Objective To discuss the clinical effect of entecavir in treatment of hepatitis B-related nephritis. Methods 28 patients with hepatitis B-related nephritis diagnosed in our hospital through needling biopsy of kidney from 2009 to 2012 were selected in this study. All patients were given oral entecavir, besides conprehensive treatments,including potassium aspartate and diammonium glycyrrhizinate. The treatment course was three months. We observed and analyzed patients' serum glutamic pyruvic transaminase, serum albumin and urine protein within 24 hours after two treatment courses.Results After one treatment course, the overall effective rate was 82.14%. Two courses later, the overall effective rate was 96.43%. Patients' serum glutamic pyruvic transaminase, serum albumin and urine protein within 24 hours after two treatment courses had significant differences with those before treatment's,the difference had statistical significance ( <0.05),but serum creatinine had no significant change after treatment. Conclusion Entecavir has significant curative effect on hepatitis B-related nephritis.

Fracture Fixation ; methods ; trends ; Fractures, Bone ; surgery ; Humans ; Pelvic Bones ; injuries ; surgery

China ; Humans ; Occupational Diseases ; prevention & control ; Occupational Health ; legislation & jurisprudence ; Occupational Health Services ; organization & administration ; standards

The clinical application of POCT technology is growing wider,the most significant advantage of this technology is to get the test results quickly,Therefore clinicians could make clinical decisions in time and choose appropriate approaches or interventions.However,it should be taken seriously that while POCT helps patients to get medical care successfully,the potential harm to the patients cannot be ignored.Hence it is essential that normative documents should be imposed as soon as possible.The technology of POCT can benefit the entire society only if the proper administration to approve the use of POCT technology is taken control of; the comprehensive and normative quality management is implemented,and the appropriate training to the related clinicians and nurses is enforced.

Objective To study the effectiveness of alkaline electrolyzed water (AEW)in the cleaning of medical instruments and its corrosive effect on metal. Methods Medical instruments of solid smooth,solid with gear or tube were cleaned with AEW adding ultrasonic washing,cleaning efficacy were compared with conventional method, AEW without pulsing ultrasonic washing and control group,corrosive effect of AEW on metal immersed in AEW was tested. Results Cleaning efficacy of solid smooth,solid with gear or tube instruments were significantly differ-ent among four groups(F= 10.868,14.268,6.146,respectively,all P<0.05). For solid smooth instruments, cleaning with AEW adding ultrasonic and cleaning without ultrasonic had a better effect than conventional cleaning (both P<0.005);For solid with gear instruments,AEW adding ultrasonic cleaning obviously had a better effect than conventional cleaning and AEW without ultrasonic cleaning(both P<0.001 );For tube instruments,cleaning efficacy of three cleaning methods were not significantly different (all P>0.05). AEW had no corrosive effect on stainless steel and copper. Conclusion The cleaning efficacy of AEW on solid smooth,solid with gear instruments is su-perior to conventional cleaning method,and can achieve better effectiveness if ultrasonic cleaning is added.

Objective: To explore the traditional Chinese medicine (TCM) diagnosis and treatment of type 2 diabetes in Tianjin urban population. Methods: A cross-sectional study was conducted on hospital patients with type 2 diabetes in TCM hospitals of different levels in Tianjin from 2003 to 2007. The multiphasic stratified cluster sampling method was adopted in selecting the target hospital. Finally 3 496 patients were selected as the survey sample. Then the constituent ratios of diabetes in different syndrome types were calculated. Results: In this study, the descending sort proportion of TCM syndrome types of type 2 diabetes in Tianjin urban population was deficiency of both qi and yin, stagnation of phlegm-dampness, exuberant heat due to yin deficiency, deficiency of both yin and yang, and blood stasis and qi stagnation. Most of the diabetes patients with deficiency of both qi and yin, deficiency of both yin and yang, and stagnation of phlegm-dampness were older than 60 years. Most of the diabetes patients with exuberant heat due to yin deficiency were 50 to 59 years old, while the diabetes patients with blood stasis and qi stagnation were 40 to 49 years old. The frequency of Danggui (Angelica sinensis) use was high in the diabetes patients with deficiency of both qi and yin; the frequency of Chenpi (Citrus reticulate Blanco) use was high in the diabetes patients with exuberant heat due to yin deficiency; the frequency of Baishao (Radix Paeoniae Alba) use was high in the diabetes patients with deficiency of both qi and yin; the frequency of Gancao (Radix Glycyrrhizae) use was high in the diabetes patients with stagnation of phlegm-dampness; and the frequency of Xingren (Semen Armeniacae) use was high in the diabetes patients with blood stasis and qi stagnation. Conclusion: The main syndrome types of diabetes patients in Tianjin urban area are deficiency of both qi and yin, stagnation of phlegm-dampness and exuberant heat due to yin deficiency. And the patients are mainly older than 50 years. The most frequently used herbs are Danggui (Angelica sinensis), Chenpi (Citrus reticulate Blanco), Baishao (Radix Paeoniae Alba), Gancao (Radix Glycyrrhizae) and Xingren (Semen Armeniacae).

A simple and reliable procedure for the isolation of pure DNA from human fetal liver is described.A high pure and natural DNA with an average molecular weight of 4 ?106 can be easily obtained after the sample is treated with SDS and trypsin and fractionated by a sepharose 4B column.The product meets the requirement for general research work of molecular biology.

Systems Biology including Systems Biomedicine is emerging internationally and providing opportunities for revolutions of Traditional Chinese Medicine (TCM) and conventional western drugs (WD), while the latter has been taking more advantages because WD has much stronger research basis at molecular levels than TCM. Thorough understanding of molecular network including gene network would automatically induces design of WD into formula western drugs equipped with TCM philosophy, but such molecular formula drug is eventually one of the final aims of modernization of TCM. So TCM is facing big threats it never met. This situation requires a nationwide and international strategy with intelligence and resolution.

To embark on a standard,systematic and legal metrology work in grassroots medical units,it is recommended that the position of a full-time gauger should be set and more effort should be put into publicity and supervision of metrology law,which is an indispensable part of equipment management.[Chinese Medical Equipment Journal,2008,29(2):108-109]

Objective To investigate the clinical effects of posterior reduction and interbody fusion in the treatment of thoracolumbar fractures and dislocations ,and its impact on the neural function .Methods 12 cases with thoracolumbar fractures and dislocations were treated with posterior reduction and interbody fusion .After treatment , flange height ,Cobb angle ,nerve function ,complications of internal fixation were observed ,and the clinical efficacy was evaluated.Results The anterior height of fractured vertebrae was significantly increased from (56.7 ±7.9)% to (90.4 ±9.8)% in 12 patients(t=9.3,P<0.05);Cobb angle was significantly reduced from (28.4 ±3.8)°to (7.9 ±2.9)°(t=14.9,P<0.05);The grade of neural function was obviously improved (from 2 cases A,5 cases B, 4 cases C and 1 case D to 1 case A,1 case B,2 cases C,6 cases D and 2 cases E),and there were no serious compli-cations.Conclusion The clinical effect of posterior reduction and interbody fusion in the treatment of thoracolumbar fractures and dislocations was good ,which is worthy of clinical application .