2.Research of radiation dose rate around patients underwent renal dynamic imaging of SPECT with 99Tcm-DTPA
Zuowei ZOU ; Jianhua GENG ; Rong ZHENG
China Medical Equipment 2017;14(9):23-26
Objective:To study the radiation dose rate around patients underwent renal dynamic imaging of SPECT with 99Tcm-DTPA, so as to provide the basis for ensuring the radiation safety of the surrounding environment and the general public.Methods: 109 patients who underwent renal dynamic imaging were enrolled in this study, and the radiation dose rates of different time and different distance after 99Tcm-DTPA was injected patients were measured. And then, the changes of dose rate following time and distance were analyzed. Results: At the 0.5h, 1h, 2h, 3h, 6h, and 7h after radiopharmaceuticals were injected patients underwent renal dynamic imaging, the radiation dose rates were 0.76-8.86 μSv/h, 0.68-7.27 μSv/h, 0.57-4.52 μSv/h, 0.56-3.90 μSv/h, 0.23-2.07 μSv/h and 0.21-1.05 μSv/h, respectively, between 0.5 m and 4 m away from patients. At 24h after radiopharmaceuticals were injected, all of radiation dose rates at different distances around patients were same with background values.Conclusion: The radiation dose rates around patients underwent renal dynamic imaging will rapidly decrease with the increasing of time and distance. At 24h after radiopharmaceuticals were injected, all of radiation dose rates at different distances away from patients were same with background values.
3.Research and Practice on the Teaching Model of Physiology for Students of College Training to Achieve University Degree in the PLA
Peisen PAN ; Jinxia GENG ; Dawei ZHENG
Chinese Journal of Medical Education Research 2003;0(02):-
A questionnaire was taken in regard to the basic situation and study requirement for students of college training who want to get a university degree in the PLA.Some practical improvement was made and a preliminary model of physiological teaching for such students was established
4.Analysis of the diagnosis and treatment of acute steroid-resistant rejection after liver transplantation
Tian SHEN ; Lei GENG ; Shusen ZHENG
Chinese Journal of Hepatobiliary Surgery 2013;19(11):877-880
The main feature of acute steroid-resistant rejection (ASRR) after liver transplantation is a lack of response to steroids.Although some effective immunosuppressants are available,there is no uniform treatment presently available.This paper will focus on exploring the mechanism of ASRR and formulating individually approached strategies.
5.Application of subaxillary curved mini-incision thoracotomy in thoracic operations
Xiaozhong GE ; Heping ZHENG ; Zhongwei GENG
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To investigate the clinical application of subaxillary curved mini-incision thoracotomy in thoracic operations. Methods Through a subaxillary curved mini-incision between the latissimus dorsi muscle and the serratus anterior muscle (length of incision, 8~14 cm), thoracic operations were performed in 65 patients with thoracic diseases, including pneumothorax or hemopneumothorax (13 patients), pulmonary benign tumor (23 patients), mediastinal tumor (4 patients), and esophageal benign or malignant tumor and cardiac cancer (25 patients). Results All the patients were successfully operated on. No surgery-related deaths occurred. The incidence of complications was 6.2% (4/65), including pleural effusion in 1 patient, pulmonary infection in 2 patients, and anastomotic leakage of esophagogastrostomy in 1 patient.Conclusions Subaxillary curved mini- incision thoracotomy, characterized by minimal invasion, little blood loss, mild influence on cardiopulmonary functions, quick recovery, and good cosmetic outcomes, is an ideal option for the treatment of thoracic diseases.
6.Problems in Community-based Rehabilitation during the Period of 12th Five-year Plan in China
Lei ZHENG ; Lin GENG ; Xinjian ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2015;21(3):365-366
The development of community-based rehabilitation (CBR) needs to improve to meet the change of environment during the period of 12th Five-year Plan. The problems of CBR development included 3 major contradictions: administration of CBR and marketization of medical services; professionals demand of CBR and their professional development; and the demand of CBR and capacity of services. It is necessary to establish some market-oriented CBR project, pay attention to professional development, and promote the capacity of the community rehabilitation agencies.
7.Discussion about the sampling positions of the bag-type infusion sets for single use in the ethylene oxide residues detection.
Xing LIU ; Dixin ZHENG ; Yuanyuan GENG ; Zheng CHEN
Chinese Journal of Medical Instrumentation 2014;38(1):68-70
This paper selects the bag-type infusion sets for single use as samples, which are produced by different manufacturers and based on the ethylene oxide sterilization. The ethylene oxide sterilization residues in different parts of samples are detected by colorimetric analysis. Combined the comparison of the ethylene oxide residues testing results in the different parts of the same sample with the actual situation in clinical use, more reasonable sampling positions are found to detect the ethylene oxide sterilization residues. The result of this experiment will play a guiding role in the detection of the actual samples.
Disposable Equipment
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Equipment Contamination
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prevention & control
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Ethylene Oxide
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analysis
8.Mechanism and prevention of the formation of hypercoagulable state in patients with malignant tumor
Guangming ZHANG ; Zheng WANG ; Xuewei ZHANG ; Ping GENG
Journal of International Oncology 2015;(6):445-447
The majority of patients with malignant tumors have hypercoagulable state,which easily leads to thrombosis,and is closely related with recurrence of tumor metastasis.The formation mechanism of hypercoagulable state is related to tumor,tumor treatment,complications etc.The main diagnostic indicators are the platelet,cruor and fibrinolysis,P-selectin and lysosomal protein,blood rheology.Tumor patients with the high risk of thrombus should use low molecular weight heparin.Thromboembolism should be prevented in bedridden patients with tumor and tumor associated operation.Tumor patients with venous thromboembolism should be given thrombolytic treatment.Tumor patients with hypercoagulable state should be treated by antico-agulant therapy combined with chemotherapy.
9.Construction and identification of recombinant adenovirus vector of human neuropilin-1 gene
Jianbao ZHENG ; Zhimin GENG ; Qiang CHEN ; Lin WANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2014;(3):415-418
Objective To construct a adenovirus vector containing human NRP-1 gene and 3Flag gene to interaction between tumor and interstitial cell.Methods Plasmid containing NRP-1 gene was digested by AgeⅠand NheⅠ restriction endonuclease.Then the DNA was ligated into linearized pDC315-3Flag vector.After having been constructed,the pDC3 1 5-NRP-1-3 Flag plasmid was co-transfected with framework plasmid pBHGlox△E1 , 3Cre into HEK 293 cells to obtain the homologous recombinant adenovirus,which was then amplified and purified its titer tested.Expression of NRP-1 protein was detected using Western blot.Results Polymerase chain reaction and sequencing analysis confirmed that the shuttle plasmid pDC3 1 5-NRP-1-3 Flag and design were consistent. Cytopathic effect was observed by inverted phase contrast after transfecting HEK2 9 3 cells with shuttle plasmid pDC315-NRP-1-3Flag.95-130 ku was detected by Western lot after transfecting HEK293 cells with shuttle plasmid pDC315-NRP-1-3Flag and recombinant adenovirus,the size being consistent with the NRP-1-3Flag fusion protein (104 ku),with a titer of 2.00E+11PFU/mL.Conclusion The recombinant adenovirus vector for human NRP-1 gene was successfully constructed expressed in HEK 2 9 3 cells.
10.Exploring the new strategy of training and education for hepatobiliary robotic surgeons
Geng CHEN ; Zhanyu YANG ; Shuguo ZHENG ; Ping BIE
Chinese Journal of Medical Education Research 2012;11(4):391-393
Robotic surgery is a major trend of mini-invasive surgery,which is still in its infancy in China.The training and education of robotic surgeons is a problem to be solved imperatively.In our clinical practice,we explored the new strategy of training and education for hepatobiliary robotic surgeons by assimilating the essence of traditional surgery education and by drawing lessons from the successful training of robotic surgery in foreign countries.Satisfactory teaching effect was obtaincd.