1.Citation analysis of non-experimental nursing research papers
Chinese Journal of Practical Nursing 2010;26(29):73-75
Objective To describe the citations of non-experimentsl nursing research papers in China,to reflex the academic level of non-experimental nursing research papers and the utilization of reseachers to literature information. Methods 2547 non-experimental nursing research papers were manually searched out from 466 issues of two kinds of core nursing journals named Chinese Journal of Nursing and Journal of Practical Nursing (which was changed to Chinese Journal of Practical Nursing in 2003) from 1990 to 2006,bibliometric analysis was used to analyze their citations from quantities, price indicator, sorts, resources and languages. Results The quantity of citations per paper was 4.4, which increased over time; the Price indicator was 55.6%; citations to journal predominated(73.4%) and there was a growing trend over time; most citations were to medical journals outside the profession of nursing (59.1%), while citations to nursing increased gradually; Chinese (73.6%) was the language of most of the citations, while the percentage of English citations increased gradually. Conclusions The competence of absorbing information of researchers in China was gradually increasing, their competence of absorbing foreign information needs to be strengthened urgently.
2.Intraperitoneal transplantation of human umbilical cord mesenchymal stem cells in the treatment of acute liver injury in rats
Chinese Journal of Tissue Engineering Research 2013;(49):8527-8531
BACKGROUND:In vitro experiments have confirmed that human umbilical cord mesenchymal stem cells can be induced to differentiate into hepatocyte-like cells, thus which can be considered to function as liver repair.
OBJECTIVE:To observe the therapeutic effect of human umbilical cord mesenchymal stem celltransplantation on acute liver injuries in rats through in vivo animal experiments.
METHODS:Healthy Sprague-Dawley rats were randomly divided into three groups:normal control group without modeling, celltransplantation group, and PBS group. Rat models of acute liver injury were prepared by 10%CCl4-olive oil solution in the celltransplantation and PBS groups which were fol owed by intraperitoneal injection of 0.5 mL human umbilical cord mesenchymal stem cellsuspension and 0.5 mL PBS, respectively.
RESULTS AND CONCLUSION:Hematoxylin-eosin staining showed that pathological changes related to acute liver injury appeared at 24 hours after intraperitoneal injection of CCl 4 . Then, the liver structure recovered at 7 days after celltransplantation, but it did not recover til the 14th day after PBS injection. Compared with the normal control group, serum alanine aminotransferase and aspartate aminotransferase levels were significantly increased in the other two groups (P<0.05-0.01). In the celltransplantation group, the serum alanine aminotransferase and aspartate aminotransferase levels were significantly lower than those in the PBS group at 3 days after treatment (P<0.05-0.01), and recovered normal y after 7 days. cells positive for anti-human nucleoprotein antibody were found in the portal area of liver tissues in the celltransplantation group after 3 days of transplantation, and then cells positive for anti-human albumin antibody appeared after 7 days. These findings indicate that intraperitoneal transplantation of human umbilical cord mesenchymal stem cells can improve liver function and repair injured liver tissues after acute liver injury in rats to some extent.
3.Investigation of prevention of adhesion of post-operation of transcervical resecition of septa
Chinese Journal of Primary Medicine and Pharmacy 2008;15(6):938-940
ObJective To investigate the efficacy of different treatments applied to infertility patients with u-terine septa undergoing transcervical resection of septa to prevent the post-operation adhesion. Methods 55 infertili-ty patients with uterine septa underwent laparoscopy guidance transcervical resecition of septa(TCRS), different treatments were given to the patients post-operation, including placement of IUD in uterus cavity or not, artificial cy-cle treatment, GnRH-a medication using post-operation, hysteroscopy examination was performed for the first and third month post surgery and IUD was taken out in the third month post surgery. Results Total 54 eases completed hysteroscopy examination follow-up visits,of which 40 cases completed total two times of hysteroscopy in the first and third month, and 14 eases completed only once hysteroscopy examination. Whether or not placement of IUD hadno effect on uterus cavity shape(P > 0.05). Compared to eases without using artificial cycle treatment post-opera-tion, the endometrium was thicker in the cases with it post-operation. Both cases using and not using artificial cycle treatment were found to have endometrium covered in fundus under hysteroscopy in the third month post-operation.The satisfactory cavity shape was achieved on patient receiving GnRH-a medication. Conclusion Placement of IUD is not helpful in preventing the occurrence of post-operation adhesions. Individualized post-operation artificial cycle treatments should be applied to different patients and using GnRH-a medication should be in right direction. The hysteroscopy examination post-surgery should be given in time to prevent the new occurrence of adhesion in fundus post-operation.
4.Anticomplement effect of cord blood serum
Chinese Journal of Immunology 2001;0(10):-
Objective:To investigate anticomplement effect of cord blood serum.Methods:Based on the classical complement hamolytic assay,added serum in the reactions,then took the percentage of complement inhibited(Inhibition%) as the level of anticomplement effect of serum.Results:(1)Anticomplement activity in serum of cord blood(32.77?11.29)% was significantly higher than of maternal serum(15.07?4.66)%(P
5.Control of the Infection Source in the Preparation of Total Parenteral Nutrition Solution
China Pharmacy 2005;0(23):-
OBJECTIVE: To avoid the infection induced by the clinical application of total parenteral nutrition solution( TPN) . METHODS: The experience of quality control and etiological examination in the preparation and application of TPN for 62 patients in our hospital were analyzed retrospectively. RESULTS & CONCLUSION: The key to reduce the incidence of infection in the preparation and application of TPN is to keep the infection source under control.
6.METADATA EXPANDED SEMANTICALLY BASED RESOURCE SEARCH IN EDUCATION GRID
Journal of Pharmaceutical Analysis 2005;17(2):127-130
With the rapid increase of educational resources, how to search for necessary educational resource quickly is one of most important issues. Educational resources have the characters of distribution and heterogeneity, which are the same as the characters of Grid resources. Therefore, the technology of Grid resources search was adopted to implement the educational resources search. Motivated by the insufficiency of currently resources search methods based on metadata, a method of extracting semantic relations between words constituting metadata is proposed. We mainly focus on acquiring synonymy, hyponymy, hypernymy and parataxis relations. In our schema, we extract texts related to metadata that will be expanded from text spatial through text extraction templates. Next, metadata will be obtained through metadata extraction templates. Finally, we compute semantic similarity to eliminate false relations and construct a semantic expansion knowledge base. The proposed method in this paper has been applied on the education grid.
7.Effects of Electromyography-triggered Neuromuscular Stimulation on Motor Function of Stroke Patients
Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):71-73
Objective To study the effects of electromyography-triggered neuromuscular stimulation on upper extremity functional recovery of acute stroke patients. Methods 60 stroke patients who lost wrist extension even in the electromyography (EMG) within 4 weeks were randomly assigned to experimental group and control group. The experimental group received electromyography-triggered neuromuscular stimulation, and the control group received neuromuscular stimulation. They were assessed with EMG, Fugl-Meyer assessment (FMA), Barthel index (BI) before and 4 weeks after treatment. Results The EMG, scores of FMA and BI improved in all the patients after treatment (P=0.000), and improved more in the experimental group (P<0.05). Conclusion Electromyography-triggered neuromuscular stimulation can improve the motor function of hemiplegia, even in the patients without change of EMG.
8.Effect of antiepileptic drugs on the level of plasma homocysteine and asymmetric dimethyl arginine in epileptic patients
Jie XIA ; Zheng ZHENG ; Qimei ZHANG
Chongqing Medicine 2015;(6):783-784
Objective To investigate plasma homocysteine(Hcy)and asymmetric dimethyl arginine(ADMA)concentration in patients with epilepsy receiving oxcarbazepine(OXC)or sodium valproate(VPA)monotherapy.Methods Plasma were collected from 32 cases of OXC and 36 cases of VPA monotherapy.The levels of hcy and ADMA were detected and compared with healthy controls.Then the correlation of the levels and antiepileptic drug treatment duration was analyzed.Results The levels of hcy and ADMA in treatment groups were higher than in control gruops(P <0.05),and no difference between two treatment groups(P >0.05).Antiepileptic drug treatment duration and plasma Hcy,ADMA levels were positively correlated (r =0.274,P <0.05;r =0.256,P <0.05).Conclusion OXC and VPA elevated hcy and ADMA plasma levels in patients with epilepsy.Routine monitoring of plasma hcy and ADMA and supplementation of B vitamins and folate acid might have help to reduce thrombotic events occurring for patients receiving long-term OXC and VPA therapy.
9.Clinical characteristics and molecular genetics of Dent's disease: an update.
Chinese Journal of Pediatrics 2012;50(12):909-912
Animals
;
Child
;
Child, Preschool
;
Chloride Channels
;
genetics
;
Dent Disease
;
complications
;
diagnosis
;
genetics
;
therapy
;
Diuretics
;
therapeutic use
;
Humans
;
Hydrochlorothiazide
;
therapeutic use
;
Hypercalciuria
;
diagnosis
;
genetics
;
Mutation
;
genetics
;
Phosphoric Monoester Hydrolases
;
genetics
;
Proteinuria
;
diagnosis
;
etiology
;
genetics