1.Assistive Technology Act of the USA and Enlightenment for China
Chinese Journal of Rehabilitation Theory and Practice 2007;13(4):319-321
Assistive Technology Act of the USA is a very important law for the persons with disability in USA. The background of the Assistive Technology Act of the USA was reviewed and the guarantee of laws for the disabilities was discussed in the paper. From which, some theory and practice for special education of China can be obtained, and some experience and enlightenment for setting up related laws in China also can be worked out.
2.American Job Accommodation: Political Strategies and Methods
Chinese Journal of Rehabilitation Theory and Practice 2012;18(5):487-489
Job Accommodation of American is effective to ensure the equal employment of domestic disabilities. This paper introduced its legal basis, contents and procedures.
3.Methods and experiences of nursing post management of the hospital
Jian ZHANG ; Yining ZHENG ; Jian LIU
Chinese Journal of Hospital Administration 2012;28(8):618-619
The paper presented the methods and experiences of managing nursing posts in Beijing Friendship Hospital.As introduced in the paper,such measures as conversion of organizational structure,innovative nursing post setup,new training model,dynamic allocation of nursing manpower,and effective performance incentive mechanism,promoted better nursing quality and stabilized nursing team,achieving sustainable development of quality nursing service.
4.Association analysis between Alzheimer's disease and the promoter polymorphism of PSEN2 gene
Chinese Journal of Neurology 2001;0(01):-
Objective Alzheimer's disease (AD) is the most common neurodegenerative disorder of aging.Identifying novel AD genetic risk factors is important for understanding its pathogenesis.Presenilin- 2 (PSEN2) is one of the causative genes for familial AD.Polymorphism of the promoter region of PSEN2 has recently been reported to be associated with sporadic AD in a Russian population.The purpose of this study was to determine whether AD is associated with the PSEN2 gene polymorphism in a case-control study.Methods We examined PSEN2 and ApoE genotypes of 160 patients with AD and an equal number of age- and sex-matched controls from the same community by using PCR-RFLP method.Statistical analyses included a Chi-square test for homogeneity and a Logistic regression analysis.Results Examination of PSEN2 genotypes revealed no statistically significant differences in the frequency of the+A/-A polymorphism when compared with the total sample of AD patients and control individuals (P=0.11). However,subgroup of ApoE 84 non-carriers suggested significant differences of the three genotypes of PSEN2 promoter between AD and controls (P=0.038).Logistic analyses indicated ApoE genotypes were related with AD,and after stratification by e4 allele,PSEN2 genotypes were related with AD of e4 non-carriers.In addition,there was no interaction between ApoE and PSEN2 gene.Conclusion The+A/-A polymorphism of PSEN2 promoter may be a minor genetic risk factor for sporadic AD,especially in the group of AD without ApoE ?4 allele.
6.Influences of nasal continuous positive airway pressure to sleep architecture of obstructive sleep apnea syndrome.
Zhiyang LUO ; Guocui ZHENG ; Jian LIU
Chinese Journal of Practical Internal Medicine 2001;0(07):-
Objective To investigate influences of nasal continuous positive airway pressure to sleep architecture of obstructive sleep apnea syndrome and the reason of daytime sleepiness. Methods 34 patients with severe OSAS were monitored with polysomnography (PSG) before and after nCPAP treatment. Results Apnea hypoventilation index (AHI) decreased and the lowest SaO2 increased and sleep architecture was improved in all patients. Conclusion The nCPAP therapy can effectively improve the disturbances of sleep architecture and respiratory parameters.
7.Change and its significance of serum neuron-specific enolase level at acute stage of stroke
Jianmin LIU ; Zhujuan ZHOU ; Jian ZHENG
Journal of Clinical Neurology 1997;0(06):-
Objective To explore the relationship between the serum neuron-specific enolase(NSE) level and stroke region and size,the degree of neurological deficit and prognosis at acute stage of stroke.Methods The level of serum NSE was detected by ELISA in 96 stroke patients at acute stage,including 58 cases of cerebral infarction (CI),27 cases of intracerebral hemorrhage(ICH),11 cases of subarachnoid hemorrhage (SAH) and 25 normal controls(NC group).The relationship between the level of serum NSE and China Stroke Score (CSS),Barthel index(BI),score of Glasgow-Pittsburgh Coma Scale,lesions region and volume were analysed among the various stroke types groups.Results The levels of serum NSE in the stroke patients at acute stage were significantly higher than that in NC group (allP
8.Study on Water-soluble Components of Red Ginseng
Lu ZHENG ; Jian ZHENG ; Qingrong LIU ; Qiuzhu TANG ; Yuzhen LIU ; Yinan ZHENG ;
Chinese Traditional Patent Medicine 1992;0(12):-
Objective:? N oxalo L ?,? diaminopropionic acid were isolated from the powder of red ginseng. its physiological characteristics were studied. Method:This material is obtained by CM Sephadex C 25 and FPLC MonoQ. We have examined the effect of ? N oxalo L ?,? diaminopropionic acid on contraction of artery of guinea pig. Result:When histamin and adrenalin do not exist, there is neither contraction nor relaxation. It can strengthen induction of contraction of artery of guinea pig, but it has no such effect on adrenalin. Besides, it doesn't induce plaque coagulation through adrenalin, ADP blood coagulation enzyme and collagen. It doesn't suppress the transformation from tension peptide of blood vessel to enzyme.Conclusion:Hemostatic effect of ? N oxalo L ?,? dlaminopropinomie acid may caused by vesseles contraction through promoting Histamine.
9.Correlation Study Between Serum Soluble ST2 Level and the Early Clinical Prognosis in Patients With Acute ST-elevation Myocardial Infarction
Lei HE ; Jian PENG ; Xuan ZHENG ; Chengwei LIU ; Xi SU
Chinese Circulation Journal 2017;32(1):41-45
Objective: To preliminarily investigate the relationship between the baseline level of serum soluble ST2 (sST2) and 30-day MACE occurrence rate in patients with ST-elevation myocardial infarction (STEMI).
Methods: A total of 121 patients with confirmed diagnosis of STEMI in our hospital from 2015-05-01 to 2015-07-30 were consecutively enrolled. According to baseline sST2 level, the patients were divided into 2 groups:Low sST2 group, the patients with sST2≤56.68 ng/ml, n=61 and High sST2 group, the patients with sST2>56.68 ng/ml, n=60. Clinical condition and 30-day MACE (defined as death and new onset of congestive heart failure) occurrence rate were compared between 2 groups.
Results: ① The systolic blood pressure (SBP), Killip class≥II grade, blood levels of cTNI, NT-proBNP, hs-CRP and LVEF were different between 2 groups, all P<0.05. ② Baseline sST2 level was positively related to heart rate (r=0.271, P=0.003), Hs-CRP (r=0.359, P=0.000), cTNI (r=0.324, P=0.000) and NT-proBNP (r=0.425, P=0.000);negatively related to SBP (r=-0.226, P=0.013) and LVEF (r=-0.406, P=0.000).③30-day MACE occurrence rate was different between 2 groups (8.2%vs 30%, P=0.002). ④ Multivariate Cox regression analysis presented that sST2>56.68 ng/ml was the risk factor for 30-day MACE occurrence (HR=1.152, 95%CI 1.078-1.231, P=0.000).
Conclusion: Increased baseline level of sST2 implied the higher incidence of death and new onset of congestive heart failure in STEMI patients.
10.Application value of Hcy and IMA in the diagnosis of AMI
Liangeng LIU ; Hailing LU ; Xingzhong ZHENG ; Jian WU
International Journal of Laboratory Medicine 2016;37(18):2517-2519
Objective To investigate the significance of combined detection of homocysteine(Hcy) and ischemia modified albu‐min(IMA) in serum to the diagnosis of acute myocardial infarction(AMI) .Methods The serum levels of Hcy and IMA were detec‐ted in 80 patients with acute myocardial infarction ,60 patients with angina pectoris and 40 healthy subjects(control group) ,and the results were statistically analyzed .Results The concentration of Hcy and IMA in AMI patients was significantly higher than which in the control group ,the difference is statistically significant(P<0 .05);the sensitivity of the Hcy+ IMA combined diagnosis was higher than that of the single project .Hcy and IMA was positively related(P<0 .05) .Conclusion The combined detection of Hcy and IMA levels in patients with acute myocardial infarction has a good effect on early diagnosis and monitoring ,and it is worth popularizing .