Objective To explore particularity of the diagnosis and treatment with massive bilateral chronic subdural hematoma (BCSDH) in elders.Method The clinical data of 25 elders with BCSDH treated in our hospital from 2007 to 2011 were analyzed retrospectively.All patients were examined with computerized tomography (CT) of 25 patients through the bilateral trephined hole.Results Twenty-four patients recovered better,the symptom significantly improved.After operative 1 month,14 patients? hematoma disappear,6 patents only had little bilateral subdural effusion,4 patents only had little unilateral subdural effusion.One patient appeared massive subdural effusion on the second day after operation,the familiality gave up therapy,and the patient was dead.Conclusion CT scanning should be taken before you make correct diagnisis.Bilateral single twist-drill craniostomy with irrigation and drainage is a chief method to massive BCSDH.

Objective To observe the effects of systematic mental intervention, with combined centralized teaching, group interview and individual consulting, on mental health, personality and coping style in recruits, and explore an optimal intervention model for recruits' mental health. Methods Two thousand and sixteen recruits in one unit were involved in the present study, among them 1064 were allocated to study group, and the remaining 952 to control group. Recruits in study group received centralized teaching with battalion as a unit, and received group interview in squad or platoon as a unit, and meanwhile individual interview was conducted. Symptoms Checklist-90 (SCL-90), Eysenck Personality Questionnaire (EPQ) and Simplified Coping Style Questionnaire (SCSQ) were filled one month after they were enlisted in the army and 3 days before the training ended. Recruits in control group undertook the same tests mentioned above only 3 days before the training ended. Results The total score and factor scores except hostility in SCL-90 test were significantly lower after than before systematic mental intervention (P<0.05), the hostility score was slightly higher than before intervention but with no statistical significance (P>0.05). The total score and factor scores except paranoia in SCL-90 test were significantly lower in study group than in control group after intervention (P<0.05). Scores of extraversion-introversion tendency and nervousness were significantly lower after than before intervention (P<0.001), the scores of psychoticism and social lie were slightly higher but with no statistical significance (P>0.05), the score of active coping was significantly higher (P<0.001), and of negative coping was significantly lower (P<0.001) after than before intervention. The ratio of the score over 2 and above declined obviously (P<0.05) in neurosis, SCL-90 abnormality, SCL-90 total scores, number of positive items, somatization, obsession, interpersonal sensitivity, depression, anxiety, hostility, phobia, paranoid, and psychotic factor after than before intervention in recruits. Conclusion Systematic mental intervention, which consisted of combined centralized teaching, group interview and individual consulting, may promote the mental health, personality and coping style in recruits.

Humans ; Rectal Fistula ; surgery ; therapy

Objective To explore inhibitory effects of ginsenoside on the proliferation of human thyroid canc-er SW579 cells in vitro and expression of C -myc and Bcl -2 protein.Methods Human thyroid cancer SW579 cells were cultured according to conventional method.The study was divided into the control group and ginsenoside group (20,40,8ug/mL).Inhibitory role of ginsenoside on proliferation of SW579 cells was detected by MTT assay.Western-blot method was used to determine expression levels of C -myc and Bcl -2 protein in different group.Results The inhibition rates of 20,40,80μg/mL ginsenoside to SW579 thyroid carcinoma cell were 22.35%,51.76% and 68.24% respectively.Which meaned ginsenoside had obvious inhibitory effect compared with the control group(P <0.01),and inhibition increased with the increase of solubility(P <0.01).C -myc and Bcl -2 protein were reduced progressively in place with the increase of ginsenoside concentration by Western -Blot analysis (P <0.01 ).Conclusion Gisenoside may play the inhibitory role on proliferation of human thyroid cancer SW579 cells in vitro, and its mechanism may be related with down -regulation of C -myc and Bcl -2 protein.

Objective To observe inhibitory effects of Ginsenoside on the proliferation cultured stem cells of human rectal carcinoma in vitro.Methods Tumor stem cells of rectal carcinoma in human were cultured in vitro and divided into saline water group,reltitrexed group(3mg/mL),and Ginsenoside(25μg/mL)plus reltitrexed(3mg/mL) group,with dosage of qd and for 2 weeks.Cells growth was observed under the microscope,and immunofluorescence staining was used to detect CD +133 expression of rectal carcinoma cells.MTT colorimetric method was taken to measure inhibitory of Ginsenoside on proliferation of tumor stem cells of rectal carcinoma.Apoptosis of tumor stem cells of rec-tal carcinoma lead by Ginsenoside was observed by DAPI staining.Results Part of cells were growing up like ball and CD +133 immunofluorescence staining was positive.Inhibitory role of Ginsenoside plus reltitrexed on CD +133 cells of rectal carcinoma appeared on the first day,which was bigger than that of retitrexed by MTT method (P =0.03).Com-pared with the retitrexed group,Gisenoside combined with reltitrexed reduced CD +133 cells expression of rectal carcino-ma,in which optical density and area density of CD +133 cells were obviously decreased with statistical significance (P =0.007,P =0.006,respectively).Conclusion Gisenoside plays the remarkably inhibitory role on proliferation of CD +133 cells of rectal carcinoma.

0.2).The lymphocyte counts of the KD area grain group and the group of the KD area grain supplemented with Se were lower than that of the non-KD area grain group, and the CIC level and the hepatic Se content were much lower in the group of the KD area grain than in the other groups (p

To observe the application effect of anti-eyebrow small incision cataract extraction combined with lOL implantation in blindness prevention and treatment
●METHODS: A total of 526 cataract patients included in regaining sight project of China Disabled Persons' Federation were underwent anti - eyebrow small incision cataract extraction combined with lOL implantation from May 2010 to August 2013.
●RESULTS: Postoperative 1d, uncorrected visual acuity >0. 3 were 345 cases (65. 6%), 0. 1 - 0. 3 were 152 cases (28. 9%), <0. 1 were 29 cases (5. 5%); 1wk after surgery:>0. 5 were 395 cases (75. 1%), 0. 3 - 0. 4 were 101 cases (19. 2%), < 0. 3 were 30 cases (5. 7%). Visual recovery rate was 100%, residual rate was 92. 5%. lntraoperative, 16 cases occurred posterior capsular rupture, 3 cases iridodialysis, 2 cases were Descemet's membrane avulsion. Postoperative, 56 cases ocurred corneal edema, 10 cases of central cornea stroma edema, 22 cases of secondary high intraocular pressure, were restored to normal bansis on the corresponding treatments.
●CONCLUSlON: Anti - eyebrow small incision cataract extractio combined with lOL implantation is effective, and has low complication rate, high security, can popularization and application in large - scale sight rehabilitating project.

OBJECTIVE:To investigate the role of clinical pharmacists in the therapy for patient with pulmonary aspergillosis complicated with rhabdomyolysis(RM). METHODS:Clinical pharmacists participated in the therapy for RM patients with pulmo-nary aspergillosis,and assisted physicians to optimize and improve therapy plan from RM therapy,anti-infection and liver protec-tion:stop taking Bicyclol tablet,continue Micafungin for injection 50 mg,ivgtt,qd for anti-infection;suspend liver-protective drug Compound glycyrrhizin;closely monitor therapeutic efficacy and ADR. RESULTS:Physicians adopted the suggestions of clini-cal pharmacists,and the situation of RM were improved. The patient were discharged from hospital 24 d later. CONCLUSIONS:Clinical pharmacists participate in therapy for RM patient with pulmonary aspergillosis and assist physicians to improve therapy plan,which contribute to rational drug use and the safety of drug use.

The in-stent restenosis is one of the main complications in coronary artherosclerotic heart disease patients after PTCA and PCI.How to prevent it remains one of the most important projects in intervention therapy.In this paper,the preventive role of intravenous ultrasound and drug eluting stent were reviewed.

Objective To observe the effect of cupping plus Chinese medicinal fumigation on expectoration in patients with chronic obstructive pulmonary disease (COPD) due to phlegm-heat obstructing the lung. Method Eighty-two patients with COPD due to phlegm-heat obstructing the lung were randomized into a treatment group and a control group, 41 cases in each group. The control group was given regular Western medications, while the treatment group was intervened by cupping plus Chinese medicinal fumigation in addition to the treatment given to the control group, once a day, 5 d as a treatment course. The therapeutic efficacies were observed after 2 treatment courses. Result The clinical effective rate of the treatment group was higher than that of the control group, with a statistical significance (P<0.05). Conclusion Cupping plus Chinese medicinal fumigation can enhance the expectoration in patients with COPD due to phlegm-heat obstructing the lung.