OBJECTIVE:To study the effect of Kanglaite combined with chemical therapy on advanced non-small cell lung cancer.METHODS:70 patients were randomly divided into treatment group and control group(n=35).Both groups were given GP regime of chemical therapy.Treatment group were additionally treated with Kanglaite.Clinical efficacy,quality of life and adverse reactions of 2 groups were observed.RESULTS:Recent response rate were 54.29% for treatment group and 37.14% for control group,there were statistical significance in difference between 2 groups(P