1.Advances in origin and pathogenesis of epithelial ovarian cancer.
Chinese Journal of Pathology 2011;40(8):569-572
Adenocarcinoma, Clear Cell
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etiology
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pathology
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Brenner Tumor
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etiology
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pathology
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Carcinosarcoma
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etiology
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pathology
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Cell Transformation, Neoplastic
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Cystadenocarcinoma, Serous
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etiology
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pathology
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Epithelial Cells
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metabolism
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pathology
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Female
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Genes, p53
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Humans
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Mutation
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Neoplasms, Glandular and Epithelial
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etiology
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genetics
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metabolism
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pathology
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Ovarian Neoplasms
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etiology
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genetics
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metabolism
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pathology
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Tumor Suppressor Protein p53
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genetics
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metabolism
2.Principle of Newport E360 Ventilator
Guojian WEN ; Feng ZHENG ; Manfang LIU
Chinese Medical Equipment Journal 2003;0(10):-
The inhalation,exhalation,electronics system and clinical application of Newport E360 ventilator are introduced.Study and technical analysis are given on the working principles of dual servo gas delivery system(one for air and the other for oxygen).The safety system and circuit system are studied and analyzed to provide reference for engineers in equpiment department in hospital.
3.The effective of FGF-23(R176Q)overexpress in adult mouse mandible formation and mineralization
Hong LIU ; Wen SUN ; Yangyu ZHENG
Chongqing Medicine 2015;(7):888-890
Objective To investigate the effective of FGF-23(R176Q)overexpression of adult mouse mandible formation and mineralization.Methods CT scanning,serological examination,HE staining,immunohistochemical staining and RT-PCR analysis were used to compared mandible of FGF-23(R176Q)transgenic mice(TG group)and wild type mice(WT group),serum calcium and phosphorus concentrations mandibule formation and mineralization were analysised.Results Serum calcium,phosphorus and 1, 25(OH)2 D3 concentrations in WT group were significantly higher than that in TG group,the difference was statistically significant (P <0.05);the Ob.s/B.Pm TG group was lower than that of WT group,the difference was statistically significant(P <0.05);the positive percentage of Biglycan in TG group was higher than that in WT group,the difference was statistically significant(P <0.05);the OCN and type I collagen mRNA levels in the WT group were significantly higher than that in TG group,the difference were statistically significant(P <0.05).Conclusion FGF-23(R176Q)overexpression can inhibit the formation of mandible,reduce the formation of mineralized,and reduce the development of the mandible.
4.Computer-aided Diagnosis of Gastric Carcinoma B ased on Feature Selection and Probability Neural Network
Jun LIU ; Wen-Li MA ; Wen-Juan YAO ; Wen-Ling ZHENG
Progress in Modern Biomedicine 2008;8(5):924-927
Based on signal to noise ratio and probabilistic neural network method associated with experimental data,all analysis model in gastric carcinoma is presented.According to the available information,the samples of gastric carcinoma can be tested and ana.Lyzed.The signal to noise ratio is first calculated.Secondly,records in the database are chosen as a training set to build a probabilistie neural network model and the feature subset is selected according to accuracy.Finally,test set is to test accuracy of model.The model is implemented using MATLAB,and it can be generalized and applied to similar disease auxiliary diagnosis region.
5.Role of Leukocyte Activation and Inflammatory Reaction in Chronic Venous Insufficiency
Xue-Gang WEN ; Yan-Zheng HE ; Yong LIU ;
Chinese Journal of Bases and Clinics in General Surgery 2003;0(03):-
Objective To discuss the role of leukocyte activation and inflammatory processes in the disease of chronic venous insufficiency(CVI).Methods The relevant literatures about the role of leukocyte activation and in- flammatory reaction in CVI were reviewed.Results The role of inflammatory reaction in occurrence and develop- ment of venous diseases has been studied a lot in recent years.It was found that the leukocyte activation and inflam- matory reaction are involved in the structural remodeling of venous valves and walls,leading to valvular incompe- tence and formation of varicose veins.Conclusion Leukocyte activation and inflammatory processes take important roles in the occurrence and progression of CVI.
6.Silicone elastomers for maxillofacial prosthesis
wen-juan, LIU ; yuan-li, ZHENG ; jing, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(10):-
Current materials used for maxillofacial prostheses are far from ideal,and how to develop a final prosthetics material is a significant topic in the research of maxillofacial prostheses.In this paper,some pertinent research of silicone elastomeric materials,such as mechanical properties and colorant are reviewed.
7.Value of blood culture result in guiding clinical rational use of antimicrobial agents in clinic
Juan LI ; Nuo ZHENG ; Wen LIU ; Zhifeng LI
International Journal of Laboratory Medicine 2017;38(9):1209-1210,1213
Objective To investigate the value of blood culture result in guiding clinical rational use of drugs in clinic.Methods The medical records of 100 children patients with blood culture positive in the four departments of our hospital were retrospectively analyzed.Results The empirical treatment accounted for 98%,the goodness of fit in the medication before culture with the appropriate antibacterial drugs according to final detected bacteria was only 51.6%;after issuing the level 1 report,the adding and substituting drugs in adjusting the antibacterial drugs accounted for about 20% each,60% of antibacterial drugs were not adjusted;after issuing the level 2 report,about 5% of children patients added the antibacterial drugs,the proportion for replacing antibacterial drugs reached 32%,meanwhile the proportion for reducing accounted for 3%;after issuing the level 3 report,the consistency of antibacterial drugs use with the final drug susceptibility test results reached 83%,the inconsistency was only about 5%.Conclusion Clinical pediatric doctors in this hospital still heavily rely on the results of blood culture 3 levels reports,executing antibacterial agents from the experience treatment to the target treatment is also very active.
8.Expression of SCC-Ag and CEA and its clinical significance in patients with lung cancer
Xiaoling LIU ; Tao WANG ; Wen WANG ; Ying JIANG ; Wei ZHENG
Journal of Xi'an Jiaotong University(Medical Sciences) 2004;0(05):-
Objective To investigate the ex pr ession of squamous cell carcinoma antigen (SCC-Ag) and carcinoembryanic antigen (CEA) and its clinical significance in patients with lung cancer. Meth ods The pre-treatment serum from 134 patients with lung cancer from 1998 to 2002 were analyzed for the SCC-Ag level and CEA level by IMX, and the correlation of the SCC-Ag level and CEA level with the clinicopathologic charac teristics were also detected. Results Significant correlations were found between the pre -treatment SCC-Ag level, and CEA level and the pathologic classification, clin ical stage, the positive rate of diagnosing lung cancer was raised by combined a ssay with serum SCC-Ag and CEA. Conclusion Pre-treatment and after-treatment measurement of serum SCC-Ag level and CEA level can be used for diagnosis, prediction of pr ognosis and monitor of after-treatment recurrence in patients with lung cancer.
9.The clinical significance and the relationship between the serum squamous cell carcinoma antigen level and the biological characteristics of cervical carcinoma
Xiaoling LIU ; Shaomin CHE ; Wen WANG ; Ying JIANG ; Wei ZHENG
Journal of Xi'an Jiaotong University(Medical Sciences) 2003;0(06):-
Objective To investigate the clinical significa nc e and the relationship between the serum squamous cell carcinoma antigen (SCC-A g) levels and the biological characteristics in patients with cervical carcinoma . Methods The pre-post-treatment sera from 500 patients w ith cervical carcinoma from 1998 to 2002 were analyzed for the SCC-Ag levels by IMX; and the correlation between the SCC-Ag level and the clinicopathologic ch aracteristics were also detected. Results Significant corre lation was found between the pre-treatment SCC-Ag level and pathologic classif ication, and clinical stage (P0.05); The pre-treatm ent SCC-Ag level is significantly higher than that of post-treatment (P
10.Trend of treatment and rehabilitation rates among people with psychiatric disability from 2007 to 2013 in China
Tianli LIU ; Gong CHEN ; Xu WEN ; Xiaoying ZHENG
Chinese Mental Health Journal 2017;31(3):195-202
Objective:To describe health service use and trend of treatment and rehabilitation rates among people with psychiatric disability from 2007 to 2013.Methods:Data collected by the 2006 Second China National Sample Survey and the 2007-2013 National Disability Monitoring Survey were utilized and analyzed.The 2006 National Sample Survey on Disabilities investigated 2 526 145 non-institutionalized representative civilians in 734 counties across mainland China.Psychiatric disability was diagnosed by clinical psychiatrists according to ICD-10 and WHO DAS Ⅱ criteria.The 2007 to 2013 National Disability Monitoring Survey selected 1 to 2 study sites among each of the 734 study counties that had been investigated by the Second China National Sample Survey.Information on living conditions,health service use,education and employment were recorded.Results:The data showed that treatment and rehabilitation rates for people with psychiatric disability had largely increased from 2007 to 2013 among adults aged 18 years or older,with the treatment and rehabilitation rates from 49.52% and 21.8% to 66.9% and 58.7% respectively,and the rates among those with 17 years or younger from 23.5% to 43.9%.However,with regard to the effect of the treatment and rehabilitation services,a much larger proportion of people with psychiatric disability reported that the effect was soso instead of good or very good.In addition,among those who received rehabilitation service,most received day care or psychotherapy service,only less than 8% participated work therapy,farming therapy or working skill trainings.Conclusion:The results suggest treatment and rehabilitation rates among people with psychiatric disability are largely increased from 2007 to 2013,while the quality of the service needs further attention.