The fluid status variate sharply in patients after operation. Appropriate fluid therapy is essential to reduce perioperative complications, shorten hospitalization days and improve prognosis of postoperative patients. In this article, we reviewed the relevant issues about fluid therapy strategy for postoperative patients such as the variation of body fluid in patients after operation, the assessment of fluid status, the establishment of the goal of fluid therapy and the selection of strategy or fluid for fluid therapy in patients after operation.

OBJECTIVE: To find out the critical influential factors of measurement in the determination of Roxithromycin dispersible tablets. METHODS: Mathematic model of HPLC was established to analyze the effects of many uncertain factors on measurement results. Combined standard uncertainty and expanded standard uncertainty were calculated. RESULTS: The expanded uncertainty was 1.6% and the results of determination could be expressed as (96.8?1.6)%. CONCLUSION: The established analytical method is applicable to the uncertainty analysis in the content determination of Roxithromycin dispersible tablets by HPLC.

Objective To study the feasibility of minimally invasive procedure for the management of dumbbel tumors of the cervical vertebral canal. Methods Fourteen cases of dumbbel tumors of the cervical vertebral canal were treated by the approch of semi-laminectomy. Results Twelve cases underwent total resections, one case underwent subtotal resection, another case underwent great part of resection. The vertebral artery was preserved well during the operation. Nine out of fourteen cases had followed up for 6～18 months. Neurological function was improvement in all cases. No recurrence or instability of spine was found. Conclusions The approch of semi-laminectomy has the advantages of minimal invasion, less bleeding, and no influence on stability of spine. It is a good choice for dumbbel tumors of the cervical vertebral canal

Objective To isolate water-soluble neutral polysaccharides(NTPS) and acidic polysaccharides(ATPS) from tea,investigate their hypoglycemic effects,and elucidate the relationship between structure and activity.Methods Weak base macroporous anion-exchange resin D315 was used to isolate two kinds of tea polysaccharides NTPS and ATPS based on electric charge of tea polysaccharides.Their monosaccharide compositions were analyzed by gas chromatography and ion chromatography.NTPS and ATPS were further isolated by DEAESepharose FF.Molecular weights of the main fractions were analyzed by HPGPC.The model of diabetic mellitus was established by ip alloxan in mice.The blood samples were collected with tail vein puncture to determine blood glucose.The hypoglycemic activity between neutral and acidic polysaccharides was compared after ig tea polysaccharides for 12 d successively.Results Both NTPS and ATPS were(heteropolysaccharides.) NTPS was mainly composed of neutral polysaccharide and its main monopolysaccharide was D-galactose.NTPS contained 6.82% galacturonic acid.Whereas,ATPS was mainly composed of acidic polysaccharide and contained 33.02% D-galactose,whose neutral polysaccharide was mostly(L-)rhamnose,D-arabinose and D-galactose. The molecular weights of both two kinds of tea polysaccharides were less than 3?10~4.Continuous ig administration of NTPS and ATPS [200 and 400 mg/(kg?d)] for 12 d was found to depress glucose increases in alloxan-dependent diabetic model mice.Conclusion Two different structures of tea polysaccharides NTPS and ATPS are isolated by anion-exchange resin D315 firstly.Both tea polysaccharides show good hypoglycemic effect.

Objective To investigate the risk factors of primary gout.Methods 420 patients with primary gout were analyzed.Results Among the 420 patients,male to female ratio was 21∶1.Average onset age of female was significantly higher than that of the male,whereas,the mean disease duration was significantly shorter in female than that in male.The mean disease duration of patient with positive familial history was significantly shorter than that with negative ones.38% patients had an alcohol abuse history,and 54 percent patients had had high purin food intake.Mean weight of body was (74.7?9.9)kg,and average body mass index(BMI) was (27.3?2.6).Events of inducing acute attack included engorgement,tire,infection,operation and trauma.Conclusion Risk factors of primary gout include age,sex,inherity,food habit,hyperlipemia,renal function failure.Engorgement,tire,infection,operation,trauma and use of diuretics could induce gout acute attack.It should be taken importance to that the onset age shows a young tendency.

Objective : To investigate the mediating effect of negative emotions on visual impairment and resilience among middle-aged and elderly populations, so as to provide insights into improving psychological health among middle-aged and elderly populations. Methods: Demographic information, visual impairment, negative emotions and resilience in the residents at ages of 45 years and older were collected through the database of the Yushu Physical and Mental Health Survey carried out by Institute of Psychology of Chinese Academy of Sciences. Structural equation model was used to analyze the effects of visual impairment and resilience and the mediating role of negative emotions. Results: Totally 2 997 middle-aged and elderly populations were enrolled, with the median age of 50.00 (interquartile range, 47.00) years. There were 1 320 males (44.04%) and 1 677 females (55.96%), 1 627 illiterate persons (54.29%), and 2 780 married persons (92.76%). The scores of visual impairment, negative emotions and resilience were (6.79±2.59), (6.35±3.05) and (33.38±10.41) points, respectively. The results of structural equation model analysis showed that after adjusting for age, gender, educational level and marital status, visual impairment had a direct negative positive effect on resilience, with a direct effect value of -0.157 (95%CI: -0.177 to -0.137), and visual impairment could also negatively affect residence through negative emotions, with a mediating effect value of -0.112 (95%CI: -0.126 to -0.104), and the mediating effect contributed 41.64% to the total effect. Conclusion visual impairment could reduce residence directly or indirectly through the mediating effect of negative emotions among middle-aged and elderly populations.

Acupuncture Therapy ; Adult ; Female ; Humans ; Warts ; therapy

Acupuncture Points ; Acupuncture Therapy ; Adult ; Chronic Disease ; therapy ; Eczema ; therapy ; Humans ; Male

A series of 5-amino-2-( benzylthio ) thiazole-4-carboxamide derivatives were designed and synthesized to discover novel compounds with anti-tumor activity. Compounds DDO-5401-DDO-5416 were synthesized using 2-amino-2-cyanoacetamide as the start material. The structures of the synthesized compounds were confirmed by IR, 1 H NMR and ESI-MS. The in vitro anti-tumor activities of the synthesized compounds were determined by MTT assay in HCT116 , HepG2 , A549 , MDA-MB-231 and MCF-7 cell lines. Target compounds showed good anti-tumor activity especially in A549 cell line. SAR study showed that electron donating groups were more favorable than electron absorption ones. Compound DDO-5413 exhibited noteworthy activity in MDA-MB-231 and MCF-7 cell lines with IC50 value lower than the positive reference dasatinib. It suggested that DDO-5413 might be the candidate for further investigation.

0.05).[Conclusion]Periarticular drug injection during TKA and intra-articular drug injection after operation can relieve pain early after TKA,improve the range of motion of the knee and rehabilitation,no further side effect has been noted.