1.SNP 45(T/G) of adiponectin gene polymorphism and genetic susceptibility to type 2 diabetes mellitus
Yingli WEI ; Lanjie HE ; Zhenghao HUO ; Wei ZHAO
Basic & Clinical Medicine 2006;0(09):-
Objective To investigate the relation of single nucleotide polymorphisms (SNP)45T/G the adiponectin gene with type 2 diabetes of Han nationality in Ningxia.Methods PCR-RFLP method was used to identify the distribution of alleles and genotypes frequencies of SNP45T/G polymorphisms in adiponectin gene in 100 type 2 diabetic patients and 101 normal subjects.Results The distribution of genotypes and alleles frequencies of the SNP45 polymorphisms were significantly different (GG genotype:13% vs 3%,P
2.Discussion on Laboratory Teaching of Foreign Students in Medical Cell Biology
Jie DANG ; Haiyan JIAO ; Hong LU ; Zhenghao HUO
Chinese Journal of Medical Education Research 2005;0(05):-
Objective:To improve teaching quality of laboratory teaching in medical cell biology on foreign students.Methods:To improve teaching language,teaching material,teaching methods and so on.Results:We got significant improvement on laboratory teaching of foreign students in medical cell biology.Conclusion:In order to improve teaching quality of laboratory teaching in medical cell biology on foreign students,we should improve on many different ways and accumulate experiences for future teaching.
3.Polymorphisms of (CAG)n and(GGN)n repeats of androgen receptor gene among ethnic Hui and Han Chinese from Ningxia.
Chuan ZHANG ; Mengjing GUO ; Liguo PEI ; Hao ZHU ; Fei JIA ; Lei QU ; Jie DANG ; Hong LU ; Zhenghao HUO
Chinese Journal of Medical Genetics 2013;30(3):365-369
OBJECTIVETo compare the distribution of (CAG)n and (GGN)n repeats polymorphisms of androgen receptor (AR) gene between Hui and Han ethnic Chinese from Ningxia.
METHODSGenotypes of above repeats were determined with DNA sequencing method.
RESULTSThe distribution of (GGN)n repeats was significantly different between the two ethnic groups (P< 0.01), though no such difference was detected with (CAG)n repeats (P> 0.05). Particularly, Han Chinese women carrying 23 GGN repeats were significantly fewer (48.4%) than Hui women (64.7%, P=0.01).
CONCLUSIONThe distribution of GGN repeat is significantly differently among Hui and Han Chinese ethnics from Ningxia.
Alleles ; Asian Continental Ancestry Group ; genetics ; Base Sequence ; China ; ethnology ; Female ; Genotype ; Humans ; Male ; Molecular Sequence Data ; Polymorphism, Genetic ; Population Groups ; genetics ; Receptors, Androgen ; genetics ; Trinucleotide Repeat Expansion ; Trinucleotide Repeats