2.Effect of baicalin on inflammatory factors and oxygen free radical metabolism in patients with traumatic shock
Junda LIU ; Zhen LAI ; Kewei ZHENG
Chinese Journal of Primary Medicine and Pharmacy 2014;21(11):1617-1618
Objective To investigate the effect of baicalin on inflammatory factors and oxygen free radical metabolism in patients with traumatic shock.Methods 38 patients with traumatic shock were treated with baicalin 200mg intravenous injection when admitted to hospital.Before and 1 h after treatment,TNF-α,IL-6,IL-8,MDA and SOD were measured in blood.Results Compared with before treatment,TNF-,IL-6,IL-8,and MDA levels were decreased after treatment (t =7.32,6.12,20.21,16.10,all P < 0.05),while SOD activity was significantly increased (t =1.69,P < 0.01).Conclusion Baicalin could inhibit the production and release of inflammatory factors TNF-α,IL-6,IL-8 in patients with traumatic shock,reduce the damage of oxygen free radicals to the cells.Early treatment with baicalin had protective effect on patients with traumatic shock.
3.Behavioral disposition of nurses in emergency room and influential factors
Xiaorong LAI ; Wen ZHENG ; Haiyan YANG
Modern Clinical Nursing 2014;(1):1-4
Objective To investigate behavioral disposition of nurses in emergency room and analyze influential factors.Methods A total of 200 nurses from the emergency room participated in the survey using demographic questionnaire and the nursing behavior questionnaire.Results The total average score of the nursing behavior was(3.13±0.54),and the influential factors included the level of hospital,the time span for the job and the continued education on the infectious diseases(all P<0.01).Conclusions The nursing behaviors was at the medium level.The nursing administrators should provide the nurses with personal protection apparatus,strengthen education on infectious diseases and use incentive mechanism so as to improve the ER nurses' nursing behavior.
4.Diagnosis of Multi-slice Spiral CT Enhanced Scanning in Borderline and Invasive Ovarian Tumor
Shilei ZHENG ; Shusheng LAI ; Xianglin ZHANG
Chinese Journal of Medical Imaging 2017;25(6):465-469
Purpose To investigate the diagnostic value of multi-slice spiral CT (MSCT) enhanced scanning in borderline and invasive ovarian tumor,and to provide valuable image evidence for clinical treatment.Materials and Methods One hundred and one patients with pathological-confirmed borderline and invasive ovarian tumor in the First Affiliated Hospital of Jinzhou Medical University from October 2012 to October 2016 were selected,and the preoperative abdominal MSCT enhanced imaging,clinical and pathological data were retrospectively analyzed.The MSCT imaging was observed,and the prediction model of MSCT differentiating borderline and invasive ovarian tumor was established.Results The differences of onset age,menopausal status,tumor solid components,maximum diameter,septa and margin were all statistically significant between borderline and invasive ovarian tumor groups (P<0.05).The prediction model of MSCT differentiating borderline and invasive ovarian tumor was established using multivariate Logistic regression,on the basis of following variables (OR>l,P<0.05):tumor size,solid components and septa.The sensitivity and specificity of the prediction model were respectively 81.3% (95% CI:0.622-1.000) and 85.7% (95% CI:0.741-0.973) in predicting borderline ovarian tumor for patients before menopause,and respectively 92.1% (95% CI:0.835-1.000) and 91.7% (95% CI:0.761-1.000) for those after menopause.Conclusion MSCT enhanced scanning is helpful to differential diagnose of borderline and invasive ovarian tumor,and it has important significance for clinical treatment and prognosis evaluation.
5.Mini Percutaneous Nephrolithotripsy for Non-nephredema Renal Calculi
Qiang XIA ; Jiansheng LAI ; Dongsheng ZHENG
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To study the effect of mini percutaneous nephrolithotripsy (MPCNL) for non-nephredema kidney calculi. Methods A total of 47 patients with non-nephredema kidney calculi were enrolled in this study. Physiological saline solution was infused into the kidney through a ureteral catheter to induce hydronephrosis. C-arm X-ray machine was employed in percutaneous puncture and Wolf EMS was used to smash the calculi. Results The mean operation time was (120?35) min.The calculi were removed through one passage in 38 cases,through two passages in 6, and three passages in 3. Among the 47 patients, the MPCNL was performed once in 35, and twice in 12. The stone-free rate was 83.0% (39/47) and final stone-free rate was 93.6% (44/47). No complications were noted in all the patients. Conclusions Highly skilled technique is necessary in MPCNL for non-nephredema kidney calculi. The MPCNL is a safe, minimally invasive, and effective method. By using MPCNL, patients have less trauma, lower rate of calculi remaining, and quick recovery. As long as the surgeons are familiar with the technique of MPCNL and the anatomy of non-nephredema kidney, the therapeutic outcome can be as good as that in the patients with nephredema renal calculi.
6.Diagnosis and treatment of intestinal obstruction by foodballs in children(21 cases report)
Zhi-Hong LAI ; Yan-Jun ZHENG ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To explore diagnosisand treatment of intestinal obstruction by foodballs in children. Methods The clinical datum of 21 cases of intestinal obstruction by foodballs in children were retrospectively ana- lyzed.Results While admission,only 2 cases could provide the history of having eaten foodballs wholly which could not be digested easily.The characteristics of clinical manifestation were intestinal obstruction completely or incom- pletely.All 21 cases had been treated conservatively first,only one case was successful and the other 20 cases had been cured by surgery afterwords.Conclusion There is no specific feature in clinical manifestations of intestinal ob- struction by foodballs in children,so it is difficult to make the diagnosis,but it must be considered suspicious especial- ly for those from rural area and with simple intestinal obstruction with reasons not known yet.If conservative therapy is failure in a short period,an operation should be done immediately.During operation,it is necessary to examine the whole digestive system thoroughly.
7.Effect of mild hypothermia on the opening of tight junction of cerebral endothelial cells following traumatic brain injury
Runlong LAI ; Dexiang ZHOU ; Fengren ZHENG
Chinese Journal of Trauma 1993;0(05):-
Objective To observe the effect of early mild hypothermia on the opening of tight junction of cerebral endothelial cells following traumatic brain injury in order to illustrate possible mechanism of low permeability of blood brain barrier (BBB) treated by mild hypothermia. Methods A total of 90 Wistar rats were randomly divided into normothermia control group (n=10),normothermia injury group (n=40) and mild hypothermia group (n=40). The opening state and its extent of tight junction were observed using lanthanum trace labeling with electron microscope. At the same time,water content of cerebral tissue at different phases in normothermia injury group and mild hypothermia group was measured by means of dry-wet weight and analyzed statistically. Results The tight junction was under preliminary opening three hours after trauma and reached the maximum opening within 24-48 hours after trauma,lasting for 72 hours in the normothermia injury group. However,slight opening appeared only in the mild hypothermia group. Water content of cerebral tissue in the mild hypothermia group lessened obviously in contrast to that in the normothermia injury group,with significant difference 3,24 and 72 hours after trauma ( P
8.A Study on Apoptosis and Expression of Fas, bax and bcl-2 Proteins in Testicular Carcinoma
Xiangan TU ; Tang LAI ; Keli ZHENG
Journal of Chinese Physician 2001;0(01):-
Objective To explore the role of apoptosis and Fas, bax and bcl-2 proteins in the pathogenesis of testicular carcinoma. Methods Cell apoptosis was determined with TUNEL and flow cytometry, and the expression of Fas, bax and bcl-2 proteins were detected by cellular immunofluoresence technique in 56 cases of testicular carcinomas. Results Apoptotic index was closely correlated with the pathological type and lymph node metastasis of testicular carcinomas(P0.05). The apoptotic index was positively correlated with Fas and bax expression, and negatively correlated with bcl-2 expression (P
9.Analysis of the casualties aboard warships attacked by anti-ship missiles
Haoyang SHAN ; Xinan LAI ; Ran ZHENG
Military Medical Sciences 2017;41(3):218-221
In the future,anti-ship missiles(ASM) will be major weapons in the sea war.It is very important to handle the profile of the casualties aboard warships attacked by ASM for development of naval health service.The statistical result shows there is a greater chance of casualties but less chance of warships being sunken by ASM.Besides,medical staffs should pay more attention to the first aid for victims due to blast,burn,smoke inhalation and penetration while the danger of the sea water immersion should not be ignored.
10.Revision of collectivism and individualism scale and study on the development of middle school students' value
Feng LIU ; Jianwei LAI ; Gang ZHENG
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(6):568-571
Objective To explore the construct validity of collectivism and individualism scale( COLINDEX) and the reliability and construct validity of its Chinese revision;and to study the development of middle school students' value. Methods The revised scale was used and 5875 middle school students were tested. Resuits Two-factor model of COLENDEX was not substantiated by data,while three factors were abstracted by EFA and confirmed subsequently by CFA. Four factors were abstracted from the Chinese revision of COLINDEX, and four-factor model was confirmed. The Cronbach's alpha coefficients of the total scale (0.90) and four sub-scales (0.84,0.76,0.84 and 0.74 )were all significantly high. MANOVA was performed to detect gender and grade differences of means in the four dimensions of the revised scale. The main effects of gender and grade reached the significant level; however, interaction between them did not. Conclusion Collectivism and individualism, two dimensions of Chinese middle school students' value, were not mutually independent. The revised version of COLINDEX was qualified to be used in further research. The grades on collectivistic items of middle school students were higher than those on individualistic items.