1.Social Support in Students of Normal College
Wen ZHANG ; Guanghui QI ; Richang ZHENG
Chinese Mental Health Journal 2001;15(2):81-82,87
Objective: To explore how social support in students of normal college related to their interpersonal attribution and philosophies of human nature, and whether social support varied with different subgroups. Method: Social Support Rating Scale, the Multidimentional-Multiattributional Causality Scale and Revised Philosophies of Human Nature Scale were used in 414 students of a normal university. Result: The social support of students differed significantly among different departments, students of science had lower social support than students of art or sport had. There was no significant difference of social support between sexes, different grades, of urban or rural area. Social support was significantly correlated with "effort" attribution of interpersonal relationship, but not with "ability, background or luck". Social support was positively related to trustworthiness, while negatively to cynicism. Conclusion: This result fits for the common sense of Chinese and people elsewhere.
2.Dynamic study of graft regeneration after right lobe adult living donor liver transplantation
Qian JI ; Zhiqiang CHU ; Wen SHEN ; Hong ZHENG ; Ji QI
Chinese Journal of Organ Transplantation 2014;35(4):198-201
Objective To evaluate graft regeneration and influencing factors after right lobe adult living donor liver transplantation (LDLT) using MSCT.Method Sixty-three living recipients were included in this study.We measured graft volume periodically by using MSCT and IQQA-Liver workstation.The liver regenerative ratio (LRR) of different stages of recipients after LDLT was calculated and compared,and stepwise regression analysis was done to set up the regression equation.Result Within 0.5 month after LDLT,graft volume was increased rapidly,and LRR reached maximum [(106.11 + 30.90)%],then decreased slowly.There was significant difference in LRR among 0.5,1 month and 3,6 months after LDLT (P<0.05).The following factors,including whether the graft containing middle hepatic vein or not,age and sex of recipients,had no significant influence on LRR after LDLT (P>0.05).The status of liver function of recipients preoperatively had significant influence on LRR 0.5 month after LDLT (P<0.05).There was significantly negative correlation between the graft volume and LRRs of recipients at different stages after LDLT (P < 0.05).Regression equation could be derived.Conclusion Most evident graft regeneration occurs in early stage after adult LDLT.There are many and different factors influencing graft regeneration at the different stages after LDLT.Graft volumetric measurement by using MSCT is a valid modality to evaluate graft regeneration after LDLT.
3.Impact of donor age on graft short-term outcome after right lobe adult living donor liver transplantation
Qian JI ; Zhiqiang CHU ; Wen SHEN ; Hong ZHENG ; Ji QI
Chinese Journal of Organ Transplantation 2014;35(7):413-415
Objective To evaluate the impact of donor age on graft short-term outcome after right lobe adult living donor liver transplantation (LDLT).Method Thirty living recipients were divided into 2 groups according to donor age:older donor group (O group,donor age >50,n =5) and younger donor group (Y group,donor age <30,n =25).Alanine transarninase (ALT),aspartate transaminase (AST),total bilirubin (TB),prothrombin time (PT) on the postoperative day 1 to 5 and graft liver regenerative ratio (LRR) on the postoperative month 0.5,1,3,and 6 between 2 groups were determined and compared.Result TB on postoperative day 1,2,3,4 and 5 was significantly higher in O group than in Y group there were significant differences between two groups (P<0.01).There was no significant difference of other liver function parameters 2 groups (P > 0.05).There was no significant difference in LRRs on the postoperative month 0.5,1,3 and 6 months postoperatively between 2 groups after LDLT (P>0.05).Conclusion Although allografts from older donors in LDLT have prolonged jaundice than those of their younger counterparts,after strictly preoperative evaluation,donor age has little effect on short-term outcomes of graft after LDLT.
4.The impact of donor age on early remnant liver function and regeneration after right lobe graft donation
Qian JI ; Zhiqiang CHU ; Wen SHEN ; Hong ZHENG ; Ji QI
Chinese Journal of General Surgery 2014;29(11):821-823
Objective To evaluate the impact of donor age on early remnant liver function and regeneration after right lobe adult living donor liver transplantation (LDLT) donation.Methods 43 living donors were divided into 2 groups:donor age > 50,n =8,and donor age < 30,n =35.Alanine aminotransferase (ALT),aspartate aminotransferase (AST),total bilirubin (TB) and liver regenerative ratio (LRR) of donors between the 2 groups were compared.Results There were no significantly different in ALT,AST and TB on days 1,2,3,5 after LDLT between the 2 groups (respectively t =0.147,1.030,-0.903,0.013,0.043,1.362,0.817,0.003,1.121,0.241,1.061 and 0.943,all P>0.05).There was significant difference between LRR on day 7 (t =-0.965,P =0.042),but the difference was not statistically significant in LRR when evaluated on day 15 after LDLT (t =0.585,P =0.385).Conclusions Remnant liver regeneration on the first week is reversely affected by donor's age after hepatectomy,while the influence of age decreases significantly after 2 weeks.
5.A study on donor remnant liver regeneration after right lobe adult living donor liver transplantation
Qian JI ; Zhiqiang CHU ; Wen SHEN ; Hong ZHENG ; Ji QI
Chinese Journal of General Surgery 2014;29(6):444-447
Objective To evaluate donor remnant liver regeneration and influencing factors at different stages after right lobe adult living donor liver transplantation (LDLT) using multi-slice spiral computed tomography (MSCT).Methods 68 living donors were included in this study,We did CT volumetric measurement of the liver by using IQQA-Liver workstation.Liver regenerative ratio (LRR) at different stages of donors after LDLT were calculated and compared,correlation coefficient and stepwise regression analysis were calculated.Results The difference between LRRs at different stages after LDLT were significant (F =3.323,P =0.009),there were significant difference between LRR of 7-day and 1-month,3-month (respectively t =-2.065,-2.214,all P < 0.05).The inclusion of middle hepatic vein and donor gender had no influence on LRR (respectively t =0.600,-0.622,1.464,0.926,-1.228,0.624,-0.688,0.131,all P > 0.05).There were negative correlation between the remnant liver volume and LRRs (P < 0.05).Conclusions MSCT is a valid modality to evaluate remnant liver regeneration after LDLT.Most evident remnant liver regeneration occurs in early stage after adult LDLT.
6.Cerebral metabolic changes in cirrhotic patients before and after liver transplantation: a MR spectroscopy study
Bin JIANG ; Wen SHEN ; Longjiang ZHANG ; Jianzhong YIN ; Hong ZHENG ; Ji QI
Chinese Journal of Radiology 2010;44(10):1054-1060
Objective To quantitatively evaluate the metabolic changes in posterior cingulated cortex and left basal ganglia in patients with liver cirrhosis before and after liver Transplantation (LT).Methods A total of 22 controls and 37 cirrhotic patients listed for LT were enrolled in the study. Brain MRS (PRESS sequence) and neuropsychological (NP) tests were performed in all subjects. Eighteen patients were followed up at 1 month and 3 month after LT. The NP parameters including number connection test-A ( NCT-A), digital symbol test (DST) and symbol digital test (SDT) were measured. MRS metabolic contents were measured automatically at posterior cingulate cortex (PCC) and left basal ganglia (LBG).Independent t-test was used to compare the parameters of NP test and MRS metabolites between the 2 groups. The changes of the parameters before and after LT were compared using analysis of variance.Pearson correlation test was also used to analysis the relationship between NP test parameters and MRS metabolites. Results ( 1 ) Before LT, significant difference of metabolites was found in the PCC between the two groups [ NAA/Cr(1.96 ±0.21, 1.73 ±0. 12), Cho/Cr(0. 65 ±0. 12,0. 83 ±0.09), mI/Cr (0.41 ±0.14,0.72±0.11), Glx/Cr(2. 37 ±0. 38,1. 92 ±0. 32) (t= -5.42,5.96,8.62,-4.72,P<0.01)].And statistical significance also were found in LBG between the 2 groups [ Cho/Cr (0. 63 ± 0. 16,0. 77 ±0. 10), mI/Cr(0.38 ±0. 17,0.53 ±0.21), GIx/Cr(1.70 ±0.36,1.29 ±0.30), (t =3.64,3.07,-4.58 ,P < 0. 01 )]. (2)Compared with controls, the patients before LT had longer NCT-A reaction time [ (58. 17 ±19. 12) s,(37.68 ±8.02) s,t =4. 14,P<0.01], lower scores of DST (36.67 ±9.91,55.36 ±9.27,t = 4.60,P<0.01) and SDT (31.67 ±9.49,50.73 ±8.34,t = 4.652,P<0.01) before LT. All the scores of NP tests changed significantly at 1 and 3 month after LT compared with those before LT[ NCT-A (53.06±12.71) s,(35.72 ±5.20) s,F =33.554,P <0.01 ], DST(41.89 ±8. 17,54.39 ±5.69,F =85.772,P<0.01),SDT(37.44±7.68,49.39±5.65,F=83.061,P<0.01)]. (3) In the 18 patients who were followed, Cho/Cr [ PCC (0. 90 ± 0. 14,0. 92 ± 0. 08, F = 38. 178, P < 0. 01 ); LBG (0. 81 ± 0. 08,0. 80 ±0.09,F =9.447,P <0.01)] and Glx/Cr [ PCC(1.86 ±0.32,1.75 ±0.25,F = 19.420, P <0. 01 ); LBG( 1.30 ±0. 20,1.23 ±0. 25 ,F = 17. 952,P <0. 01 ) ] recovered at 1 month after LT, while the mI/Cr [PCC (0.39±0.15,0.71 ±0. 10,F =75. 186,P<0.01) ;LBG (0.47 ±0.25,0.61 ±0.27,F =8. 027, P < 0. 01 ) ] recovered at 3 month after LT. (4)mI/Cr of cingulate cortex correlated significantly with NCT-A, DST and SDT (r= -0.743, 0.597, 0.615, P<0.01 ) before LT. Conclusion Cerebral metabolic changes in patients with liver cirrhosis is reversible and MRS of the posterior cingulate cortex is a helpful method in following up the changes after LT. mI/Cr is a useful indicator to predict the brain changes of cirrhotic patients before and after LT.
7.Clinical and imaging study on hepatic venous congestion of Ⅴ, Ⅷ segments in living donor liver transplantation
Qian JI ; Zhiqiang CHU ; Wen SHEN ; Zhijun ZHU ; Hong ZHENG ; Yonglin DENG ; Ji QI
Chinese Journal of General Surgery 2011;26(4):320-323
Objective To evaluate MSCT appearance and impaction of Ⅴ, Ⅷ segments' hepatic venous congestion ( HVC ) on hepatic functional recovery in living donor liver transplantation (LDLT).Methods In this study, 83 patients undergoing LDLT in our hospital were included, all subjects received plain and contrast MSCT examinations at early stage (within 1 month) and later stage (3 months later) after LDLT. MSCT appearance of HVC was recorded, at the same time, gutamic pyruvic transaminase ( ALT),glutamic oxalacetic transaminase (AST), total bilirubin (TB) and prothrombin time (PT) of 1 to 7 days after LDLT between congestion group and non-congestion group were recorded and compared.Results Segments Ⅴ and Ⅷ congestion was identified by after LDLT CT scanning in 20 patients (24. 10% ). Congestion volume and congestion ratio was (218. 25 ± 130. 29) cm3 and 16. 68% ±8. 81%,respectively. HVC often appear as hypoattenuation on plain CT scan and arterial phase, mixed or hyperattenuation on portal vein phase. There was no significant difference of ALT, AST, TB and PT after LDLT between congestion group and non-congestion group (P > 0. 05). Conclusions MSCT is a valuable method to evaluate Ⅴ, Ⅷ segments' HVC after LDLT, most HVC has no impaction on hepatic functional recovery in LDLT patients.
8.Clinical characteristics in 18 cases of sever pneumonia after allogeneic hematopoietic stem cell transplantation for malignant hematological disease.
Journal of Experimental Hematology 2004;12(4):517-518
To investigate the clinical features and outcome of severe pneumonia after allogeneic hematopoietic stem cell transplantation for malignant hematological disease, the clinical features of severe pneumonia, including symptoms, signs, blood-gas analysis and thoracic X-ray change were observed, the clinical therapeutical outcome is also evaluated. The results showed that after treatment with antibiotics or antibiotics + antiviral drugs or antibiotics + antiviral drugs + glucocorticosteroids, as well as mechanical ventilation, pulmonary changes in 17 patients with sever pneumonia completely disappeared, 1 case died. In conclusion, early diagnosis and proper treatment for complicated pneumonia after allogeneic hematopoietic stem cell transplantation can decrease the mortality.
Adolescent
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Adult
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Female
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Hematologic Neoplasms
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therapy
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Hematopoietic Stem Cell Transplantation
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adverse effects
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Humans
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Male
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Middle Aged
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Pneumonia
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diagnosis
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etiology
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therapy
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Transplantation, Homologous
9.Feasibility Research of Determined Oxygen Permeability of Finished Soft Contact Lens.
Yan WEN ; Jian ZHENG ; Honqping FANG ; Xiaohang JIA ; Tao HE ; Weiming QI
Chinese Journal of Medical Instrumentation 2015;39(2):136-138
OBJECTIVEA method for determined oxygen permeability (Dk) of finished soft contact lens.
METHODSOxygen permeability(Dk) of 10 group finished soft contact lens was determined by polarographic method, and the values were linearly calibrated using the measured and established Dk values of the specified reference materials.
RESULTSOnly one Dk value fell outside of the requirement of GB 11417.3-2012 tolerance for Dk (± 20%).
CONCLUSIONIt is great practicability when determined the oxygen permeability (Dk) of finished soft contact lens by polarographic method which were linearly calibrated using the measured and established Dk values of the specified equal thickness reference materials without the measured lens customized 4 different thickness.
Calibration ; Contact Lenses, Hydrophilic ; Oxygen ; metabolism ; Permeability ; Polarography
10.Clinical observation of phakic intraocular lens implantation for patients with extreme highly myopia
You-Ping, ZHENG ; Xiao-Tao, WU ; Qi-Wen, LI ; Jing-Xiang, ZHONG ; Gui-Fang, WANG
International Eye Science 2015;(5):933-935
?AlM: To evaluate the clinical effects and security of posterior chamber implantable Collamer lens ( lCL ) implantation in patients with extreme highly myopia.
?METHODS:ln this study, 18 patients ( 32 eyes ) with extreme highly myopic patients who had undergone posterior chamber lCLs implantation from July 2010 to July 2013 were evaluated. Diopter -10. 5 ~ 19. 0D, and astigmia -0. 5 ~4. 5DC. Changes in intraocular pressure ( lOP ) , refraction, visual acuity and corneal endothelium, anterior chamber depth, iris, high arch, lens were noted at 1d, 1wk, 1, 3mo and 1a after surgery respectively, and follow-up was of 1a.
? RESULTS: Before surgery, the uncorrected visual acuity (UCVA) were 0. 01~0. 05, and the best spectacle-corrected visual acuity ( BSCVA) were 0. 4 ~ 1. 0. One month after surgery, the UCVA were 0. 5~1. 2. The mean vault were 547±222 μm (95%CI 442~672μm) and 528±268μm (95%CI 354 ~635μm) for 1mo and 1a, respectively (P = 0. 81), and there was no significant difference. Anterior subcapsular opacities in 1 eye, mild and transient increase in lOP in 3 eyes, and chronic pigment dispersion in 2 eyes were observed. There was no serious complication.
?CONCLUSlON: Posterior chamber phakic intraocular lens implantation is an effective and safe method for correcting patients with extreme highly myopia.