1.Wireless real-time monitoring system for body temperature
Hongfu WANG ; Xuesheng LI ; Zhenhai SUN
Chinese Medical Equipment Journal 2004;0(07):-
The wireless real-time monitoring system for body temperature is based on electronic thermometry and wireless communication technology. It can measure and store the patient's body temperature during the desired time span, and can transmit the data to the computer terminal or the cell phone terminal through wireless transmission system.
2.Application of preoperative CT scanning in three- dimensional positioning of puncture route for percutaneous vertebroplasty
Shiqing SUN ; Zhenhai DI ; Zhongbao TAN
Journal of Interventional Radiology 2014;(6):532-535
Objective To discuss the feasibility of using three-dimensional simulation positioning of puncture route that is sketched according to the transversal and sagittal CT images to design percutaneous vertebroplasty (PVP) plan. Methods A total of 58 patients with 63 diseased vertebral bodies were enrolled in this study. Before PVP, the simulation puncture route was delineated according to the transversal and sagittal CT images, and the simulation puncture parameters were determined by using the software of PACS, in this way the three-dimensional simulation puncturing route was established , and the skin needle entry point as well as the puncture angle were calculated. Unilateral transpedicular approach was used when the simulation puncture route could meet the requirements of unilateral approach. Otherwise , bilateral transpedicular approach would be employed. Three months after PVP visual analogue score (VAS) was used to evaluate the degree of pain relief, and the result was compared with that determined before PVP. SPSS 13.0 software was used for statistical analysis. The estimating data were statistically analyzed with paired t-test and the results were expressed in the form of (x ± s). Results The measurement results showed that significant differences in the puncture angles and skin needle entry points existed between different vertebral bodies. Guided by the preoperatively determined simulation puncture route , PVP was successfully accomplished in all patients. The success rate of single puncturing was 100% (63 vertebral bodies in total). Among 63 vertebral bodies, unilateral transpedicular approach was adopted in 55 and the operation time was (28.5 ± 5.5) minutes, while bilateral transpedicular approach was carried out in 8 and the operation time was (37.5 ± 5.5) minutes. After PVP, complete pain relief was achieved in all patients. No serious complications occurred during the follow-up period. Conclusion Three-dimensional simulation positioning of puncture route that is sketched according to preoperative transversal and sagittal CT images is very useful in precisely determining the puncturing route before PVP, which is very helpful to increase the success rate of single puncture and to improve the procedural safety.
3.Netilmicin in the prevention of postoperative infection
Zhenhai YU ; Shujuan SUN ; Shuguang ZHANG
Chinese Journal of General Surgery 2000;0(12):-
Objective To determine the optimum administration modality of netilmicin (NTM) by comparing the blood concentration, bactericidal activity, clinical effect and adverse reactions at two different regimen. MethodSerum concentration was determined by TDx (Fluorescence Polarization Immunoassy Technology). Serum bactericidal activity (SBA) was determined by microdilution method. ResultAll trough concentrations were
4.Magnetorheological fluid shock absorber and its application prospect in the wounded transport vehicle
Xudong REN ; Jinggong SUN ; Zhenhai GAO ; Fu NIU
Chinese Medical Equipment Journal 2004;0(09):-
Magnetorheological fluid(MRF) is a sort of newly developed intelligent material.Because of the quick and adjustable magnetorheological effect of MRF,it is widely used in shock absorbers,clutches,polishing devices,hydraulic valves,etc.This paper mainly introduces magnetorheological fluid,magnetorheological effect,the work mode and characteristics of magnetorheological fluid shock absorbers as well as its application prospect in the wounded transport vehicle.
5.Development of a magnetorheological vibration isolator
Jinggong SUN ; Zhenhai GAO ; Fu NIU ; Deguang DUAN ; Xudong REN
Chinese Medical Equipment Journal 1989;0(02):-
Since vibration highly influences the performance of vehicles, the effective improvment of vibration isolation has a great significance for enhancing the economy, balance, stability and reliability of vehicles. Based on the variable viscosity properties of magnetorheological(MR) fluids with the variation of a external magnetic flied resulted from adjustable and controllable electric current, a magnetorheological vibration isolator is developed. Through experiment and application, it is proved that the magnetorheological vibration isolator can highly increase vibration isolation efficiency.
6.Herniography in the diagnosis of occult or recurrent inguinal indirect hernia
Peizhong SHANG ; Zhenhai ZHANG ; Yinchen SUN ; Jingzhang LIU ; Dengkai LIU
Chinese Journal of General Surgery 2001;0(08):-
ObjectiveTo improve the diagnosis of occult or recurrent inguinal indirect hernias. Methods 47 patients with obscure groin or incisional pain with normal physical examinations were undergone herniography. Results26 patients had hernias confirmed by herniography, including 22 indirect and 4 recurrent hernias. The symptoms disappeared after herniorrhaphy in the 26 patients. Eighteen of the other 21 patients with normal herniography were asymptomatic via other treatment 3 months after herniography. Conclusions Herniography is useful to diagnose the occult or recurrent inguinal indirect hernias in patients with inguinal region pain of unclear causes.
7.Short and Long Term Efficacy and Safety of Pancreaticoduodenectomy for Pancreatic Head Carcinoma and Periampullary Carcinoma
Shengjie DONG ; Xinhe HUO ; Zefeng ZHANG ; Zhenhai SUN ; Yuhong LUO
Progress in Modern Biomedicine 2017;17(23):4537-4540
Objective:To investigate the recent and long-term efficacy and safety of pancreaticoduodenectomy for pancreatic head carcinoma and periampullary carcinoma.Methods:82 cases of pancreatic cancer combined with periampullary carcinoma patients admit ted in our hospital from August 2009 to June 2013 were selected and randomly divided into the control group and the observation group With 41 patients in each group.The control group received palliative surgical treatment,while the observation group underwent pancreatoduodenectomy.The operation time,hospitalization time,intraoperative bleeding volume and the incidence of complications,1,2,3-year survival rate and the recurrence rate at 1 year after operation and tumor eradication rate were compared between twp groups.Results:The amount of bleeding,operation time of observation group were significantly higher than those of the control group(P<0.01),no signif icant difference was found in the hospitalization time between the two groups(P>0.05);the incidence of complications in the observation group (41.46%) was significantly higher than the control group (22.96%)(P=0.03);the 2-year and 3-year survival rate of observation group were significantly higher than those of the control group (P<0.05),the recurrence rate at 1 year after operation of observation group was significantly lower than that of the control group (P=0.04),the tumor eradication rate was significantly higher in the observation group than that of the control group (P=0.04).Conclusion:Though pancreaticoduodenectomy could prolong the operation time,increase the risk of bleeding and complications for pancreatic head carcinoma and periampullary carcinoma,but it could effectively reduce the possibility of recurrence after operation,significantly improve the long-term survival rate.
8.Modulation of Caspase expression by up-regulating histone acetylizad level with VPA
Xia ZHAO ; Changwen SHI ; Jingjie SUN ; Lili CAO ; Jie LI ; Zhenhai YU
Chinese Journal of Immunology 1985;0(03):-
Objective:To investigate modulation of a specific HDAC inhibitor,Valproate acid sodium(VPA),on expression of Caspase3,Caspase8,Caspase9 by inhiting HDAC,as well as apoptosis rate of cancer cells treated with VPA and the specific inhibitors of Caspase3,Caspase8,Caspase9.Methods:Heptocellular carcinoma cells-HepG2,gastric carcinoma cells-BGC-823 and breast cancer cells-MCF-7 were cultured with 0.75-4.0 mmol/L of VPA for 48 hrs in vivo,apoptosis was analyzed by flow cytometry with Annexin V/PI assay.The activities and protein expressions of Caspase3,Caspase8,Caspase9 were detected by spectrophotometry and indirect immunofluorescence technique.Results:Contrary to control groups,VPA at concentrations between 0.75 and 4.0 mmol/L induced a significant apoptosis in HepG2,BGC-823,MCF-7 cells(P0.05).The apoptosis rates of cancer cells treated with VPA and specific inhibitors of Caspase3,Caspase9 together was lower than in the groups with VPA treatment singlely(P
9.Abiological protective respirator with equal protection level of the half face mask
Yuee ZHAO ; Jianchun LU ; Zhanbo WEN ; Jianjun ZHAO ; Jinsong LI ; Zhenhai SUN ; Taoxing SHI
Chinese Medical Equipment Journal 2003;0(12):-
Medium filtering efficiency and loading capacity have been evaluated using staphylococcus aureus aerosol,0.75?m NaCl aerosol and Ecoli.F2 phage aerosol,and the face fit factor of actual wearing has been tested under eight predefined activities.The results have shown that the filtration efficiencies of respirator for the three kinds of tested aerosol were above 99 percent,the breathing resistance was less than 250 Pa,and while the load reached 150mg,the breathing resistance of the respirator was still below standards.The fit factors of most of the objects were over the detection capacity of the international standard test set.Our mask offers the best biological protection quality of all the protection equipments in international market.The new biological protective respirator comes to the equal protection result of the half face mask.It can be stored in a flat surface construction form,while be used in the cavity construction style.It is convenient for the troops to be equipped and applied for its smaller physical volume and lighter weight.
10.Study of regulating histone acetylizad level with VPA on the proliferation of breast cancer cells
Changwen SHI ; Xia ZHAO ; Jingjie SUN ; Lili CAO ; Zhenhai YU ; He GU
Journal of Chinese Physician 2008;10(7):907-910
Objective To investigate the effect and the mechanism of up-regulating histone acetylizad level with a selective inhibitor of HDACs-Valproate acid sodium (VPA) on breast cancer cell proliferation. Methods MCF-7 cells were cultured with 0.75-4.0 mmol/L valproic acid (VPA) for 24, 48, 72, 96 hours in vitro, the inhibiting rate was tested by MTT assay. Cell cycle was analyzed by flow eytome- try with PI assay, and the protein and mRNA expressions of Cyelin A, Cyclin DI, Cyclin E, P21Waf/cipl of MCF-7 cells after 1.5, 3.0 mmol/ L VPA treated were analyzed by indirect immunofluorescence technique and RT-PCR respectively. Results After cultured with 0.75 -4.0 mmol/L valproic acid (VPA) for 24, 48, 72, 96 hours, the inhibiting rate of experimental groups increased significantly(P<0.01) and a dose and acting time dependent manner was found. As to cell cycle, the percentages of GI, S, M phrase in control groups remained the same. Contrary to control groups, 0. 75 -4.0 mmo]/L VPA induced a significant arrest in G1 phrase ( P<0.01), and a total of 55.4% -82.8% G1 phrase ratio were found. P21Waf/cipl was up-regulated both at the mRNA and protein level while Cyclin D1 was down-regulated ( P<0.001). Conversely, neither mRNA nor protein expression of Cyclin A, Cyclin E showed difference ( P>0.05). Conclusions Up- regulating histone acetylizad level can inhibit breast cancer cell proliferation, induce cell cycle arrest in G1 phrase. VPA, as a I class of histone deaeetylase inhibitor, can be used as an option in the treatment of breast cancer. The mechanism may include up-regulating P21Waf/cipl mRNA and protein expression and down-regulating Cyclin D1 mRNA and protein expression.