Humans ; Neoplasms, Cystic, Mucinous, and Serous ; pathology ; therapy ; Neuroma, Acoustic ; pathology ; therapy

Superior mesenteric vein (SMV) thrombosis is a relatively rare disease. Most patients may be successfully treated with anti-coagulation alone. However, bowel stricture may develop due to intestinal ischemia which may require surgical treatment. This report describes a rare case of small bowel stricture occurring one month after successful treatment of SMV thrombosis. After segmental resection of strictured bowel, the patient's post-operative course was uneventful.

Superior mesenteric vein (SMV) thrombosis is a relatively rare disease.Most patients may be successfully treated with anti-coagulation alone.However,bowel stricture may develop due to intestinal ischemia which may require surgical treatment.This report describes a rare case of small bowel stricture occurring one month after successful treatment of SMV thrombosis.After segmental resection of strictured bowel,the patient's post-operative course was uneventful.

Objective:To explore the osteogenic activity of in vitro cultured preosteoblasts treated by magnesium loaded hydrogel core-shell microspheres.Methods:A microfluidics chip device was designed and made to fabricate magnesium loaded hydrogel core-shell microspheres to precisely control the stable release of magnesium ions in vitro,the mechanism of controllable magnesium ion release in the promotion of osteogenic activity of MC3T3-E1 preosteoblasts was systematically investigated.Results:The magnesium loaded hydro-gel microspheres(PLGA/MgO-alginate microspheres)prepared by the microfluidics chip exhibited to be monodisperse with special core-shell structure and could control the stable release of magnesium ions at a concentration of 50 ppm in vitro.The in vitro study showed that it significantly enhanced the activity and proliferation ability of MC3T3-E1 preosteoblasts,promoted their osteogenic differ-entiation and mineralization ability,and increased ALP activity.Conclusion:Magnesium loaded hydrogel core-shell microspheres can promote the osteogenic activity of MC3T3-E1 osteoblasts in vitro.

Objective To describe and analyze the surgical outcomes of modified enlarged translabyrinthine approach (ETLA),which is combined with middle ear eradication and blind sac technique.Methods A retrospective study was conducted on 28 patients who underwent surgery for vestibular schwannoma (VS) via modified ETLA from Jan.2001 to Dec.2012.The sizes of tumors were 25-52 mn[(38.2-± 9.1)mm (x-± s)].Main outcomes measures included the rate of total removal,the rate of cerebral spinal fluid (CSF) leakage after surgery,complications,and intraoperative anatomical preservation of facial nerve and facial nerve function.Results Among the 28 patients who underwent modified ETLA,the rate of total removal was 100％.There was no death after surgery via modified ETLA.The rate of CSF leakage after surgery was 3.5％ (1/28).The rate of intraoperative anatomical preservation of facial nerve was 89.3％ (25/28).Short-term and long-term good facial nerve function rates were 25.0％ (7/28) and 42.9％ (12/28),respectively.Conclusions Modified ETLA is suitable for VS ＞ 3 cm with extension to the anterior region of cerebellopontine angle,VS involve with labyrinth part of facial nerve,high jugular bulb,preposing sigmoid sinus and highly pneumatized temporal bone.This approach can provide a wide surgical field and well prevention of CSF leakage.