1.A Preliminary Analysis of Expertise-Novice Effect on Representational Momentum between College Athletes and Students
Chinese Journal of Sports Medicine 2017;36(4):320-327
Objective To explore whether expertise-novice effect on representational momentum exist among athletes in the university football and volleyball team and common college students.Methods We used implied motion paradigm in experiment 1 and smooth motion paradigm in experiment 2.Results There were no significant differences on representation momentum among football players,volleyball players and college students in the implied motion paradigm.When moving to the right at a high speed,college students' displacement was larger than athletes in smooth motion paradigm,but no significant differences were found between football and volleyball players in the displacement.Conclusion The expertise-novice effect on representational momentum has been found under the condition of high speed and moving right using smooth paradigm.There is no difference between football and volleyball on representational momentum.
2.Mesenchymal stem cells as salvage therapy for steroid resistant acute graft-versus-host disease following haploidentical hematopoietic stem cell transplantation.
Mei XUE ; Zhi-dong WANG ; Lei DONG
Chinese Journal of Hematology 2011;32(12):878-880
Adolescent
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Adult
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Child
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Child, Preschool
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Female
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Graft vs Host Disease
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therapy
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Hematopoietic Stem Cell Transplantation
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Humans
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Immunosuppressive Agents
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therapeutic use
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Male
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Mesenchymal Stem Cell Transplantation
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methods
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Salvage Therapy
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methods
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Treatment Outcome
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Young Adult
3.Application of apparent diffusion coefficient value and its coefficient variance in differentiating the cerebellopontine angle tumors
Zhi TAN ; Dong WANG ; Wubiao CHEN
Journal of Practical Radiology 2015;(4):529-532
Objective To investigate the usefulness of apparent diffusion coefficient (ADC)value and its coefficient variance (CV) in differentiating the cerebellopontine angle tumors.Methods 5 1 cases of cerebellopontine angle tumors comfirmed by surgery were enrolled ,in which cerebral enhanced MRI were obtained MRI data of different type of tumors were analyzed.ADC value and its CV of tumors were calculated.Results There were 24 cases of schwannoma,14 cases meningioma,7 cases metastases,4 cases epider-moid cyst and 2 cases dermoid cyst.There were obvious differences on ADC value’s CV among the schwannoma,meningioma and metastases (t=-1.31,P =0.03;t=-0.56,P =0.04;t =0.07,P =0.04).ADC value of schwannoma was only significant higher than that of meningioma (t=-2.5,P =0.04).Conclusion In combination with MRI,ADC value and its CV have a higher value in differential diagnosis of cerebellopontine angle tumors.
4.Effects of azithromycin on the formation of nontypeable haemophilus influenzae biofilm on endotracheal tubes
Ying WANG ; Dong WANG ; Zhi GUO ; Shumei SHI
Chongqing Medicine 2016;(1):40-41,46
Objective To observe the formation of biofilms on endotracheal tubes ,and to determine the effect of azithromycin on Haemophilus influenzae in biofilms .Methods One hundred and twenty Wistar rats were intubated with a silicone tube ,80 of them(40 rats were model group and 40 were medicine group) were infected by bacteria to establish the animal models of endotra-cheal tube infections the others were ues as control gruop .Formation of biofilms was detected by scanning electron microscope .Via-ble cells counting was carried out to evaluate the effect of azithromycin orally on biofilms on endotracheal tubes .Results Uneven biofilms were formed on the surface of endotracheal tubes ,and slim bodied of bacteria enclosed by a lot of extracellular matrix .Via-ble cells counting was reduced in medicine group compared with model group .Conclusion Haemophilus influenzae can form bio-films on endotracheal tubes .Azithromycin can exert inhibitory effect on haemophilus influenzae biofilms formed on endotracheal tubes .
5.Meta-analysis of internal fixation versus hip replacement in the treatment of trochanteric fractures.
Jian-Bin DONG ; Zhi-Yong WANG ; Hao LU ; Yuan TIAN ; Xin-Rui WANG ; Zhi-Qiang ZHANG
China Journal of Orthopaedics and Traumatology 2015;28(3):245-251
OBJECTIVETo compare the efficacy of internal fixation (including PFNA and PFN) versus hip replacement (including FHR or THA) in the treatment of trochanteric fractures in adults.
METHODSReports of studies using randomized controlled trials (RCT) to compare internal fixationg with hip replacement in the management of intertrochanteric fractures were retrieved (up to January 1, 2013) from the Cochrane Library, PUBMED Data, CNKI (China National Knowledge infrastructure), Elsevier, the Chinese Biomedical Database, Wanfang Data, and manually. Methodological quality of the trials was critically assessed, and relevant data were extracted. Statistical software RevMan 5.0 was used for data-analysis.
RESULTSSeven articles were included in the meta-analysis. The results showed that,compared internal fixation with hip replacement,there were statistical significance in the duration of surgery time [WMD = -2.66, 95% CI (-5.25,-0.06), P = 0.05], intra-operative blood loss [WMD = -24.20, 95% CI (-30.38, -18.02), P < 0.000 01], hospital stays time [WMD = -4.72, 95% CI (-5.18, -4.25), P < 0.000 01], bearing load time [WMD = -29.54, 95% CI (-30.77, -28.31), P < 0.000 01], total complications rate [WMD = 0.15, 95% CI (0.11, 0.22), P < 0.000 01], the good rate of Harris scores [WMD = 1.09, 95% CI (0.54,1.32), P < 0.05]. However, there were no statistical significance in the rate of deep venous thrombosis [WMD = 1.09, 95% CI (0.47, 2.55), P > 0.05]. CON- CLUSION: Hip replacement (containing FHR or THA) for the treatment of intertrochanteric fractures is superior to internal fixa- tion in regards to the duration of surgery time, the mean duration of hosipital stays, mean post-operative down time, intra-opera- tive blood loss, the rate of post-operative good Harris scores. But there is not enough evidence to show any difference between hip replacement (containing THA or FHR) and internal fixation in regards to the rate of deep venous thrombosis. However, internal fixation for the treatment of intertrochanteric fractures is superior to hip replacement (containing FHR or THA) in regards to total complications rate.
Arthroplasty, Replacement, Hip ; methods ; Fracture Fixation, Internal ; methods ; Hip Fractures ; surgery ; Humans
6.Killing effect of IL-12-activated A-NK cells on human hepatocellular carcinoma HepG-2 cells in vitro.
Zhi-Hua WANG ; Dong-Lu ZHAO ; Chun-Yan ZHANG
Chinese Journal of Oncology 2007;29(6):423-424
Animals
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Carcinoma, Hepatocellular
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blood supply
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pathology
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therapy
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Cell Line, Tumor
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Cells, Cultured
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Cytotoxicity, Immunologic
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immunology
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Female
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Humans
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Interleukin-12
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pharmacology
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Interleukin-2
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pharmacology
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Killer Cells, Natural
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cytology
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drug effects
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immunology
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Liver Neoplasms, Experimental
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blood supply
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pathology
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therapy
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Lymphocyte Activation
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drug effects
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immunology
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Male
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Mice
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Mice, Inbred BALB C
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Mice, Inbred C57BL
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Microcirculation
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drug effects
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Random Allocation
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Xenograft Model Antitumor Assays
7.Six Cases of Pulmonary Cavity in Children
zhi-liang, YANG ; gui-lian, SUN ; dong-ying, WANG
Journal of Applied Clinical Pediatrics 2006;0(16):-
Objective To investigate the clinical feature,image of CT scan pulmonary,diagnosis and treatment response in children with pulmonary cavity,and discuss the method of diagnosis and the tactics of treatment for pulmonary cavity in children.Methods A retrospective study of 6 patients with pulmonary cavity,who were diagnosed and treated from Jul. 2003 to Oct. 2009 in Department of Pediatrics of the First Hospital Affiliated to China Medical University.The clinical manifestations,laboratory tests,image of CT scan pulmonary,microbiological evidence,diagnostic procedure and treatment response were collected and evaluated.Results Six patients all didn′t have history of lung di-sease,there were 4 boys and 2 girls,8-15 years old,average age was 10.5 years old.Two cases of them had unrelated pulmonary underlying diseases,1 case had hyperthyroidism,and the other had juvenile idiopathic arthritis and had complication of macrophage activation syndrome,the other 4 cases had no obvious history.All cases had fever (38-40 ℃),3 cases had cough and 1 case had chest pain.Staphylococcus aureus were cultured in 2 cases,no bacteria was cultured in other 4 cases;the count of white blood cell decreased in 2 cases and increased in 4 cases;C-reactive protein increased in 5 cases and was normal in 1 case;plasma IgE level increased in 2 cases and was normal in other 4 cases;plasma 1,3-beta-D-glucan of all 6 cases were negative.Pulmonary cavities were found in the first CT scan of the lungs in 5 cases and only 1 case of patient′s pulmonary cavities was found in the second CT scan of the lung.Five cases were diagnosed infective causes,1 case was diagnosed noninfectious cause,5 cases of infective causes had been treated with anti-microbial drugs for at least 1 week,1 case of noninfectious cause were treated with methylprednisolone cobined cyclosporin A for 2 weeks.Pulmonary CT scan was rechecked in all cases,and the state of the cases were improved before discharged from hospital.Conclusions The causes of pulmonary cavity in children are not only infective factors,but also some non-infective disease,especially some changes of image of pulmonary CT scan has diagnostic value,detailed past medical history and appropriate rechecking of chest radiographic check are very necessary for diagnosis,according to the result of microbial inspection and evaluation of treatment effect in time and then adjust the treatment protocols.
8.Dominant factors impacting on non-motor symptoms in Parkinson's disease
qing, DONG ; zhi-ying, WANG ; yan-sheng, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(08):-
Objective To evaluate the distribution of non-motor symptoms(NMS) and dominant factors impacting on the prevalence of NMS in Parkinson's disease(PD). Methods The NMS questionnaire(NMSQuest) was administered to 128 patients(PD group) and 128 healthy adults(control group).The distribution of items of NMS was analyzed between the two groups,and clinical characteristics were also collected to assess the dominant factors impacting on the prevalence of NMS. Results There were significant differences in the prevalence of NMS between the two groups(P
10.Regulation of estrogen, interleukin-6 and interleukin-8 in ovarian cancer cells
Yue WANG ; Jie YANG ; Yan GAO ; Lijie DONG ; Zhi YAO
Chinese Journal of Microbiology and Immunology 2008;28(9):799-804
Objective To discover the reciprocal regulation and its molecular mechanism of estro-gen, IL-6 and IL-8 in ovarian cancer cells. Methods Based on our previous studies, the effect of 17β-estradiol (E2) on the expression levels of IL-6, IL-8 and their respective receptors was investigated. Mean-while, the effect of IL-6/IL-8 on estrogen receptor (ER) expression and estrogen-dependent transcriptional activation was analyzed. Gene expression profile analysis revealed that CAOV-3 and OVCAR-3 cells, which express ER, IL-6 and IL-8 receptors, were suitable models for this study. Results We found that E2 not only enhanced IL-6/IL-8 secretion via NF-κB signaling pathway, but also modulated IL-6 and IL-8 receptors expression. Tamoxifen (Txf), an ER antagonist, completely abolished E2-stimulated IL-6/IL-8 expression. On the other hand, in the absence of estrogen, both cytokines increased ERα expression, decreased ERβ ex-pression, and activated estrogen-dependent transcriptional activation, which was completely blocked by Txf. Pretreatment of OVCAR-3 with p38 MAPK, MEK1/2 or ErbB2 MAPK inhihitors, respectively, IL-6-media-ted ER activation was blocked, while IL-8-indueed ER activation was blocked by Src inhibitor. Conclusion These data suggest that estrogen, IL-6 and IL-8 may form a mutual amplifying signaling which contributes to the growth and development of ovarian carcinoma.