Objective To investigate the effect of group psychotherapy on depression in the elderly. Methods A total of 82 elderly patients with depressive disorder were enrolled and assigned to the control group ( n = 40 ) and therapy group ( n = 42 ). The control group obtained general psychological guide and drug therapy, while the therapy group received group psychotherapy and anti-depressants for 4 weeks. One week before and after the intervention, Hamilton depression scale (HAMD) and synthetic life quality scale were used to estimate the functions of the participants. Results At 4 weeks, total score of HAMD of the therapy group was significantly lower than that of the control group (P＜0. 01 ). Synthetic life quality score showed that body, mental and social functions and life quality of the therapy group were significantly higher than the control group. Conclusion Group psychotherapy could be an effective and acceptable treatment for depression in the elderly.

Objective To investigate the effects of multifactor intervention on the rehabilitation outcomes of stroke patients. Methods A total of 85 stroke patients were randomly assigned to the treatment group (receiving intervention plan assessment before undergoing multifactor interventions) and the control group ( receiving conventional rehabilitation). Results The effectiveness of the treatment or control group was 95.3% and 83. 3%, respectively. After the intervention, the patients' potential and alternative risk factors were significantly decreased,although clinical efficacy was largely increased (P ＜0. 01 ). Conelusion Multifactor intervention on elderly stroke patients may be an effective treatment method to control the risk factors and recurrence of stroke.

Objective To observe the efficacy of continuous renal replacement therapy (CRRT) treatment in multiple organ dysfunction syndrome (MODS),and explore its application value.Methods Forty-six cases of MODS were treated with CRRT.Blood gas analysis,toxin removal,electrolyte and APACHE Ⅱ score was observed before and after treatment.Results The APACHE Ⅱ score in the beginning of treatment was (20.8 ±4.4) scores,31 cases had clinical cure,and APACHE Ⅱ score was (13.6 ±4.9)scores,15 cases died.In patients of survival,blood pressure,blood gas analysis,electrolytes,toxin removal improved gradually,and the difference had statistical significance before and after treatment.In 8 cases withshock before treatment who need drugs to maintain blood pressure,after treatment 6 cases withdrew drugs gradually.In the course of treatment,heart function was stable in patients who had heart failure.Four cases had pulmonary infection-induced MODS.In the process of the treatment internal environment was stable,and urine after treatment improved in different degrees.Two cases died of drug-resistant pathogens ultimately.Conclusions CRRT is an effective method in the treatment of MODS patients.CRRT can effectively clear the metabolites and inflammatory mediators,and rebuild the immune homeostasis of the body.

Objective To investigate the quality of life (QOL) of hemodialysis patients and its influencing factors.Methods One hundred and twenty-five patients who underwent maintenance hemodialysis treatment for more than 3 months were selected,and their age,gender,combined disease and dialysis status were recorded.Hemoglobin,albumin and urea clearance index (Kt/V) were tested.Charlson complications index,Karnofsky activity index,Hamilton Depression Scale and MOS 36-item short health survey questionnaire were used to assess complication,activity,and psychological situation of the patients.Results Of the 125 patients,there were 7 (5.6％) grade 1 patients (could not take care of themselves),43 (34.4％) grade 2 patients (could only take care of themselves),47 (37.6％) grade 3 patients,and 13 (10.4％) grade 4 patients.A significant relationship between rehabilitation status and age was found.Young patients were better than older patients (x2 =5.864,P ＜ 0.05).The majority of grade 1 patients were older and had been diagnosed with diabetes,and their Karnofsky activity index,Charlson complications index and Hamilton Depression Scale index were lower than Grade 2-4 patients(t values were 5.263,7.866,6.215 and 5.474,respectively; all P ＜ 0.05).The QOL of the patients were related with age,diabetes,dialysis,serum albumin level,activity index,index of Charlson complications and Hamilton depression (r =-0.618,-0.512,0.593,0.369,0.801,-0.696 and-0.516,respectively).Conclusions The QOL of maintenance hemodialysis patients may be related with physical,psychological,and many other factors.It should be needed to strengthen health care and emotional support to the patients.

Cardiovascular disease caused by atherosclerosis has been the world′s primary cause of death. Studies have shown that early intervention in preclinical stage of atherosclerosis among children can reverse the disease and ultimately reduce the morbidity of atherosclerosis related diseases after they grow up,which is crucial to reduce and eliminate the harm of atherosclerosis.Now,the risk factors and detection methods of children′s preclinical atherosclero-sis were reviewed.

Objective To investigate the correlative factors for osteoporosis among senile patients with multiple cardiovascular diseases and type 2 diabetes mellitus.Methods 206 patients were divided into osteoporosis (OP) group and non-osteoporosis (non-OP) group according to the diagnosis standards of osteoporosis.The general data were recorded.Clinical history of all kinds of cardiovascular diseases and type 2 diabetes mellitus were detected.Serum levels of hemoglobin (Hb),glucose (Glu),glucosylated hemoglobin (HbA1c),alkaline phosphatase (ALP),total serum protein (TP),albumin (ALB),BUN,creatinine (Cr),calcium (Ca),phosphonium (P),total cholesterol (TC),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C) were detected.Dual-energy Xray absorptiometry was used to detect the bone mineral density (BMD) of bilateral femoral neck and lumbar spine.The related factors of BMD were analyzed.Results The morbidity of osteoporosis was much higher in elderly females than in elderly males (58.7％ vs.38.6％).The osteoporosis patients were older than non-osteoporosis patients in both males and females,although there was no significant difference.The body mass index (BMI) of both gender was much lower in osteoporosis group than in non-osteoporosis group (P＜0.05).In male patients,BMD was positively correlated with BMI significantly (P＜0.01).In female patients,TC and LDL C were higher in OP group than in non-OP group (P＜0.05).In female patients,BMD was positively correlated with BMI,and negatively correlated with TC and LDL-C.Logistic regression analysis showed that the lower BMI was an independent risk factor for osteoporosis in male patients; BMI and TC were independent risk factors for osteoporosis in female patients.Conclusions In both male and female,senile patients with lower BMI,multiple cardiovascular diseases and type 2 diabetes mellitus have higher risks for osteoporosis.In senile female patients,TC may be correlated with BMD.TC should be reduced to decrease the risks of cardiovascular diseases and osteoporosisin senile females.

Objective To identify the types of Taenia saginata isolated from Dali of Yunnan Province, and from Duyun and Congjiang of Guizhou Province.\ Methods\ Genomic DNA was isolated, and the mitochondrial cytochrome C oxidase subunitⅠ(mtCOⅠ) genes were amplified by polymerase chain reaction(PCR) and analyzed by PHYLIP software package.\ Results \ The mtCOⅠgene sequences of Lanping sample were identical to that of T\^saginata asiatica known in Taiwan, and the samples obtained from Dali and Duyun showed the same mtCOⅠgene sequences, while the sample from Congjiang had the same mtCOⅠgene sequences as T\^saginata . The homology between these two groups of gene sequences was 97\^44%, while the homology of amino acid sequences reached to 99\^16%. The constructed phylogenetic tree revealed that the relationship between T\^saginata asiatica and T\^saginata is closer, both are distant relative to T\^solium and other species of cestodes.\ Conclusion \ The Taenia prevalent in Lanping, Dali and Duyun is identified as T\^saginata asiatica , while that isolated in Congjiang is the typical T\^saginata.

OBJECTIVE To investigate the antibiotic resistance status in coagulase negative staphylococcus (CNS) strains and provide the scientific evidence for the reasonable use of antibiotics. METHODS The drug resistance of 251 strains of CNS was ananlyzed. RESULTS The detection rate of methicillin-susceptible coagulase-negative Staphylococcus(MSCNS) was 12.75% (32/251), while that of methicillin-resistant coagulase-negative Staphylococcus (MRCNS) was 87.25%. The drug-resistance rate of MRCNS was higher than that of MSCNS. Vancomycin resistant and intermediate strains had not been detected. CONCLUSIONS Laboratory should monitor the drug resistance well and update in time to offer the evidence for the reasonable use age of the antibiotics.

Objective: To evaluate the effectiveness that gelatin lines the injured vasuclar wall to prevent from restenosis.Methods: The animal model of restenosis was established by balloon dilation in femoral artery,and 30% gelatin was lined on injured vascular wall in experimental group.The samples were collected at the 2nd week and 4th week after operation.The neointimal area(NEA),neointimal area/media area(NEA/MA)and cell apoptosis were observed by image analysis system and TUNEL technique. Results: The intima of the control group was thicker than that of the experimental group,and more cells appeared in the control group.Compared with the control group,the NEA was reduced significantly in the experimental group at the 2nd and 4th week (0.67?0.25cm 2 vs 1.02?0.41cm 2,and 1.18?0.36cm 2 vs 1.46?0.15cm 2).The NEA/MA ratio in the experimental group was lower than the control group at the 2nd and 4th week(0.35?0.05% vs 0.54?0.14%,and 0.62?0.25% vs 0.75?0.10%).The apoptosis rate of vascular smooth muscle in the experimental group was higher than the control group at the 2nd and 4th week(18.2?5.8% vs 13.6?2.4%,and 15.1?2.1% vs 13.0?1.5%).These diffences were all significant (P

Objective:To investigate the levels of parathyroid hormo ne -related protein(PTHrP) in mandibular condylar cartilage during mandible forwar d positioning in different seasons. Methods:64 SD rats were rand omly divided into four groups according to seasons. Orthodontic appliance was us ed in 32 rats for 12 hours each day in daytime for mandibular protrusion. 8 rats were sacrificed at each season time point.Condyle samples were processed for PT HrP detection by a two-site immunoradiometric assay (IRMA) method.Another 32 ra ts without treatment were used as the controls.Macroscopic and microscopic appro ach were applied to analyze the results. Results:The level of P THrP in mandibular condylar cartilage(MCC) in the group of orthodontic treatmen t was higher than that in the control group(P