23 cases of advanced malignant tumors of the aged and MOFare analysed It has been found that the sequences of MOF are lung, kidney, heart, liver, brain, gastro-intestine ard Dic, amounting to the average of 3.4 organs with a death rate of 100%. The results indicate that old people with advanced malignant tumors have very low immunity. The attack of organs by the primary and secondary tumors is the basic factor of MOF, and various infections are its precipitating factor. The incidence characteristics, prevention and treatment of the MOF are discussed.

Objective To investigate the MRI appearances of postpartum posterior reversible encephalopathy syndrome (PRES). Methods The clinical and radiological data of 8 patients with postpartum PRES were analyzed retrospectively, 5 cases were 1 week after postpartum,2 cases were 2 weeks afterpostpartum, 1 case was 4 weeks after postpartum. All cases underwent MRI examination, checking sequence included T,WI,T2WI,FLAIR,DWI,SWI, and 4 of them underwent MR venography (MRV). Results MRI showed basal bilaterally symmetrical distributions of lesions, mainly located in subcortex and cortex of cerebral hemisphere and predominantly in the occipital lobe,the lesions appeared as hyperintensity on FLAIR and T2WI,isointensity or mildly hypointensity on T1WI,hyperintensity on DWI. MRI in 8 patients demonstrated multiple lesions located in bilateral parietal lobe (8 cases),bilateral occipital lobe (8 cases), bilateral frontal lobe ( 4 cases ), bilateral temporal lobe (6 cases ), bilateral tempura-occipital lobe ( 8 cases),splenium of corpus callosum(l case), bilateral basal ganglia (l case), bilateral oval center( 1 case), bilateral cerebellar hemisphere (1 case), left frontal lobe hemorrhage (l case). Five patients' follow-up scan showed decreased or disappeared abnormal signals. Conclusion MRI examination scan identify the location, quality and degree, meanwhile, analyze the pathological foundation of postpartum PRES, which conduces to guiding treatment and preventing complication.

Chronic atrophic gastritis( CAG)is a commonly seen digestive tract disease with the histopathological findings of mucosa inflammation,gland atrophy,intestinal metaplasia and dysplasia. Intestinal metaplasia is considered as a typical sign of CAG. In recent years,with the rapid progress of endoscopic technique,new technology has been applied for the diagnosis of CAG. This article reviewed the advances in studies on ordinary endoscopy,narrow-band imaging technique,magnifying endoscopy,narrow-band imaging-magnifying endoscopy and confocal laser endomicroscopy for the diagnosis of CAG.

The paper describes the drawbacks of hospitals neglecting personnel centered management and sets forth ways of conducting such management. They include strengthening cultural construction, implementing impartial management, and setting good examples by leading officials.

Objective To explore the time-effectiveness of acupuncture in treating hypertensive intracerebral hemorrhage (HICH), and to find the best intervention time of acupuncture. Method The eligible HICH patients were randomized into a 2 d acupuncture group, a 7 d acupuncture group, and a 14 d acupuncture group. The National Institute of Health Stroke Scale (NIHSS) and Barthel Index (BI) were adopted for evaluation, and the clinical efficacies of acupuncture intervened at different time points for HICH were observed. Result The treatment efficacy of the 2 d acupuncture was better than that of the 7 d acupuncture group(P<0.05), and the treatment efficacy of the 7 d acupuncture group was better than that of the 14 d acupuncture group(P<0.05). There were no significant between-group differences in comparing the security indexes. Conclusion Acupuncture is safe and effective in treating HICH, and its efficacy is related to the intervention time, the earlier the better.

Objective To investigate the clinical effect of psychological intervention combined with milrinone on the treatment of the children with congenital heart disease complicated with severe pneumonia and heart failure. Methods In the First People's Hospital in Jining City from February 2015 to December 2016, 100 children with congenital heart disease complicated with severe pneumonia and heart failure as the research object, randomly divided into the control group and the experimental group, 50 cases in each group. The control group were received routine treatment, including ECG monitoring, anti infection and oxygen therapy,and the treatment of rice farmers. The experimental group was treated with milrinone treatment, psychological intervention, pay attention to the mental health of patients. The therapeutic effects of the experimental group and the control group were compared and analyzed. Results after the corresponding treatment, the patients in the experimental group and the control group were mild and no serious adverse reactions occurred. There was no significant difference in the incidence of adverse reactions between the two groups, and there was no statistical significance. The experimental group of patients with respiratory stabilization time is (1.76±0.32) days, to eliminate irritability (7.12±1.12) hours, heart rate recovery time (1.82±0.74) days, pulmonary rales disappeared time was (8.12±1.41) days. The clinical symptoms of the patients in the control group were significantly longer than those in the experimental group, with statistical difference (P<0.05). Conclusion The effective rate about psychological intervention combined with milrinone on the treatment of the children with congenital heart disease complicated with severe pneumonia and heart failure is high, which is worthy of clinical application.

Objective To explore the use of lamivudine alone induced the poor response,especially the related factors of the occurrence of YMDD.Methods Retrospective analysis of 160 cases of the poor answering cases after lamivudine treatment,the baseline parameter values,the time appearing to the poor answering and the HBVDNA load in treatment were analyzed,to study their relationship with poor response.Results The lamivudine prolonged,the poor response to the probability gradually increase.The mutation rate in the 12nd month was 19.67％ and in the 36th month was 49.18％ ( P ＜ 0.05 ).Response to the many reasons,the YMDD mutation is the more common one.The relationship among HBVDNA load,ALT level on baseline and the rate of poor response emergence,the YMDD mutation rate was clear.By comparison in groups,the difference was significant (P＜0.05).Conclusion The lower baselins of ALT level,the higher of HBVDNA load,the greater probability of the poor response and the YMDD mutation.

Objective To study the epidemiological characteristics of diarrhea-predominant irritable bowel syndrome (IBS-D) as well as the relationship between the main syndromes and different factors. Method The relevant information of patients were collected by clinical epidemiological method and the relationship between the main characteristics of the IBS-D syndromes and different factors was explored with the major syndromes as the key link. Result Most of the cases aged 30～49 years old. Special hobbies of patients followed by drinking, smoking, addicting spicy, addicting coffee and so on. Poor emotion, mental stress and diet were the main inducements. Liver stagnation and spleen deficiency has the highest percentage (44.7%). The distribution of syndromes in different ages, different genders, different occupations and different education had no significant difference. Conclusion The number of IBS-D hospital visiting-patients is lower than the actual number of illness people. Mental factors are important internal factors, and dietary factors may be an important external factor. Different factors have no effect on the distribution of syndromes.

Objective To evaluate the effects and the side effects of three-dimensional conformal radiotherapy on recurrent cervical carcinoma with pelvic wall infiltration. Methods Twenty-one patients with recurrent cervical carcinoma infiltrating the pelvic wall were irradiated by three-dimensional conformal radiotherapy. The regimen was: total dose 30-52Gy,5-8.5Gy/f, 1f/2d. Results The rates of sciatic pain and leg edema relief response were 100 % and 61 % respectively. The CR+PR response rate was 71.4 %. The overall 1-, 2- and 3-year survival rates were 38 %, 14 % and 4 %. Conclusion Three-dimensional conformal radiotherapy is more effective than conventional radiotherapy and chemotherapy for recurrent cervical carcinoma infiltrating the pelvic wall. It doesn't increase the side-effects on the digestive system and the urinary system.

Objective To know the drinking water quality in the rural areas in Fujian Province in order to provide the scientific basis for water improvement in the rural areas.Methods Fourteen counties were selected in Fujian,2004,10 monitoring sites in each county based on the population proportion of different drinking water types.Sixteen indicators were determined for every water sample.Results In the 14 investigated counties,38.71% of total population drinking water supplied with surface water,and 61.29% with ground water source.Drinking water from centralized water supply system was supplied to 58.24% of total population.The qualified rate of water samples was 26.39% for total 288 water samples,35.38% for surface water samples and 18.99% for ground water samples respectively.The hygienic state of surface water was much better(P