1.The management of perforated duodenal ulcer in adolescence
Zhiqiang ZHENG ; Xiangyu WANG ; Min ZHENG
Chinese Journal of General Surgery 1997;0(04):-
ObjectiveTo evaluate the surgical management regarding acute duodenal ulcer perforation in adolescence.Methods24 cases underwent simple neoplasty with postoperative oral Losec for 3 months,13 cases did subtotal gastrectomy, 3 cases did vagotomy with partial gastrectomy, 5 cases did neoplasty with super-selective vagotomy.ResultsThere was no mortality, patients were followed up for 24 months. Complication rate in neoplasty group was 8.3%, and in gastrectomy group was 38.1% (P0.05).Weight gaining in neoplasty group is better than in gastrectomy group( P
2.Surgical treatment of immature teratoma in the anterior skull base with nasal cavity and paranasal sinuses involved via combined approach.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008;43(8):625-626
Adult
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Craniotomy
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methods
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Humans
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Male
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Nasal Cavity
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pathology
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Paranasal Sinuses
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pathology
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Skull Base Neoplasms
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surgery
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Teratoma
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surgery
3.A Study on the Relationship between the Expression of Matrix Metalloproteinase-9 in Rat Brain and the Pathogenesis of Epilepsy
Naizhi ZHENG ; Huijuan ZHANG ; Min WANG
Journal of Medical Research 2006;0(04):-
Objective To study the relationship between the expression of matrix metalloproteinase-9 in rat brain and pathogenesis of epilepsy.Methods The expression of matrix metalloproteinase-9 in hippocampus was observed by immunochemistry in normal and epilepsy rat.Meanwile,the effects of dexamethasone before epilepsy on the expression of MMP-9 in hippocampus was evaluated.Results The expression of MMP-9 in hippocampus were fewer in normal rat brain.The expression of MMP-9 had increased in hippocampus after epilepsy 24h.It had increased obviously in dentate gyrus(DG)after epilepsy 72h than 24h(P0.05).Dexamethasone suppressed the expression of MMP-9 in hippocampus.Conclusion The expression of MMP-9 in rat brain participates in immunopathogenesis of epilepsy by affecting brain immunoreaction,leading to the change of neuronal response and synapse remodeling in hippocampus,regulating brain nervous cell excitability.Dexamethasone plays a prominent suppressant role in the processes.
4.Treatment of Parkinson disease-like rat model by neural stem cell transplantation
Min ZHENG ; Yaping WANG ; Xuetao PEI
Basic & Clinical Medicine 2006;0(08):-
Objective To investigate the survival, differentiation and action of neural stem cell transplanted into striatum of Parkinson disease rat model. Methods Neural stem cells were isolated and cultured. The character of self-renewing was confirmed by technique of single cell clone culture. The ability of multi-directional differentiation and specific antigen-nestin was showed by immunocytochemistry(ICC). PD rat models were established, and the DAPI-labelled neural stem cells were transplanted into striatum. The 6-HHDA induced rotary behavior was measured, distribution and migration of the cell were checked by fluoresce activating. ICC and HPLC are used to see its differentiation and action of secrete neurotransmitter dopamine(DA) and it’s metabolites. Results The cultured stem cell express nestin and have the ability of self-renewing and multi-directional differentiation. 6-HHDA induced rotation decreased after transplantation of NSC into the PD rat striatum(P
5.Clinical Analysis of Hysteroscopic Resection for Submucosal Myoma of Uterus with Dipolar Electrodes: A Report of 300 cases
Qing WANG ; Min CHEN ; Ruilian ZHENG
Chinese Journal of Minimally Invasive Surgery 2005;0(09):-
Objective To evaluate advantages and safety of bipolar electrodes for the treatment of submucosal myoma of uterus.Methods Three hundred patients with submucous myoma of uterus were performed with bipolar electrodes under hysteroscope,including 212 cases of type 0 submucous myoma,54 cases of type ?,and 34 cases of type Ⅱ.Results Total volumes of uterine distention fluid used during operation were 500-2000 ml(mean,626 ml);operation time was 20-50 min(mean,25 min);intraoperative blood loss was 10-20 ml.Cardio-cerebral syndrome occurred in one case and was relieved by timely treatment.There was no operation discontinuation as a consequence of pain.The diameters of resected myomas were 3-5 cm,with an average of 3.8 cm.The postoperative diagnosis showed leiomyosarcoma in 1 case and was performed by radical hysterectomy resection combined with a pelvic lymphadenectomy at 10 day postoperatively.During the follow-up period of 1-24 months in 277 cases,40 cases(type I in 12 cases;type II in 28 cases) needed hysteroscope operation again.Conclusions Hysteroscopic resection for submucosal myoma of uterus with dipolar electrodes has advantages of safety,minimal invasion,quicker recovery,higher efficiency,so it is worthy of being recommended.
6.Clinical Significance of Hysteroscopy on the Diagnosis and Treatment of Abortive Remnants
Qing WANG ; Ruilian ZHENG ; Min CHEN
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To explore the clinical effects of hysteroscopy combined with mifepristone on the diagnosis and treatment of abortive remnants.Methods A total of 56 patients with abortive remnants,who had undergone uterine curettage after the abortion,were treated with mifepristone combined with hysteroscopy.Before hysteroscopy,mifepristone was taken orally at a dose of 100 mg daily(50 mg,Bid) for 7 days.After the surgery,those who still had remnants in the uterus were given mifepristone at the same dose for 14 days.Results No patient had complication during and after the hysteroscopy except for one,who had abortive remnants at the uterine horn,experienced blood loss of 200 ml.In 40 patients,the abortive remnants were removed completely by hysteroscopy.Two weeks after the surgery,laboratory examination of the patients showed normal blood ?-hCG,and B-ultrasonography revealed no space-occupying mass in the uterus.In the other 16 patients,remnants were detected in the uterine horns after the hysteroscopy,and mifepristone was prescribed.These patients received reexaminations 2 months after the operation,and no abnormal blood ?-hCG or remnants in the uterus was found.Among the 56 patients,33 were followed up for 1-6 months(mean,3 months).During the follow-up,their symptoms including vaginal bleeding or drainage,amenorrhea,and abdominal pain disappeared,and the menstruation became normal.Conclusions Hysteroscopy combined with mifepristone is an effective measure to diagnose and treat abortive remnants.
7.Comparison of clinical effects of different kinds of gingival retraction technique in treatment of anterior teeth restoration
Min ZHENG ; Hui WANG ; Quan ZHOU
Chinese Journal of Primary Medicine and Pharmacy 2016;23(2):249-252
Objective To compare the clinical effects of four kinds of gingival retraction technique in treat-ment of anterior teeth restoration.Methods 169 patients for 352 teeth with tooth body and tooth dentition defect by anterior crown bridge repair were chosen and divided into 4 group by patients'order,including A group(88cases)with single track method,B group(91cases)with single line for two times method,C group(89cases)with double line method and D group(94cases)with double line for two times method.And the fixed restoration satisfaction rate of anterior teeth of both groups was compared.Results The satisfaction rates of gums,shoulder,impression,model and restoration of A group were 73.9%,70.1%,69.3%,65.9%,61.4% respectively,which of B group were 83.5%, 80.2%,80.2%,80.2%,76.9%;which of C group were 84.3%,80.9%,78.7%,77.5%,76.4%;which of D group were 94.6%,93.6%,92.6%,92.6%,90.4%.There were no significant differences in the fixed restoration satisfaction rate of anterior teeth between B group and C group(χ2 =2.43,1.17,2.85,3.04,2.30,all P >0.05). The fixed restoration satisfaction rate of anterior teeth of D group were significantly better than A,B and C groups (χ2 =14.90,16.39,15.83,19.87,21.38,all P <0.05 ).Conclusion Double line for two times method in the treatment of anterior teeth restoration can efficiently avoid ree gingival damage in the situation with abutment shoulder preparation,improve the quality of preparation,impression and model,and are helpful to higher the fitness of the neck of anterior teeth fixed restorations.
8.Teaching innovation of morphologic experiment—setting up of morphologic experimental centre
Rong JIANG ; Min ZHENG ; Weiwei WANG
Chinese Journal of Medical Education Research 2006;0(08):-
The setting up of morphologic experimental centre has brougt experimental methods and means to a higher level. However, it is worth considering how to share the resource furthest,and how to exert experimental technicians’ efforts. This article intends to discuss those problems.
10.Survey on Sleep Quality and Mental Health of Nurses
Li CHEN ; Feizhong ZHENG ; Min WANG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(6):585-587
Objective To investigate the relationship between sleep quality and mental health in the nurses.MethodsThree groups subjects, 53 students of nursing college, 57 advanced students receiving clinical training and 61 clinical nurses, were investigated with the Pittsburgh Sleep Quality Index (PSQI) and Self Checklist-90 (SCL-90). The standard of having sleep problem was PSQI scores ≥8.ResultsThere were 20.05% of subjects having sleep problem. The total score of PSQI was significantly different among three groups ( P<0.001), but total score of SCL-90 of three groups was not different. The total score of PSQI was correlated positively with the total score of SCL-90.ConclusionSleep quality and mental health are affected each other, and sleep quality is declining gradually from students in nursing college to clinical nurses, but there aren't obvious changes in mental status.