1.Research Status of Artificial Joint Materials
International Journal of Biomedical Engineering 2009;32(4):247-250
With the improvement of living standard, the requirement of artificial joint material is ever increasing. The development of meted artificial joint, high polymer artificial joint and ceramic-made artificial joint, which are widely used in joint replacement, are introduced. Advantages and disadvantages of these materials are discussed, as well as the required improvement to these three materials. Development on metal-to-metal hip resurfacing arthroplasty and its clinical application is introduced. Now that no material with good biocompatibility, good biomechanical compatibility, good biological aasociativity and satisfied life-span has yet been found, compound material artificial joint may be the focus of the research in future.
2.Research on using risk of medical equipment based on root cause analysis
China Medical Equipment 2014;(1):76-79
Objective: To find the reason of risk on medical equipment. Methods: Based on RCA, to adopt the event classification to evaluate the X-ray equipment, high-frequency electro tome, electro-cardiac monitor, infusion pump, ventilator, defibrillators and infant incubator, discuss the root cause of medical risk. Results:To deduce the medical equipment risk by PM and quality control. Conclusion:With the analysis of quality control, the application of RCA is gradually explained in management of medical equipment.
3.Application of AHP in medical equipment risk evaluation
Zhengying QIAN ; Wei JIN ; Jun YANG
China Medical Equipment 2015;(9):59-61,62
Objective:Using analytic hierarchy process(AHP)method to construct the risk evaluation of medical equipment.Methods: Combine the professors’ suggestion, data of maintenance and quality control to several medical equipments in different hospitals. Screen six kinds of medical equipment, including infant incubator, high-frequency electrotome, defibrillator, ECG monitor, ventilator and infusion pumps.Results: Ventilator has highest risk and need to be concentrated.Conclusion: The results can guide quality control, patrol, and maintenance.
4.Development of a real-time monitoring platform for medical equipments using multi-mode data acquisition
Zhengying QIAN ; Wei JIN ; Jun YANG ; Chongde SHEN
Chinese Journal of Hospital Administration 2017;33(8):608-610
The authors described the architecture of a real-time platform designed to monitor medical equipments.Three types of data collectors were employed to collect information into the background servers for real-time analysis and presentation.Such a platform can effectively enable the hospital to manage its medical equipments, for their positioning, assets management and risk control.
5.Construction and finite element analysis of normal and osteoporotic hip models
Sutong GUO ; Dehong FENG ; Yu GUO ; Ling WANG ; Yujian DING ; Yi LIU ; Zhengying QIAN ; Mingyang LI
Chinese Journal of Tissue Engineering Research 2024;28(9):1342-1346
BACKGROUND:Bone mineral density is the clinical gold standard for determining bone strength,but bone mineral density is less sensitive to changes in bone mass,with large changes in bone mineral density only occurring when bone mass is significantly reduced,so bone mineral density has limited ability to predict changes in bone strength and fracture risk. OBJECTIVE:A model of the normal and osteoporotic hip joint was developed to analyze the stresses and deformation in the hip of normal and osteoporotic patients under single-leg standing conditions. METHODS:A healthy adult female volunteer at the age of 36 years was selected as the study subject.The CT data of the hip joint of this volunteer were obtained and saved in DICOM format.The hip joint model was reconstructed in three dimensions,and the material properties were assigned by the gray value assignment method to obtain the normal and osteoporotic hip joint models according to the empirical formula.The same boundary conditions and loads were set to simulate the stresses and deformation in the normal and osteoporotic hip joints in the single-leg standing position. RESULTS AND CONCLUSION:(1)In the finite element model of the normal and osteoporotic hip,the stress distribution was more concentrated in the medial region of the femoral neck.(2)In the hip bone,the stress distribution was mainly concentrated in the upper part of the acetabulum.(3)The stress peaks in the medial femoral neck and upper acetabulum were larger in the normal hip model than in the osteoporotic hip model,probably due to the reduced bone strength of the osteoporotic bone.(4)The peak Von Mises of both normal and osteoporotic hip models were concentrated on the medial femoral neck,and the peak Von Mises of the hip bone was smaller,indicating that the overall effect of osteoporosis on hip bone stresses was relatively small.(5)In terms of deformation in the single-leg standing position,the maximum deformation in the normal hip model was located at the acetabulum and femoral head,and the maximum deformation was located at the upper part of the greater trochanter of the femur.(6)It is suggested that the finite element analysis method to model the values of parameters related to bone tissue in osteoporosis may improve clinical prediction of bone strength changes and fracture risk.It is explained from the biomechanical view that the intertrochanteric femur and femoral neck are good sites for osteoporotic hip fractures.
6.Digital design and 3D-printed customized flanged cups in hip revision with severe acetabular bone defects
Yujian DING ; Dehong FENG ; Ling WANG ; Yu GUO ; Yi LIU ; Yiyi ZHOU ; Sutong GUO ; Zhengying QIAN ; Kuixue XU ; Zhaofeng ZHANG
Chinese Journal of Orthopaedics 2023;43(2):97-103
Objective:To investigate the effect of 3D-printed customized flanged cup in hip revision with severe acetabular bone defects.Methods:Since February 2017, 10 cases of 3D-printed customized flanged cups were used in hip revision with severe acetabular bone defects, including 2 cases of Paprosky type IIIA and 8 cases of Paprosky type IIIB. There were 5 males and 5 females, mean age 73.6±8.1 yrs (range, 62-87 yrs), 5 left and 5 right cases. The preoperative thin-layer CT scan was preformed to reverse reconstruct digital pelvis. Five cases of one-piece flanged cups and 5 cases of decomposed flanged cups, including 3 cases of composite one-piece cups were designed by computer. The surgery was performed strictly according to the plan.Postoperative follow-up was performed to evaluate the Harris score. Operation time,intraoperative bleeding and other complications such as vascular and nerve injury, postoperative infection, and dislocation were counted. Pelvic X-ray was used to assess the height and horizontal position of the center of rotation and the stability of the prosthesis.Results:The surgical procedure was successful, with an average operative time of 147.9±48.3 min (range, 96-212 min) and an average intraoperative bleeding of 730.4±262.6 ml (range, 500-1 300 ml). The mean time of final follow-up was 40.8±18.7 months (range, 16-70 months) after surgery. At the last follow-up, the average Harris score was 83.80±6.73, with 4 cases excellent, 5 cases good, and 1 case fair. The excellent and good rate was 90%. The last Harris score was significantly higher than that before operation 28.60±8.40 ( t=16.84, P<0.001). The height of affected hip joint rotation center decreased from 46.24±7.74 mm before operation to 15.54±2.54 mm after operation with significant difference ( t=14.61, P<0.001). It was slightly higher than the opposite side (13.81±1.48 mm), which had no significant difference ( t=1.83, P=0.100). The horizontal distance of affected hip joint rotation center increased from 33.79±5.27 mm before operation to 40.53±4.50 mm after operation with significant difference ( t=3.62, P=0.006). It had no significant difference ( t=1.28, P=0.232) compared with the opposite side (38.54±3.46 mm). All incisions were healed in one stage without infection, vascular or nerve injury. During the following-up, all prostheses were in satisfied position without loosening, dislocation or screw breaks. Conclusion:Digitally assisted 3D-printed flanged cups can be used in hip revision with severe acetabular bone defect. It can not only improve hip joint function, but also restore the acetabular rotation center and the prosthesis stability, which can achieve good early and mid-term effect.
7.Effects of esketamine for multimodal analgesia on opioid consumption and gastric motility in mechanically ventilated non-surgical ICU patients
Yi LONG ; Qian LIU ; Rui LI ; Guixin WU ; Aiting HE ; Zhengying JIANG
China Pharmacy 2024;35(4):468-471
OBJECTIVE To investigate the effects of esketamine for multimodal analgesia on opioid consumption and gastric motility in mechanically ventilated non-surgical intensive care unit (ICU) patients. METHODS Forty cases of mechanically ventilated non-surgical patients in the ICU of our hospital from February 1st, 2023 to July 31st, 2023 were selected and randomly divided into control group and esketamine (S-K) group using grouping method with opaque envelopes, with 20 cases in each group. Control group was given sufentanil, and S-K group was infused with Esketamine hydrochloride injection at a constant rate of 0.2 mg/(kg·h)+ sufentanil. The treatment period length, analgesic compliance rate, sedation level, analgesic and sedative consumption, and gastric motility indexes were compared between the two groups. RESULTS There was no statistically significant difference in the treatment period length, analgesic compliance rate, sedation level, or the consumption of propofol and midazolam between the two groups (P>0.05). The consumption of sufentanil in the S-K group was significantly less than control group (P< 0.05). Compared with 1 h after randomization, the antral contraction frequency, antral contraction amplitude and antral motility index of patients in the S-K group were significantly higher at 72 h after randomization and were significantly higher than control group (P<0.05). CONCLUSIONS Esketamine may reduce opioid consumption and improve gastric motility in mechanically ventilated non-surgical ICU patients while ensuring a level of analgesic sedation.