Objective: To study correlation among blood lipids and main inflammatory factors levels in patients with coronary heart disease (CHD) complicated hyperlipidemia.Methods: A total of 130 CHD patients treated in our hospital were selected.According to blood lipid level, they were divided into hyperlipidemia group (n=90) and non-hyperlipidemia group (n=40).Levels of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), high sensitive C reactive protein (hsCRP), interleukin (IL)-6 and tumor necrosis factor (TNF)-α were measured and compared between two groups.Results: Compared with non-hyperlipidemia group, there were significant rise in levels of hsCRP [(1.52±0.89) mg/L vs.(9.03±1.04) mg/L], IL-6 [(10.52±2.41) mg/L vs.(35.63±3.08) mg/L] and TNF-α [(1.04±0.04) μg/L vs.(10.08±0.25) μg/L] in hyperlipidemia group, P=0.001 all.Pearson correlation analysis indicated that levels of TC, TG and LDL-C were significant positively correlated with levels of hsCRP, IL-6 and TNF-α (r=0.603~0.843, P<0.05 or <0.01), and HDL-C level was significant inversely correlated with levels of hsCRP, IL-6 and TNF-α (r=-0.853~-0.742, P<0.01 all) in hyperlipidemia group.Conclusion: Blood lipid levels are significantly correlated with inflammatory factors levels in patients with coronary heart disease complicated hyperlipidemia.Regulation of blood lipid levels can control inflammatory factors levels, which may have an active effect on prognosis.

Objective To establish the reference interval for CA 72-4 in indirect method.Methods All results for CA72-4 that were stored in our laboratory information system of Zhongshan hospital between Jan.2010 and Dec.2012 were included in this study.Outliers were identified and omitted using Stem-and-Leaf&Box Plots in SPSS statistical software.The treated data was divided into several groups according to gender and age.Nonparametric rank sum test was used to observe the difference between male and female participants and Spearman correlation analysis was used to examine the correlation between CA 72-4 and age.Nonparametric reference intervals for CA 72-4 were estimated statistically in two gender sub-groups.Results After 139 cases excluded, there were 1 548 cases of male (Median 1.7, 0.4 to 18.9) and 773 cases of female ( Median 1.8, 0.2 to 18.9 ).There was a significant difference in serum CA 72-4 between male and female participants.No significant difference was found in serum CA 72-4 among age sub-groups.Indirect reference values for CA 72-4 of male and female were respectively 0 to 8.9 U/ml and 0 to 11.6 U/ml.Conclusion Indirect method to establish biological reference interval is a relatively simple and less expensive method under the high rapid development of the hospital information network .It can be used in the periodical review and establishing the reference intervals where the direct method can not be used.

Objective To evaluate the diagnostic and therapeutic value and safety of transcatheter arterial angiography and embolization in patients with endoscopic refractory gastrointestinal bleeding.Methods Thirty-one cases of endoscopic refractory gastrointestinal bleeding were performed DSA and treated with transcatheter arterial angiography and embolization.The safty and efficacy was evaluated.Results Angiographic positive rate of bleeding was 80.65％ (25/31);28 cases was treated with embolization.The success rate of first embolization was 75.00％ (21/28),and the total success rate was 82.14 ％ (23/28) by the second embolization.Seven patients received surgical resection after interventional therapy,including 2 cases of jejunal stromal tumors and 5 cases of gastric malignant tumors.Four cases of gastric cancer patients underwent rebleeding within 30 days after interventional therapy,of which 2 died of heart or lung function failure due to basic diseases.Except for 1 patient of anastomotic bleeding after gastrointestinal anastomosis occurred anastomotic fistula after embolization,who recovery with the support treatment,no other cases occurred serious gastrointestinal ischemic necrosis.Conclusion Interventional diagnosis and treatment for gastrointestinal bleeding hemostasis is effective and safety,and also can achieve good results especially for malignant gastric tumor hemorrhage,which can be used for endoscopic refractory gastrointestinal bleeding patients.