1.Application of an occupational health risk assessment method in dioctyl phthalate producing enterprise
Chengming MENG ; Peihuan QIAO ; Xiaojun LIANG ; Zhengli MENG ; Qiang LIU ; Jian SHI ; Wenhua QIN ; Linyuan ZHANG ; Shanfa YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2020;38(6):463-465
Objective:To find the risk assessment model of [di (2-ethylhexyl) phthalate, DEHP] fitting well for producing companies.Methods:The Cluster Sampling method was used in selecting a DEHP producing company in the occupational health and workplace environment monitoring study conducted between July and August in 2017. Data was collected by site evaluating and workplace environment monitoring. According to GBZ/T 298-2017《Technical Guidelines for Occupational Health Risk Assessment of Chemical Hazards in the Workplace》, a qualitative assessment method and a semi-quantitative comprehensive index method were chosen as the models and were compared.Results:The occupational health risk of the two methods rated 4 (high risk) and 2 (negligible risk) .Conclusion:The semi-quantitative comprehensive index method is more comprehensive and accurate when used to assess the occupational health risk caused by DEHP.
2.Application of an occupational health risk assessment method in dioctyl phthalate producing enterprise
Chengming MENG ; Peihuan QIAO ; Xiaojun LIANG ; Zhengli MENG ; Qiang LIU ; Jian SHI ; Wenhua QIN ; Linyuan ZHANG ; Shanfa YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2020;38(6):463-465
Objective:To find the risk assessment model of [di (2-ethylhexyl) phthalate, DEHP] fitting well for producing companies.Methods:The Cluster Sampling method was used in selecting a DEHP producing company in the occupational health and workplace environment monitoring study conducted between July and August in 2017. Data was collected by site evaluating and workplace environment monitoring. According to GBZ/T 298-2017《Technical Guidelines for Occupational Health Risk Assessment of Chemical Hazards in the Workplace》, a qualitative assessment method and a semi-quantitative comprehensive index method were chosen as the models and were compared.Results:The occupational health risk of the two methods rated 4 (high risk) and 2 (negligible risk) .Conclusion:The semi-quantitative comprehensive index method is more comprehensive and accurate when used to assess the occupational health risk caused by DEHP.
3. Determination of nitrogen oxides in the air of workplace by ion chromatography
Chengming MENG ; Zhengli MENG ; Wenhua QIN ; Shanfa YU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2019;37(12):932-935
Objective:
Improvement the method of nitrogen oxide sampling, analysis and detection in workplace air.
Methods:
Absorption and collection with sodium carbonate-sodium bicarbonate buffer solution, analysised by ion chromatography, anion column AS23, column temperature 30 ℃.
Results:
The linearity of the nitrite ion in the corresponding mass concentration range 0~90.0 μg/ml was good (Nitrogen dioxide in 0~120.0 mg/m3) , correlation coefficient>0.999 5. The detection limit was 0.16 μg/ml, The minimum detection concentration was 0.11 mg/m3 with the sampling volume 7.5 L.
Conclusion
The method has good accuracy, high sensitivity, with directing injection and no pre-treatment, and can popularize in general laboratories, and can satisfy the determination of nitrogen oxides in the air of workplace.
4.Prognostic analysis of 8 patients with hepatic adenoma undergoing allogeneic hematopoietic stem cell transplantation
Yun HE ; Zhengli XU ; Rui MA ; Jing LIU ; Yuanyuan ZHANG ; Meng LYU ; Xiaodong MO ; Chenhua YAN ; Yuqian SUN ; Xinyu ZHANG ; Yu WANG ; Xiaohui ZHANG ; Xiaojun HUANG ; Lanping XU
Chinese Journal of Hematology 2024;45(9):816-820
Objective:To evaluate the safety of patients with hepatic adenoma undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) .Methods:A retrospective analysis of the clinical characteristics and prognosis of eight patients with hepatic adenoma who underwent allo-HSCT in the Hematology Department of Peking University People’s Hospital from January 2010 to March 2024 was conducted.Results:Of the eight patients who underwent allo-HSCT with hepatic adenoma, one patient was considered MDS-h transfusion-dependent and seven had aplastic anemia. The median age of the patients was 23 years (13-48 years). The median time from the diagnosis of AA or MDS to transplantation was 14 years (6-24 years), whereas the median time from taking androgens to diagnosing hepatic adenoma was 9 years (5-13 years). Six cases underwent haplo-HSCT, one case underwent matched unrelated donor HSCT, and one case underwent matched related donor HSCT. All patients achieved neutrophil engraftment at a median time of 11.5 days (11-20 days) and PLT engraftment within 60 days at a median of 19 days (10-37 days) after haplo-HSCT. Moreover, seven patients developed CMV anemia after transplantation, three patients had hemorrhagic cystitis, and two patients developed acute GVHD. During and after transplantation, eight patients did not show severe liver function damage or rupture of hepatic adenoma. In relation to imaging size, four patients showed varying degrees of reduction in hepatic adenoma size after transplantation, whereas four patients did not show significant changes in hepatic adenoma size after transplantation. The median follow-up time was 540.5 (30-2 989) days. Of the eight patients, six survived and two died. Furthermore, no direct correlation was observed between death and hepatic adenoma.Conclusion:Patients with hepatic adenomas undergoing allo-HSCT are not contraindications for transplantation, which will not increase transplant-related mortality.