1.Meta analysis of RCT for effectiveness and safety of fibrin glue versus suture in pterygium excision with conjunctival autograft
Wen, FAN ; Chang-zheng, CHEN ; Fei, LI ; Yi-qiao, XING
Chinese Journal of Experimental Ophthalmology 2011;29(12):1125-1129
Background Fibrin glue has been utilized to adhere the graft during the pterygium excision with conjunctival autografts.Several relevant clinical randomized controlled trial(RCT) and retrospective studies have been published abroad,but the samples for its effectiveness and safety issue of fibrin glue and suture are still underinvestigation.Objective Current study was to quantificationally assess the efficacy and safety of fibrin glue versus sutures in the application of pterygium excision with conjunctival autografts.Methods Based on established search strategy,a computerized literature search was conducted to identify all citations concerning the RCT for effectiveness and safety evaluation of fibrin glue and suture for the graft fixation during the pterygium excision with conjunctival autografts from MEDLINE ( from 2000 to October,2010 ),EMbase ( from 2000 to October,2010 ),Cochrane Central Register of Controlled Trials ( Issue 4,2010 ),CBMdisc ( 2000 to October 2010 ),CNKI ( 2000 to October 2010 ),and the relevant conference proceedings and references searched by hand was performed as supplement.The included literature was scored with Jadad table.The Cochrane Collaboration' s RevMan 5.0 software was used for the test of heterogeneity or test for overall effect.The effective indexes,such as operative duration,recurrence rate and complication,were evaluated by Meta analysis.Results Six RCTs involving 401 eyes of 377 participants were identified.These literatures were published with English in 2004-2010 from China,New Zealand,Sweden,Israel,Turkey and Malasia and the Jadad scores were 4-5.The quantitatively analysis revealed that fibrin glue appeared to short the operative time compared with suturing method (MD =14.23 ;95% CI:- 16.18- 12.29;P=0.00) and drop the rate of recurrence ( RR =0.49,95% CI:0.26 -0.95 ; P =0.03 ).No significant differences were found in the rate of postoperative graft dehiscence or absence (RR =3.41,95 % CI:0.85-13.68;P =0.08 ).Conclusions Fibrin glue shows the good effectiveness and easy application during the pterygium excision with conjunctival autografts.Long-term follow-up of multi-central RCTs with a larger number of cases are still needed to support this conclusion.
2.Application and Study of Simple and Manual Contrast Board in Double Contrast Examination
Xing WEN ; Yaka LIU ; Kunpeng ZHOU ; Yonglan ZHENG
Chinese Medical Equipment Journal 1989;0(04):-
Objective To study a simple and manual contrast board in Double Contrast Examination,so as to decrease labor intensity and the X-ray influence to the work staff.Methods The integrated design consisted of two parts:filled gas and oppressive container.The gas and Barium was injected into the large intestine by manual control and its volume may be adjusted casually according to the requirement.Results It is proved in clinical application that the design is reasonable,the structure is simple and the operation is convenient.Conclusion The device makes the relationship between medical staff and patients more harmonious.It worth popularizing.
3.Study of intermolecular interactions of piroxicam polymorphs
Wen-hui XING ; Cheng XING ; Hong-mei YU ; Zheng-yu FANG ; Li ZHANG ; Ning-bo GONG ; Yang LÜ
Acta Pharmaceutica Sinica 2022;57(7):2171-2176
Piroxicam has polymorphism. Different crystalline forms can exhibit different physicochemical properties and biological activities. Analysis of the intermolecular interactions is essential to reveal the formation mechanism and differences of polymorphs. In this paper, Hirshfeld surface analysis and semi-empirical methods were used to calculate and analyze the intermolecular interactions in seven polymorphic forms of piroxicam. The results show that the Hirshfeld surface analysis method can clearly and intuitively reveal the intermolecular interactions, among which H…H, O…H/H…O and N…H/H…N interactions account for 95% of the total energy. There are differences in the proportion and distribution of the forces of different crystal forms. The energy calculation shows that the lattice energy of the hydrate is significantly lower than that of the anhydrous forms, and in the specific energy distribution, the contribution of the dispersion force is the most prominent. Further interaction energy analysis was found that within the distance of 3.8 Å from the center of the piroxicam molecule, different crystalline forms of piroxicam molecule have different interaction energies with surrounding molecules.
5.Technical improvement in rapid sectioning of paraffin-embedded tissue blocks.
Xiao-ping ZHENG ; Wen-xing XU ; Li-kang LUO ; Yan-fei XU
Chinese Journal of Pathology 2009;38(1):57-58
Humans
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Leiomyoma
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pathology
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Microtomy
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methods
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Microwaves
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Paraffin Embedding
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methods
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Specimen Handling
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methods
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Thyroid Neoplasms
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pathology
8.Current research and development trend of swallowable biotelemetry systems.
Chinese Journal of Medical Instrumentation 2005;29(1):34-37
Swallowable biotelemetry systems are one kind of implantable biotelemetry systems. The research about swallowable biotelemetry systems is rapidly growing recently because they can be used to measure physiological and pathological parameters of human gastrointestinal tracts in vivo and they significantly improve patient comfort. This paper presents the current research of swallowable biotelemetry systems domestically and abroad. The development trend of these systems is analyzed at the end of the paper.
Capsules
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Electronics, Medical
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instrumentation
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Endoscopes, Gastrointestinal
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trends
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Equipment Design
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Gastrointestinal Tract
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physiology
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Humans
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Monitoring, Physiologic
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instrumentation
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methods
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Telemetry
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instrumentation
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methods
9.Surveillance of bacterial resistance from a hospital in Chongqing from 2004 to 2005
Chao ZHUO ; Bei JIA ; Wen-Xiang HUANG ; Xing-Ping ZHENG ; Chong-Zhi LI ;
Chinese Journal of Infection and Chemotherapy 2007;0(05):-
Objective To investigate the antimicrobial resistance of clinical isolates from a hospital in Chongqing during one year according to CHINET project.Methods Disc diffusion test (K-B method) was employed to study the antimicrobial resistance. WHONET5 was used for data analysis.Results In one year period from 2004 to 2005,690 non-duplicate isolates were collect- ed.Enterobacter isolates showed the lowest resistance rate to imipenem and meropenem.About 37.5% of E.coli and 31.4% of K.pneumoniae isolates produced ESBLs,respectively.All ESBLs-producing strains were susceptible to imipenem and mer- openem.About 37.2%,39.4% and 48.9% of P.aeruginosa isolates were resistant to imipenem,meropenem and ceftazidime, respectively.Pandrug-resistant (PDR) P.aeruginosa was isolated from our hospital.All strains of A.baumannii were sus- ceptible to imipenem and meropenem.About 37.7% of A.baumannii were resistant to cefoperazone-sulbactam.Twenty-nine strains showed the same resistant pattern among non-susceptible strains of A.baumannii,mainly derived from 2 clones by PFGE analysis.Conclusions The surveillance results suggest that prevalent strain resistant to cefoperazone-sulbactam may pres- ent in some ICUs.Resistance rate to cefoperazone-sulbactam increased significantly.
10.Research advances in the brain mechanisms of acupuncture effects based on the BOLD-fMRI technology
Yan SUN ; Chong-Bing MA ; An-Guo LIU ; Xing-Ke YAN ; Jing JIA ; Wen ZHENG
Journal of Acupuncture and Tuina Science 2020;18(6):474-480
By summarizing the recent literatures on brain mechanisms with acupuncture intervention based on blood oxygenation level-dependent (BOLD)-functional magnetic resonance imaging (fMRI), the BOLD-fMRI examination and analysis methods, the points to be acupunctured, the corresponding meridian activation regions, the specific intensity range, functions and indications of the acupoints, the manifestation of 'bi-directional regulation' characteristics, fMRI performance of chronergy, laterality and needling qi of acupuncture were reviewed to provide the ideas for future research in this area.