1.Investigation of Rehabilitation Professionals in Hospitals above Grade 2A in Jiangsu
Zhengquan CHEN ; Jiqing HU ; Pengpeng ZHU ; Yong JIAO
Chinese Journal of Rehabilitation Theory and Practice 2015;21(4):494-496
Objective To investigate the number, structure and demand of rehabilitation professionals hospitals above grade 2A in Jiangsu. Methods 176 hospitals above grade 2A in Jiangsu were investigated with questionnaire in the topics of general condition of department of rehabilitation medicine, structure of rehabilitation professionals and demand of rehabilitation professional. Results 64% of the hospitals has established department of rehabilitation. Rehabilitation professionals, such as the rehabilitation physician, therapists, nurses and engineer were in a total of 1657, and 231 professionals were needed further. Conclusion There are problems of lack of the department of rehabilitation medicine and rehabilitation professional, with the imbalance structure of professional in hospitals above grade 2A in Jiangsu.
2.Comparison of the effects of two different methods of craniotomy in the treatment of elderly patients with hypertensive striatocapsular hemorrhage
Yonghua CUI ; Yongben XIA ; Zhengquan YU ; Zhangming WANG ; Xiaowen ZHU
Chinese Journal of Primary Medicine and Pharmacy 2018;25(2):137-140
Objective To compare the clinical effect of the small bone flap craniotomy and traditional craniotomy in the treatment of elderly patients with hypertensive striatocapsular hemorrhage .Methods According to the digital table ,80 patients with hypertensive striatocapsular hemorrhage were randomly divided into control group and treatment group ,40 cases in each group .The treatment group was treated with small bone flap craniotomy ,and the control group was treated with traditional craniotomy .The operative incision length ,intraoperative blood loss ,operation time,hematoma clearance rate,rebleeding rate,GCS score,postoperative pulmonary infection rate and GOS score in the 1 month after treatment were compared between the two groups .Results The operative incision length , intraoperative blood loss, operative time, GCS score after 1 week, pulmonary infection of the treatment group were (7.0 ±1.5)cm,(100 ±35)mL,(1.5 ±0.6)h,(12.5 ±1.4),25.0%,respectively,which of the control group were (18.0 ±4.5)cm,(500 ±85) mL,(2.2 ±0.8) h,(10.5 ±1.1),47.5%,respectively,the differences between the two groups were statistically significant (t=303.791,P=0.000;t=244.467,P=0.000;t=24.366,P=0.003;t=3.294,P=0.031;χ2 =4.381,P=0.036).The hematoma clearance rate,rebleeding rate of the treatment group were 90.0%,7.5%,respectively,which of the control group were 85.0%,10.0%,respectively,there were no statistically significant differences between the two groups (χ2 =0.457,P=0.499;χ2 =0.157,P=1.692).The prognosis of the patients in the treatment group was significantly better than those in the control group (Z=-2.022,P=0.043). Conclusion The small bone flap craniotomy in the treatment of hypertensive striatocapsular hemorrhage has the advantages of less trauma , shorter operative time , less intraoperative bleeding , high hematoma clearance rate , low rebleeding rate,low complication rate and good prognosis .
3.Treatment of hypertensive basal ganglia cerebral hemorrhage with different surgical approaches
Yonghua CUI ; Yongben XIA ; Zhengquan YU ; Zhangming WANG ; Xiaowen ZHU ; Cheng ZHANG
Chinese Journal of General Practitioners 2018;17(2):143-145
According to the locations of main hematomas,60 patients with hypertensive basal ganglia hemorrhage were surgically treated through different approaches from June 2014 to September 2017.Thirty six cases with anterior hematoma near the Sylvian point were treated through transsylvian-transinsular approach,24 cases with the posterior hematoma far from the Sylvian point were treated through translower-rolandic-point (transLRP) transinsular approach (n =11) or transsuperior-temporal-sulcus (transSTS) transinsular approach (n =13),respectively.All patients were followed up for at least 6 months and evaluated by Glasgow Outcome Scale.Fourteen patients showed good recovery,25 patients showed moderate disability,18 patients showed severe disability,one patients showed vegetative survival and two patients died.
4.The analysis of AQP4 expression level in different pathological of the glioma
Kezi DUSHANBIEKE ; Zhengquan ZHU ; Liang LIU ; Zhe SUN ; Haicheng XIA
Chinese Journal of Experimental and Clinical Virology 2014;28(1):26-27
Objective Explore the difference of water channel protein 4 (AQP4) 's expression level in different grade glioma tissues.Methods select 57 cases of paraffin embedding glioma tissues and 10 cases of normal brain tissue in our hospital from 2008 to 2012,use immunohistochemical method to test the level of AQP4 and do statistical tests.Results The AQP4 expression level in high grade glioma tumor tissues is higher than in the low grade glioma and normal brain tissue (P < 0.05),and there is no statistical significance about the difference AQP4 expression levels between low grade glioma tumor tissue and normal brain tissue (P > 0.05).Conclusions AQP4 expression level in glioma is closely related to the tumor pathological level.
5.Studies of the effects on serum VEGF level in patients with glioma
Zhengquan ZHU ; Dushanbieke.Kezi ; Haicheng XIA ; Liang LIU ; Changjiu TANG ; Damin ZHANG
Chinese Journal of Experimental and Clinical Virology 2015;29(1):56-58
Objective To investigate the influence of the serum vascular endothelial growth factor (VEGF) in the glioma patients by the malignant degress.Methods Quantitative analysis the serum VEGF levels with the double antibody sandwich assay (ELISA) for 35 cases of glioma patients and 10 cases of healthy human and analyze the correlation of them.Results Mean serum VEGF expression in glioma patients was 120.71 ±45.99 pg/ml,normal value of the healthy people was 63.70 ± 6.50,the difference was statistically significant (P <0.05); serum VEGF expression was 156.43 ± 14.90 pg/ml in high-grade glioma patients (Ⅲ-Ⅳ grade) and 67.14 ± 6.12 pg/ml in low-grade glioma patients (Ⅰ-Ⅱ grade),the difference was statistically significant (P < 0.05) ; there' s no different from low-grade glioma patients (Ⅰ-Ⅱ grade) and nomal(P > 0.05).Conclusion The serum VEGF levels in the glioma patients was influence by the malignant degress.