Objective:To explore the current situation and influencing factors of forgiveness tendency of clinical nurses.Methods:This study was a cross-sectional survey. From September 2020 to March 2021, a total of 236 clinical nurses from 3 ClassⅢ Grade A hospitals in Yantai were selected by the convenient sampling method. General information questionnaire, the Heartland Forgiveness Scale (HFS) , the Chinese version of the Jefferson Scale of Physician Empathy (JSPE-HP) and Subjective Well-Being (SWB) were used for investigation. Single factor analysis and multiple linear regression analysis were used to analyze the influencing factors of forgiveness tendency of clinical nurses. At the same time, Pearson correlation analysis was used to explore the relationship between forgiveness tendency, empathy and overall well-being. In this study, a total of 236 questionnaires were issued and 227 valid questionnaires were returned. The effective response rate was 96.19%.Results:The total score of HFS of 227 clinical nurses was (113.21±6.94) . The results of multiple linear regression analysis showed that age, educational background, religious belief, empathy level and overall well-being were the main influencing factors of forgiveness tendency of clinical nurses ( P<0.05) . Conclusions:The level of forgiveness tendency of clinical nurses in this study is above medium level. It is necessary to focus on the clinical nurses with low nursing age, low education, low empathy and low happiness and carry out targeted intervention to improve the level of forgiveness tendency of clinical nurses, so as to improve the physical and mental health and nursing quality of clinical nurses.