1.A NEW TYPE HALF—LENGTH CARDIO—PULMO NARY RESUSCITATION TRAINING MODEL
Chinese Medical Equipment Journal 1989;0(01):-
The present article introduces a cardiopulmonary resuscitation model haif- length above the cross-section at the level of sixth rib.It wad designed on the basis of normal human antomy with lifelike configuration of heart,lungs,and some other organs.Synchronous pulsation of carotid artery could be detected during extracorporal cardiac massage,The accuracy of massage technique could be displayed by red and green coloured bulbs.A ninety-degree overextension of the neck is maintained during artificial respiration.Its function allows expansion of both the thorax and the lungs,lt is suitable for teaching in medical university and college and trining of first-aid personnel.
2.Effects of recipe for invigorating kidney on expression of estrogen receptors in ovariectomized rats
Wenbin YANG ; Wenjian WANG ; Zhenyu FEI
Journal of Integrative Medicine 2006;4(1):26-9
OBJECTIVE: To observe the effects of recipe for invigorating kidney on expression of estrogen receptors in ovariectomized rats. METHODS: The rats, which were given high-cholesterol diet after ovariectomy, were chosen as experimental subjects. After fed kidney-invigorating recipe for 16 weeks, the rats were killed and the levels of serum lipid and estradiol of these rats were examined. The expressions of estrogen receptor alpha and beta mRNAs in aorta, pituitary gland and hypothalamus, and the affinity of estrogen receptor-ligand were also detected. RESULTS: The kidney-invigorating recipe could increase the expression levels of estrogen receptor alpha and beta mRNAs in different parts such as aorta, pituitary gland and hypothalamus, and enhance the affinity of estrogen receptor-ligands. CONCLUSION: The recipe for invigorating kidney may meliorate atherosclerosis in ovariectomized rats by regulating the estrogen receptors.
3.Screening antigen epitope of bFGF by phage display
Junrjian XIANG ; Zhenyu ZHONG ; Hongyu YANG
Chinese Journal of Immunology 1985;0(02):-
Objective:To investigate the epitope and its immunogenicity of bFGF. Methods -.The phage disply 7 peptides library was screened with monoclonal antibody GE22 to bFGF, which neutralize the bioactivin'es of bFGF. Results: After three cycles screening, the isolated phage clones with GF22 epitopes specifically inhibited bFGF binding to GF22.Sequence analysis showd that the epitopes shared a highly consensus spequence( Leu-Pro-Pro/Leu-Gly-His-Phe/He-Lys) and PPGHFK sequence was located at aino acids 22-27 (PPGHFK) within bFGF (155aa) molecule.Phage clones with the epitopes could highly induce imuno-response in mice,eapically with the sequence LPLGHK was 3 times higher than original sequence. Conclusion:Trie sequence LPLGHK may be a valuable vaccine in future studies of bFGF.
4.Clinical significance of preventive treatment of thrombosis for patients undergoing gynecological surgery with high risk factors
Bailiu YANG ; Zhenyu ZHANG ; Shuli GUO
Chinese Journal of Obstetrics and Gynecology 2009;44(8):570-573
e factors of elder age, abdominal surgeries and malignant tumor.
5.Lung adenocarcinoma progression schema
Zhenyu YANG ; Zhiwen FAN ; Lei ZHANG
Journal of International Oncology 2013;(2):120-122
Lung adenocarcinoma is usually thought to follow a linear multistep progression schema,that is precancerous lesions progress to adenocarcinoma in situ,and progress to micro-invasive adenocarcinoma,eventually some lung adenocarcinoma happen diffusion.However,recent findings reveal that this linear progression schema might not occur in all lung adenocarcinoma subtypes,and some subtypes show a kind of non-linear progression schema.The study of these two kinds of schemas can help for early detection of lung adenocarcinoma.
6.Curative Effect of Herbal Desensitizer in the Treatment of Dentine Hypersensitivity
Zhenyu TANG ; Weiyi ZHANG ; Suqin YANG
China Pharmacy 2005;0(24):-
OBJECTIVE:To observe the clinical efficacy of herbal desensitizer in the treatment of dentine hypersensitivity. METHODS: 126 patients with dentine hypersensitivity were enrolled: 64(a total of 172 diseased teeth) were randomly assigned to trial group to be treated with herbal desensitizer,and 62(158 diseased teeth) to control group to be treated with sodium fluoride glycerin. The clinical effects observation was scheduled immediately,3 and 6 months after the treatment. Then the results were analyzed using statistics software.RESULTS: Significant differences were found between the trial group and the control group in clinical effects (P
7.Reference from the Fair PharmaCare Program of BC Canada
Zhenyu YANG ; Min YAN ; Guozhu LIU
China Pharmacy 2001;0(10):-
OBJECTIVE:To introduce the Fair PharmaCare program of BC Canada for the reference of the reform of China's medical insurance system.METHODS:The running procedure of Fair PharmaCare program of BC Canada was introduced in detail and its characteristics were analyzed.RESULTS & CONCLUSIONS:Fair PharmaCare program covers all BC residents and protects them against economic difficulties in pharmacare.The program serves as a reference for the reform of China's medical insurance system.
8.The study of anti-tumor genecity effect of human IL-10 antisense and viral IL-10 antisense on nasopharyngeal carcinoma cells
Jianping TAO ; Kun YANG ; Zhenyu ZHU
Chinese Journal of Immunology 2000;0(08):-
Objective: To study the effectiveness of anti-tumorgenecity of human IL-10 antisense and viral IL-10 antisense on nasopharyn-geal carcinoma(NPC) cells.Methods:Human IL-10 cDNA and viral IL-10 gene had been amplifed and cloned. A two-valent eukaryotic expression vector for antisense nucleic acids of human IL-10 cDNA and viral IL-10 gene had been constructed and designated as pcDNA3/AS hIL-10 + AS vIL-10.The recombinant vector was transfected into a NPC-clerived cell strain-SUNE cells. After that, the transfected and nontransfected SUNE cells were inoculated i.d. in the right flank of SCID mice and hu-PBL-SCID mice to evaluate their tumorgenecity changes.Results:The results of ELISA analysis showed that the concentration of hIL-10 and vIL-10 was 242 ?3 pg'ml-1 in supernatant of the nontransfected SUNE cells, and onry 22 ? pg ?ml-1 of hIL-10 and vIL-10 contained in supernatant of the transfected SUNE cells. After inoculation to SCID mice, the transfected and nontransfected SUNE cell showed the same growth manner. But inoculating to hu-PBL-SCID mice, the transfected SUNE cells grew slowerly than the nontransfected SUNE cell. With statistical analysis, the size and mean weight of the tumors from the hu-PBL-SCID mice inoculated with transfected SUNE cells were significantly lower in contrast to that from the hu-PBL-SCID mice inoculated with nontransfected SUNE cells( P
9.Endoscopic-Assisted Correction of Facial Contour Deformities
Xiaoping CHEN ; Jie LIN ; Zhenyu YANG
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To evaluate the efficacy of endoscopic techniques for corrections of facial contour deformities.MethodsA total of 58 patients(48 women and 10 men)with square face(38),prominent zygoma(12),or crooked noses(8)were treated by endoscopic-assisted technique in our hospital.Results The operation time ranged from 40 to 86 min(mean,65 min),and intraoperative blood loss was 60-120 ml(mean,78 ml).The patients were discharged from the hospital in 3 to 7 days(mean 4)after the surgery,and was followed up for 3 to 24 months.During the period,no one had unexpected fracture,injuries to the mental and facial nerves and vessels,or infection.All the patients were satisfied with the surgical outcomes.ConclusionsEndoscopic-assisted correction of facial contour deformities is feasible,safe,and effective.
10.Aassociation between gene polymorphism of interleukin-4 C590T and serum level of interleukin-4 and atherothrombotic cerebral infarction
Zhenyu TANG ; Qidong YANG ; Lin ZHOU
Journal of Clinical Neurology 1988;0(02):-
Objective To explore the association between gene polymorphism of interleukin(IL)-4 C590T and serum level of IL-4 and atherothrombotic cerebral infarction(ATCI).Methods The gene polymorphisms of IL-4 C590T in 159 patients with ATCI and 151 normal control subjects were carried out by polymerase chain reaction(PCR)-restriction fragment length polymorphism(RFLP).The serum level of IL-4 in normal control group was determined with enzyme linked immunosorbent assay(ELISA) method.Results In the normal control group,the serum level of IL-4 in TT genotype[(31.85?5.68) pg/ml] was higher significantly than those in TC[(28.67?6.00) pg/ml] and CC genotypes[(20.98?0.99) pg/ml],TC genotype was higher significantly than CC genotype(all P0.05).Conclusions IL-4 590T allele is associated with higher level of serum IL-4.The C590T polymorphism is not associated with the incidence of ATCI.