1.Study on Countermeasures to Managing Shuangjiantiao(Double Duties) Cadres in TCM Colleges
Wenxiu HUANG ; Jianliang ZHU ; Zhengping YE
Journal of Zhejiang Chinese Medical University 2014;(7):906-908
Objective To analyse the problems and reasons in the management of Shuangjiantiao cadres in TCM col eges, put forward scientific management countermeasures and suggestion. [Method] Through documentary study, individual interview and questionnaire, understand the current situation and problems of Shuangjiantiao cadres in TCM col eges. [Result] The problems in management of the said cadres are: not very reasonable post distribution, not very scientific post evaluation, not very fair post treatment and not enough post efficacies. The analysis shows the main reasons are: single subject and specialty, smal schooling scale, not enough recognition to thought and lagging team construction. [Conclusion] To improve the scientific level to the said cadres management, we shal strengthen plan and design, optimize configuration mode, insist on person fitting to post, improve competence, perfect stimulating system, improve post efficacy, pay attention to education and training and improve team qualification.
2.THE COMPARISON ON METHODS FOR ISOLATION OF NITRITE OXIDIZERS
Zhonghui ZHENG ; Yueying LIU ; Zhengping XU ; Kefu HUANG ;
Microbiology 1992;0(06):-
Three methods for isolation of nitrite oxidizers-dilution method, silica-gel plate method and enrichment culture-capillary pipette method were compared. Among them the dilution method was most feasible and efficient.
3.Determination of the Main Component of Captopril Tablets by Derivative Spectrophotometry
Zhengping XIONG ; Kaishun HUANG ; Lianlian ZHU ; Zhiqiong CHEN
China Pharmacy 2005;0(13):-
OBJECTIVE:To establish derivative spectrophotometry for the determination of the main component of Captopril tablets.METHODS:Under the alkaline condition of sodium hydroxide,2,4-dinitrofluorobenzene was used as derivatization reagent to react with captopril at 40 ℃ in the water bath.Then UV spectrophotometry was adopted to detect the content of captopril with detection wavelength set at 342 nm.RESULTS:The linear range of captopril was 1.0~14.0 ?g?mL-1(r=0.999 9) with an average recovery of 99.61%(RSD=1.27%,n=9).The RSD of intra-day and inter-day both were less than 2%.CONCLUSION:This method is stable,reliable,rapid and simple for the determination of the main components of Captopril tablets.
4.Comparative study on dissolution of strychnine in normal and ultra-micro powder of semen strychi
Long ZOU ; Hui GUI ; Shichao HUANG ; Guangxian CAI ; Zhengping TANG
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(02):-
Objective:Dissolution test was applied to study the dissolution rates of strychnine from the normal and ultramicro powder of semen strychi. Methods:HPLC techniques was used to detect the dissolution amount and the dissolution velocity of strychnine from the normal and ultra-micro powder of semen strychi. Results:The dissolution velocity of strychnine from the ultra-micro powder was higher than that from the normal powder,but there was no difference in the dissolution amount 4 hours later. Conclusion:The dissolution velocity of strychnine from the ultra-micro powder increased greatly and there was no loss of the principal active.
5.Study on pharmacokinetics of brucine from normal and ultra-micro powder of semen strychni in rats
Long ZOU ; Hui GUI ; Shichao HUANG ; Zhengping TANG ; Guangxian CAI
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(12):-
Objective:To study the pharmacokinetic process ofbrucine from normal and ultra-micro powder ofsemen strychni in rat serum.Methods:HPLC techniques were used.All pharmacokinetics parameters were calculated with a 3P87 program.Results:The pharmacokinetics results indicated that the normal powder and the ultra-micro powder ofsemen strychni belonged to two compartment open model.The absorb ofbrucine was just several ten minutes, and there was no obvious difference ofTmax between normal powder and ultra-micro powder.This showed that:Brucine was some material that was easily absorbed.But we can find that Cmax increased from(51.13?0.48)?g/L to(69.26?1.40)?g/L after ultra-micro powder preparation which was quite obvious.K,Ka,B and ? had a obvious increase(P
6.Clinical application of preoperative tumor-feeding artery embolization in treating giant meningiomas with rich blood supply
Tian TANG ; Shanzhi GU ; Guowen LI ; Manping HUANG ; Bin HUANG ; Zhengping XIONG
Journal of Interventional Radiology 2017;26(4):355-358
Objective To discuss the clinical application of preoperative tumor-feeding artery emboli -zation in treating hypervascular giant meningiomas.Methods A total of 71 patients with giant meningioma (maximum diameter >5 cm),who were admitted to authors' hospital during the period from April 2013 to August 2014,were selected for this study.Preoperative MRI demonstrated that the lesions showed obvious enhancement with rich blood supply.The patients were divided into the study group (using preoperative embolization,n =38) and the control group (not using preoperative embolization,n =33).Based on preoperative DSA findings,the lesions were classified into type Ⅰ and type Ⅱ.Tumor-feeding artery embolization with PAV particles (200-300 μm) was employed in the patients of the study group,while only cerebral angiography was adopted in the patients of the control group.The amount of intraoperative blood loss,tumor resection time and embolization complications in both groups were recorded.Postoperative MRI scan was performed to observe the degree of tumor resection.Results The amount of intraoperative blood loss and the tumor resection time in the study group were (562±178) ml and (5.45±2.13) h respectively,which in the control group were (833±234) ml and (7.23±2.45) h respectively;the differences between the two groups were statistically significant (both P<0.05).The tumor resection degree of Simpson classification Ⅲ and < Ⅲ was obtained in 27 patients of the study group (27/38,71.0%) and in 19 patients of the control group (19/33,57.6%),the difference between the two groups was statistically significant (P<0.05).After embolization,cerebral edema became aggravated in 7 patients,ischemic necrosis of the scalp was observed in 2 patients,and one patient developed epileptic seizure during the operation.After symptomatic treatment,all the above complications were relieved.Conclusion For the treatment of hypervascular giant meningiomas,preoperative tumor-feeding artery embolization can strikingly reduce the amount of intraoperative blood loss,shorten the operation time,and improve the tumor resection degree,therefore,this therapy is worthy of clinical promotion and application.
7.The efficacy of percutaneous microwave ablation for limited liver metastases of nasopharyngeal ;carcinoma
Tian TANG ; Shanzhi GU ; Guowen LI ; Manping HUANG ; Bin HUANG ; Zhengping XIONG
China Oncology 2016;26(11):943-946
Background and purpose:Since the number and tumor size of localized liver metastases can be controlled, local minimally invasive treatment can improve the survival of patients. Hence, microwave ablation has become an important treatment method for liver metastases. This study was to investigate the value of percutaneous microwave ablation in the treatment of tumor metastases. Methods: From Sep. 2011 to Oct. 2014, 26 advanced nasopharyngeal carcinoma patients with post-chemotherapy consolidation, liver metastases were collected. All the patients with the number of tumor lesions less than 3, diameter less than 5 cm, no other distant metastases was excluded. The ultrasound-guided percutaneous microwave ablation was used for 26 patients. Finally, 43 ablations were completed followed by liver function test, enhanced CT and MRI diagnosis 1 month later. mRECIST criteria was used to evaluate the effcacy of cancer treatment. Progression-free survival (PFS) and overall survival (OS) were calculated. Results:Twenty-six cases of a total of 53 lesions, including complete ablation (CA) 20 patients (20/26, 77.0%), partial ablation (PA) 3 patients (3/26,11.5%). The overall effciency was 88.5%(CA+PA) with no serious complications. 6 months, 1-, 2-year survival rates of 26 patients were 96.1%, 65.3%and 23.0%. PFS was 11.4 months. The median survival time (MST) was 11.9 months, while OS was 23.7 months. Conclusion:Percutaneous microwave ablation for limited liver metastases of nasopharyngeal carcinoma is a minimally invasive, safe and effective treatment method.
8.Surveillance of schistosomiasis in areas along water transfer project from Yangzte River to Hanjiang River in Qianjiang basin
Zongda CAI ; Zhiwu CHAI ; Qiancheng XU ; Xianguo LIU ; Shuisheng HUANG ; Zhengping ZHANG
Chinese Journal of Schistosomiasis Control 2010;22(1):81-83
Objective To evaluate the impact of the water transfer project from the Yangtze River to the Hanjiang River on the transmission of schistosomiasis.so as to provide scientific basis for the development of control strategy.Methods A field investigation on snail status,the infection situation of human and cattle as well as related endemic factors was performed in the project areas of the Qianjiang basin.Results There were 33 endemic villages and 48 non-endemic villages along the water transfer project.In endemic villages,the infection rates of human and cattle were 0.42% and 0.48%,respectively.In the endemic area,the snail area was 17.28 hm~2,the mean density of living snails was 0.043 No./0.1 m~2,meanwhile,no snail Was found in the non.endemic areas.Conclusion The surveillance on epidemic situation should be carried out for a long time in order to prevent the spreading of snails.
9.The accuracy of automated breast volume scanning for the measurement of breast tumor size
Zhengping, WANG ; Qiaoqiao, GUO ; Bifei, HUANG ; Qin, LOU ; Chao, WU ; Qiaoyang, XU
Chinese Journal of Medical Ultrasound (Electronic Edition) 2015;(6):484-487
ObjectiveTo investigate the accuracy of automated breast volume scanning (ABVS) for the measurement of breast tumor size.MethodsSixty-two breast tumors in 59 patients were included in this study and were examined using conventional ultrasound and ABVS to measure the maximal diameters of the tumors. And the measurement results were compared with the pathological maximal diameters.Results There were 21 malignant and 41 benign tumors according to histopathological evaluation. There were no signifi cant differences between the maximal diameters on ABVS and on pathological measurements for both benign tumors and malignant tumors (Z=1.761, 0.262,P=0.078, 0.794). However, for malignant tumors, the maximal diameters on conventional ultrasound were significantly smaller than those on pathological measurements (Z=3.743,P=0.000). For benign tumors, the maximal diameters on conventional ultrasound were similar with those on pathological measurements (Z=1.935,P=0.053). The measurement values of conventional ultrasound and ABVS were both positively correlated with those on pathological values (r=0.935, 0.964,r=0.870, 0.964). And the correlation coeffi cients between ABVS and pathological measurement values were higher than those between conventional ultrasound and pathological measurement values for both benign and malignant tumors. ConclusionABVS can assess the size of breast tumor more accurately than conventional ultrasound, especially for the malignant tumors.
10.Analysis on risk factor for lumbar disc herniation after decompression
Zhengping ZHANG ; Xuefang ZHANG ; Hui LI ; Tuanjiang LIU ; Qinpeng ZHAO ; Linhong HUANG ; Zijun CAO ; Limin HE ; Dingjun HAO
Journal of Regional Anatomy and Operative Surgery 2017;26(9):660-663
Objective The study aimed to identify risk factors of lumbar disc herniation in patients after decompression,and provide theoretical basis for postoperaive rehabilitation.Methods A told of 169 patients with lumbar spinal stenosis underwent bilateral partial laminectomy were included in the study,24 patients in herniation group,and 145 patients without develop postoperative acute sciatica as a control group.The radiographic variables were measured.The threshold of risk factors was evaluated by multiple logistics analysis and receiver operating characteristic curve(ROC) analysis.Results The results revealed that preoperative retrolisthesis during extension was the independent risk factor for lumbar disc herniation(1.24,95%CI[1.07~1.43];P<0.01).The area under the curve(AUC) was 0.801,and the cutoff value was 6.89%.Conclusion The preoperative retrolisthesis was the risk factor of lumbar disc herniation.