enhance survival and promote differentiation of neutron.Meanwhile,CNTF also is thought to play an important role in the development of visual pathway.But,less studies are reported in the relationship of CNTF and form deprivation amblyopia.Objective This study was to investigate the expressions of CNTF in visual cortex area 17 in form deprivation amblyopia model.Methods Twelve 4-week-old cats were randomized into normal group and form deprivation amblyopia group.Monocular form deprivation amblyopic models were established in 6 cats by eyelids suture method.Pattern visual evoked potential(P-VEP) was recorded to evaluate the amblyopic models 16 weeks later following the eyelids suturing.Then,bilateral visual cortex tissue was incised at a vertical in sagittal axis fashion to prepare the section.Nissl staining was used to detect the morphologies of neurons.Expression of CNTF in Ⅰ-Ⅵ layers of visual cortex area 17 was located and quantified by immunochemistry.The positive cell number and gray scale for CNTF were calculated and compared between two groups.The use of the animals complied with Regulations for the Administration of Affairs Coucerning Experimental Animals by State Science and Technology Commission.Results Compared with the normal group,P-VEP amplitude was significantly reduced (6.11 ±1.56 μV vs.11.42±t.92 μV) and latency was significantly prolonged(75.77±9.83 ms vs.58.56±7.17 ms) in the form deprivation amblyopia group (t=5.272,3.464,P<0.05).Nissl staining showed that the number of neurons in the form deprivation amblyopia group was less than that in the normal group.In the form deprivation amblyopia group,neurons became shrinkage and turned round,cytoplasmic processes get shortened,and the nucleus became small.The number of Nissl bodies was decreased.lmmunochemistry showed the positive neutrons for CNTF in Ⅰ-Ⅵ layers of visual cortex area 17 in hoth normal cats and model cats with the more positive cells in Ⅱ-Ⅳ layers.Compared with the normal group,the positive cell number for CNTF was significantly reduced in Ⅱ-Ⅳ layers of visual cortex area 17 in the form deprivation amblyopia group (Ⅱ layer:95.93±8.24 vs.116.25±6.52;I layer:102.65±7.45 vs.125.23±8.21;Ⅳ layer:l10.65±6.85 vs.139.54±4.26) (t=4.737,4.989,8.773,P<0.05).In addition,the gray scale of CNTF positive cells was significantly lower in Ⅱ-Ⅳ layers of visual cortex area 17 in the form deprivation amblyopia group than that the normal group (Ⅱ layer:106.98 ± 8.86 vs.138.65 ± 6.38 ; Ⅲ layer:109.56 ± 8.69 vs.149.59 ±8.55;Ⅳ layer:l16.65 ±9.52 vs.155.76±9.87) (t=7.105,8.043,6.986,P<0.05).Both CNTF positive cell number and gray scale in Ⅰ,Ⅴ,Ⅵ layers of visual cortex area 17 had no significant differences between two groups (P>0.05).Conclusions Form deprivation in critical period of a new born animal may lead to distributing abnormality of CNTF in visual cortex,which maybe play a role in the development of form deprived amblyopia.
10.Effects of fluid resuscitation on thoracoabdominal injury combined with hemorrhagic traumatic shock
Zhi-Wei FAN ; Xiao-Guang LU ; Xin KANG ; Wei-Guang LIU ; Yi-Gang WANG ; Dan WANG ; Hong-Gang PANG ;
Chinese Journal of Emergency Medicine 2006;0(11):-
Objective To study effects of fluid resuscitation on thoracoabdominal injury combined with hemorrhagic traumatic shock.Method A total of 98 patients,who were treated in Affiliated Zhongshan Hospital of Dalian University from November 2004 to December 2006,were retrospectively analyzed.The patients were diagnozed according to Surgery(fifth edition).Patients were divided into delayed fluid resuscitation group(n= 51)and immediate fluid resuscitation group(n=47).Patients in delayed fluid resuscitation group were given with balanced salt solution for the body to maintain basic requirements.Patients in immediate fluid resuscitation group were rapidly administered with a lot of isotonic crystaUoid and(or)colloid solution after admission. Hemoglobin,platelet count,hematocrit,blood lactic acid,basedeficit,preoperative resuscitation time and mortality were compared between the two groups.Paired t test and variance analysis or x~2 test were used.Results The transfusion fluid volume of delayed group and immediate group was(1586?346)ml,(3520?575)ml, respectively,with P value