1.Efficacy Observation of Sanjin Granules in the Treatment of Residual Stones after Extracorporeal Shock Wave Lithotripsy
Zhenqiu PENG ; Weiwei XIN ; Shaofei WU
China Pharmacy 2015;(20):2838-2839,2840
OBJECTIVE:To observe therapeutic efficacy of Sanjin granules in the treatment of residual stones after extracorpo-real shock wave lithotripsy(ESWL). METHODS:72 patients with residual stones after ESWL were selected and randomly divided into group A and B with 36 cases in each. Patients in group A were given Sanjin granules with warm water,2 times/d,20g/time;B group were treated with conventional therapy as drinking more water combined with jumping movement. Therapeutic efficacies of two groups were observed after 4 and 8 weeks of treatment. RESULTS:After 4 weeks treatment,the total effective rate was 33.33% in group A and 13.89% in group B,there was statistically significant difference(P<0.05);After 8 weeks treatment,the total effective rate was 63.89% in group A and 19.44% in group B,there was statistically significant difference(P<0.05). CON-CLUSIONS:Sanjin granules can pass the residual gallstones after ESWL effectively,showing a significant therapeutic efficacy.
2.Multilevel models analysis on influencing factors of overweight and obesity in the elderly from Changsha city
Yongquan LIU ; Zhen PENG ; Biao ZENG ; Zhenqiu SUN
Chinese Journal of Geriatrics 2012;(12):1120-1123
Objective To investigate the current situation and influencing factors of overweight and obesity in the elderly from Changsha city.Methods Using stratified sampling,2500 elderly in Changsha were included for the investigation by questionnaire and physical examination.The influencing factors were analyzed with univariate analysis and two-level models.Results Among 2500 persons,the valid questionnaires were 2254,the effective rate was 90.16%.About 39.71% (895/2254) of Changsha's elderly were in overweight and obesity (BMI≥ 24 kg/m2).Univariate analysis showed that there were significant differences in BMI among different area,education degree,income,marital status,drinking wine,drinking tea,physical exercises and occupation (x2= 304.17,18.39,19.35,12.93,13.29,11.77,12.87,12.84,all P<0.05).The results of two-level models indicated that the independent influencing factors were income,physical exercises,drinking wine,age and occupation.Conclusions It is necessary to take interventional measures against elderly obesity and to encourage the elderly taking physical exercises and keeping reasonable diets.
3.Employment-related anxiety and depression in senior college students in China
Minning PENG ; Guoqing HU ; Jing DONG ; Lingling ZHANG ; Binbin LIU ; Zhenqiu SUN
Journal of Central South University(Medical Sciences) 2010;35(3):194-202
Objective To examine the association of employment-related events with depression and anxiety in senior college students in China.Methods Altogether 1321 senior college students were recruited from Central South University and the survey was administered anonymously. Anxiety and depression were assessed with the Self-rating Anxiety Scale (SAS) and the Center for Epidemiologic Studies Depression Scale (CES-D), respectively. Employment-related events were reflected by the employment-related options when students were surveyed. Logistic regression was used to estimate the effect of employment-related events on anxiety and depression.Results We collected 1178 valid questionnaires. Taking 50 and 16 as the cutting-point of SAS and CES-D, we found 18.9% and 55.4% of the participants showed symptoms of anxiety and depression, respectively. After controlling confounding factors, those students who had taken the entrance exam of graduate schools and were optimistic for the result, those who had taken the entrance exam of graduate schools but were pessimistic for the result, and those who neither took the entrance exam of graduate schools nor received a job offer, had a higher risk of anxiety than those who would attend a graduate school without exam, and the odds ratios were 2.5, 2.3, and 3.5, respectively. For students' depression, the odds ratios of the three categories mentioned above were 2.0, 1.5, and 2.6, respectively. Conclusion Senior college students who face bad employment-related events are at a higher risk of anxiety and depression.
4.Comparison of the diagnostic and therapeutic strategies for patients with benign prostatic hyperplasia between doctors in general hospitals and community hospitals in urban China
Minxue SHEN ; Ming HU ; Fang YANG ; Na ZENG ; Zhen PENG ; Zhenqiu SUN ; Jingcheng SHI
Chinese Journal of Geriatrics 2013;32(10):1123-1127
Objective To comparing the diagnostic and therapeutic strategies for patients with benign prostatic hyperplasia(BPH) between doctors in general hospitals and community hospitals,and to provide scientific clues for the standardization in medical practice.Methods General and community hospitals in urban China were selected via the stratified sampling.127,325 outpatients in these hospitals from December 2011 to December 2012 were randomly recruited.Results The average age of patients was(67.82±8.62) years.There were significant differences in I-PSS,prostate volume,urinary flow rate(UFR) and result of digital rectal examination(DRE) between patients in general and community hospitals.The rates of diagnostic applications were different between doctors in the two kinds of hospitals except I-PSS.Compared with community hospitals,DRE was more frequently applied while ultrasonic inspection and UFR test were less used in general hospitals in North China.A totally opposite situation was observed in East China as compared with the north.The application rates of DRE and UFR test were lower and ultrasonic inspection rate was higher in community hospitals than in general hospitals in South China.Pharmacotherapy was the most common treatment for BPH patients in both types of hospitals(97.53 %).The rates of drug combinations were statistically different but both were close to 75% in the two types of hospitals.In community hospitals,the percentage of patients receiving watchful waiting with severe symptoms and signs were lower than that of patients receiving watchful waiting with moderate symptoms and signs,but the percentage of patients receiving operation was not significantly increased.On the contrary,the percentage of patients receiving operation with severe symptoms and signs was higher than that of patients receiving operation with moderate symptoms and signs in general hospitals,but the percentage of patients receiving watchful waiting was not decreased.Conclusions Applications of diagnostic methods are significantly different between doctors in general hospitals and community hospitals and vary among regions.Therapeutic strategies are correlated with the severity of obstructive symptoms or signs.The medication strategy is similar between the two types of doctors.
5.Temporal and spatial distribution as well as prediction model of sexually transmitted diseases in elderly men in Shenzhen
Yufeng HU ; Zhenqiu SUN ; Fuchang HONG ; Lina LAN ; Peng PAN ; Yanshi MO ; Yumao CAI ; Lizhang WEN ; Tiejian FENG
Chinese Journal of Geriatrics 2010;29(5):397-400
Objective To analyze the status quo of sexually transmitted diseases (STDs) of the elderly in recent years in Shenzhen, to explore the characteristics of temporal and spatial distribution,and to establish prediction model of STDs of the elderly in Shenzhen. MethodsUsing the surveillance system data of STDs from 2005 to 2009 in Shenzhen city, the incidence, temporal and spatial distribution of syphilis and gonorrhea were analyzed in the elderly aged 50 years and over by SaTScan. The incidence prediction model of STDs was established by Eviews 5.0.Results (1)The incidences of the two kinds of STDs from 2005 to 2009 in Shenzhen were on the rise and on more marked increase in male than in female. The rising velocity in over-60 year age group was similar with in 50-59 year age group. The rising velocity of syphilis was faster than gonorrhea. (2)The space-time distribution analysis showed there were clusters of the STDs in elderly men in 2005 in Lianhua and Meilin districts (P = 0. 026, RR= 2.13). (3) ARIMA (0, 1,1) (0,0, 1) 12 model was a suitable forecasting model for STDs in elderly men in Shenzhen. Conclusions
6.Comparison of clinical efficacy and safety of two kinds of surgical method in the treatment of mixed hemorrhoids for Ⅲ~Ⅳstage combined with internal rectal mucosal prolapsed
Shubang FAN ; Zhenqiu PENG ; Zhuomin YE ; Xiaomei WU
Chinese Journal of Primary Medicine and Pharmacy 2018;25(19):2549-2552
Objective To compare the clinical efficacy and safety of two kinds of surgical method including Milligan-Morgan haemorrhoidectomy and automatic ligation of hemorrhoids in the treatment of mixed hemorrhoids forⅢ-Ⅳstage combined with internal rectal mucosal prolapse.Methods From March 2013 to July 2015,100 patients with mixed hemorrhoids for Ⅲ-Ⅳstage combined with internal rectal mucosal prolapse were chosen in the Traditional Chinese Medicine Hospital of Qingyuan County,and they were randomly divided into two groups according to the digital table,with 50 patients in each group.A group received Milligan-Morgan haemorrhoidectomy,and B group received automatic ligation of hemorrhoids.The clinical effect,the level of clinical indicators in peri-operative period,the scores of pain,bleeding,anal edema and dysuria after treatment and the skin tag formation rate of the two groups were compared.Results The short-term effective rates of A group and B group were 76.00%,96.00%,respectively.The clinical effect of B group was better than that of A group,and the difference was statistically significant(χ2 =7.73,P<0.05).The operation time,blood loss volume,wound healing time and total hospitalization time of A group were(20.97 ±4.52)min,(12.47 ±1.65)mL,(25.48 ±3.76)d,(15.55 ±4.38)d,respectively,which of B group were(12.01 ±2.54)min,(7.29 ±1.02)mL,(20.24 ±2.18)d,(12.02 ±3.82)d,respectively.The levels of clinical indicators in peri-operative period of B group were better than those of A group,and the differences were statistically significant(t=2.74,3.02,2.84,3.46,all P<0.05).The scores of pain,bleeding,anal edema and dysuria after treatment of B group were lower than those in A group and before treatment,the differences were statistically significant(t=2.67,2.50,3.04,2.76,all P<0.05).The skin tag formation rate of B group was lower than that of A group and before treatment,and the difference was statistically significant(χ2 =8.77,P<0.05).Conclusion Com-pared with Milligan-Morgan haemorrhoidectomy,automatic ligation of hemorrhoids in the treatment of mixed hemorrhoids for III-IV stage combined with internal rectal mucosal prolapse can efficiently relieve the clinical symptoms and signs,promote wound healing and is helpful to reduce the postoperative complications risk.
7.Serum adiponectin, leptin level, and bone mineral density in postmenopausal women.
Xianyang LEI ; Xiaoding PENG ; Nan WU ; Ming HU ; Zhenqiu SUN
Journal of Central South University(Medical Sciences) 2009;34(6):559-562
OBJECTIVE:
To determine whether serum adipocytokines and leptin level are associated with bone mineral density (BMD) in postmenopausal women.
METHODS:
Serum adiponectin and leptin level were measured by ELISA in 336 postmenopausal women. BMD was measured by dual energy X-ray absorptiometry (DXA) at the whole body, lumbar spine, hip, and forearm. Body compositions including lean tissue mass and body fat mass were measured by DXA, and their relationship was analyzed.
RESULTS:
Serum adiponectin levels were negatively related to BMD at the whole body, the lumbar spine, the hip, and the forearm (r = -0.181, r = -0.208, r = -0.228, r = -0.203, and P < 0.05, respectively). After adjustment for age and fat mass, the correlation with BMD still remained (r = -0.131, r = -0.140, r = -0.159, r = -0.172, and P<0.05, respectively). Serum leptin levels were positively related to BMD was at the hip and the forearm (r = 0.162, r = 0.210, and P < 0.05, respectively). After adjustment for age and fat mass, the correlation with BMD at the forearm remained (r = 0.157, P<0.05), but the correlation with BMD at the hip disappeared. In the multiple linear stepwise regression analysis, year since menopause, lean mass, adiponectin, and estradiol were independent predictors of BMD at the body, the hip and the forearm; year since menopause, lean mass, body mass index, adiponectin, and extradiol were independent predictors of BMD at the lumbar spine.
CONCLUSION
Adiponectin is the independent predictor of BMD.
Absorptiometry, Photon
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Adiponectin
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blood
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Aged
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Aged, 80 and over
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Bone Density
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physiology
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Enzyme-Linked Immunosorbent Assay
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Female
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Humans
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Leptin
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blood
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Middle Aged
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Postmenopause
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blood
;
metabolism
8.Effect of nutrition and food safety education among middle school students in a poverty-stricken county in west China.
Donghong HUANG ; Zhenqiu SUN ; Jingxuan HU ; Minxue SHEN ; Zhen PENG ; Na ZENG
Journal of Central South University(Medical Sciences) 2014;39(3):313-319
OBJECTIVE:
To evaluate the effect of nutrition and food safety education among middle school students in a poverty-stricken county in west China, and to explore the better education model for further education.
METHODS:
Students of grade 7 to 9 were selected from 4 middle schools in the country through multi-stage cluster sampling for the questionnaire, and the schools were assigned into an intervention group or a control group. After students in the intervention schools completed one year nutrition and food safety education with the textbooks, students were chosen from the same 4 schools to finish the same questionnaire again.
RESULTS:
A total of 410 students from grade 7 to 9 were selected at the baseline study, and 474 students in the final study. The essential characteristics of the 2 groups were not statistically significant (P>0.05). In the baseline investigation, the differences in the scores on nutrition and food safety knowledge, attitude and practice between the 2 groups were not significant (P>0.05). In the final study, the scores on the knowledge, attitude of nutrition knowledge learning, and dietary habits among students in the intervention group were significantly higher than those in the control group (P<0.05). School-students mixed model demonstrated that the intervention was protective factor on scores of knowledge, in particular with nutrition related diseases and reasonable diet (P<0.05). But the intervention didn't affect the scores on attitude in both ways (P>0.05).
CONCLUSION
Nutrition and food safety education can improve the nutrition and food safety knowledge effectively. The curriculum should be further standardized and different emphases should be set up to different grades to cultivate healthy diet behaviors.
China
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Diet
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Food Safety
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Health Education
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Health Knowledge, Attitudes, Practice
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Humans
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Nutritional Sciences
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education
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Poverty
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Schools
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Students
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Surveys and Questionnaires