1.Observation of pulmonary artery motion curve with anatomical M-mode echocardiography and analysis of influential factors
Chinese Journal of Medical Imaging Technology 2009;25(7):1192-1194
Objective To observe the pulmonary artery motion curve with anatomical M-mode echocardiography, and to investigate its influential factors. Methods The pulmonary artery motion curve was detected and pulsating amplitude of pulmonary artery wall (PAWPA) was measured with anatomical M-mode echocardiography in 160 patients with normal pulmonary artery pressure. Intraclass correlation coefficient (ICC) was used to assess inter-observer conisitency of PAWPA measurements between two investigators who were blinded to each other's findings, and intra-observer consistency of PAWPA with repeating the measurements on two occasions by the same investigator in 20 randomly selected cases. Stepwise multiple regression was used to analyze the following potential influential factors of PAWPA: age, gender, heart rate, blood pressure, atherosclerosis, right atrial diameter, and pulmonary insufficiency. Results There was good consistency between two independent observers' measurements and between two occasions in the same observer's measurements for PAWPA with ICC values of 0.91 (95% CI, 0.37-0.99) and 0.95 (95% CI, 0.60-0.99), respectively. PAWPA was negatively correlated with age (β=-0.47, P<0.001) and heart rate (β=-0.29, P<0.005). There was no correlation of PAWPA with gender, blood pressure, atherosclerosis, right atrial diameter, and pulmonary insufficiency. Conclusion Anatomical M-mode echocardiography can be used for measuring PAWPA with good consistency and reproducibility. In normal pulmonary artery pressure cases, PAWPA is affected by age and heart rate.
2.Stability of Cefoxitin Sodium for Injection Compatible with Metronidazole Injection Fluid
Zhenhua HUANG ; Yunying HUANG ; Heming HUANG ; Limin HUANG
China Pharmacy 2001;0(08):-
OBJECTIVE:To evaluate the stability of cefoxitin sodium for injection compatible with metronidazole injection fluid.METHODS:Cefoxitin sodium for injection was compatible with metronidazole injection fluid and the solution was stored ordinary temperature for4hours,the maximum absorption peak and absorbance of the solution were determined by UV,and the color of the solution was observed,and its pH value was determined.RESULTS:There were no significant changes in absorp-tion peak,absorbance,color and pH value of the compatible solution.CONCLUSION:Cefoxitin sodium for injection is com-patible with metronidazole injection fluid,and the compatible solution remains stable at ordinary temperature for4hours.
3.A follow-up investigation on the surgical operations of 84 cases of femoral condylar fracture
Zhenhua OUYANG ; Xianli LIU ; Bin HUANG
Chinese Journal of Orthopaedic Trauma 2004;0(06):-
Objective To investigate the effects of surgical operations on different femoral condylar fractures. Methods A retrospective study was carried out on surgical operations of 84 patients with different femoral condylar fractures. The healing of fracture, functional recovery of knee joint and complications were analyzed. Results All the fractures healed in 6 to 12 months. According to Karlstrom's knee function score system, 48 knees were rated as excellent, 20 good, 13 fair, and 3 poor. The total good and excellent rate was 80.9%. Conclusions Anatomical reduction, secure fixation, timely treatment of complicated damage, and early rehabilitation exercise are important in treatment of femoral condylar fracture. The sustain blade plate is recommendable, because its design suits the anatomical structure of femoral condylar, and it not only provides convenient and stable fixation but also allows early postoperative functional training.
4.Primarily reconstruction for the scalp,skull and dura defects of type D craniopagus
Huawei JIN ; Quan HUANG ; Zhenhua YU
Chinese Journal of Microsurgery 2000;0(02):-
Objective To discuss the methods of primarily repairing scalp,skull and dura defects of separated type D craniopagus Methods The huge defects in craniopagus was primarily repaired by the application of scalp expander, transferring scalp flap, repairing dura with pedicle periosteums, repairing skull defects with Titanium plates Results The survival baby has a good sharp of skull and well healing of scalp postoperatively Conclusions Defects of separated type D craniopagus can be primarily repaired
5.The Cross-section Study on the Obesity and Hypertension in Children Aged 6 to 12 yrs,in Shenzhen
Cai HUANG ; Zhenhua XIE ; Chenggang YE
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(03):-
Objective To investigate the prevalence of hypertension and obesity and their main influencial factors among 6~12 years old children in Shenzhen.Method 1 140 children aged from 6 to 12 years old in 4 schools in Shenzhen were sampled by random cluster sampling,and their systolic blood pressure(SBP),diastolic blood pressure(DBP),body height,weight and other morphological parameters were measured.Results The prevalent rate of hypertension was 9.4%(8.6% for boys and 10.2% for girls);Rate of overweight and obesity for boys were 13.25% and 13.72,respectively,and the girl were 9.09% and 8.10%,respectively.There were a increasing trend toward SBP and DBP with age,especially SBP.After adjusted with age and gender,the partial correlation coefficients between BMI and SBP,DBP were 0.462 and 0.357,respectively(P
6.Treatment of unstable angina pectoris using low molecular weight heparin
Zhenhua HUANG ; Wenmin ZHU ; Xuemei TANG
Clinical Medicine of China 1999;0(02):-
Objective To observe the treatment effect of low molecular weight heparin (LMWH) in the treatment of unstable angina pectoris.Methods LMWH (0.4~0.6 ml Bid) was used through subcutaneous injection in 36 cases of unstable angina pectoris for 14 days on end.Results The clinical effective rate was 66.67%.The drug was effective in the decreasing of the frequency and time of angina pectoris,and also in the decreasing of nitroglycerin consumption as well as in the improvement of the scope and severity of cardiac ischemia by ECG.Conclusion LMWH is an effective and safe drug for the treatment of unstable angina pectoris.
7.Advances in stroke genetics
Zhenhua HUANG ; Hui ZHENG ; Zhen DENG ; Suyue PAN
International Journal of Cerebrovascular Diseases 2011;19(7):481-487
Stroke is an important public health problem both in China and worldwide.Stroke genetics research has made great progress in recent years, especially the genome-wide association study (GWAS) and the emergence of epigenetics, has brought a breakthrough in this field. They studied the pathogenesis of stroke from the genetic level and the environmental factor levels. Although there are still many problems to be solved, the prospect of stroke genetics is bright.
8.Humanistic spirit cultivation of the medical students during the clinical internship
Yajun QIAO ; Heqing HUANG ; Kangning CHEN ; Yihong WU ; Zhenhua ZHOU
Chinese Journal of Medical Education Research 2012;11(1):93-95
The clinical internship is an important transitional period for humanistic spirit cultivation of the medical students.But in this period there are some problems exposed.For example,there is the lack of transitional link in management; the clinical instruction doctors lack educational consciousness or guidance ability,the medical students pay little attention to enhancing the individual humanistic spirit level and there is a gap between theory and practice of humanistic spirit for them.Strengthening training for students,attaching importance to training,selection and incentive of clinical instruction doctors and revising handbook of clinical internship will help to solve the problems.
9.The Cytologic Diagnosis and Analysis of Canceration of Breast Intraductal Papillomas
Xiaozhi WU ; Zhenhua ZHANG ; Guangping WU ; Xiuxia HUANG ; Peihang YAN
Journal of China Medical University 2001;30(2):141-142
Objective: The cytologic methods were used in the diagnosis of cancerous change of (intraductal papillomas,IP) and its significance was discussed. Methods: We studied the nipple discharge smear by using Wright-Gimsa staining. Meanwhile, infrared ray scanning B-ultrasound and X-rays were performed. Results: One hundred and twenty-eight patients were with IP, among them, 15 (11.7%)were confirmed as tumors by surgery and pathological examination. The cancerous change of cytomorphology was based on IP. The average age of patients with cancerous change was 48.1.The nipple discharge in patients with cancerous change was primarily bloody(66.7%). Conclusion: Introductal papillomas is carcerous. The possibility of canceration in persons with longer time of nipple discharge is larger than those with shorter time of nipple discharge. Women who are elder than 45 years old, with nipple discharge and post menopause, should be considered to have the possibility of cancerous change.
10.Pulmonary Diffusing Capacity and BALF Lymphocyte Phenotype in Sarcoidosis
Xiaolin HE ; Zhi LIU ; Lixia HUANG ; Zhenhua LI ; Runjiang YU
Journal of China Medical University 2001;30(2):130-132
Objective: Our aim was to study whether the cellular bronchoalveolar lavage fluid (BALF) profile was associated with the parameters of pulmonary function tests. Methods:Lung function tests and BAL were carried out in 18 untreated, non-smoking patients suffering from sarcoidosis and 18 normal subjects. Results:(1)Lung function tests were normal at rest in patients with sarcoidosis(P>0.05), the single breath carbon monoxide diffusing capacity decreased (P<0.05),and the small airway function decreased too (P<0.05).(2)The percentage of lymphocytes in BALF of sarcoidosis increased comparing with the normal subjects(P<0.01),and the ratio of CD+4 to CD+8 in BALF increased significantly in sarcoidosis(P <0.05), furthermore, the increase of both the percentage of lymphocytes and the ratio of CD+4 to CD+8 in BALF of sarcoidosis were well nagatively correlated with the decrease of the percentage of DLCO (r=-0.67, P<0.01 and r=-0.55, P<0.05, respectively), the decrease of mid-expiratory flow at 50% of vital capacity (FEF50%) was well correlated with the increase of the percentage of lymphocytes in BALF of sarcoidosis (r=-0.54, P<0.05). Conclusion:Pulmonary diffusing capacity(DLCO) was significently correlated with BALF lymphocyte phenotype,so was small airway function,and can act as the marker of activity of sarcoidosis.