2.Comprative study of percutaneous kyphoplasty by balloon dilatation between unipedicular and bilateral pedicle approach for the treatment of osteoporotic vertebral compression fractures
Haoyu WANG ; Ming HUANG ; Mingjie GAO ; Lei FEI ; Zhen FANG
The Journal of Practical Medicine 2015;(20):3317-3320
Objective To compare the clinical efficacy of percutaneous kyphoplasty (PKP) by balloon dilatation between unipedicular and bilateral pedicle approach for the treatment of osteoporotic vertebral compression fractures (OVCF). Methods From January 2012 to March 2014, 56 patients with single-level or double- level OVCF were randomly divided into two groups. 29 patients with 33 vertebral bodies were performed by PKP through unipedicular approach and 27 patients with 31 vertebral bodies through bipedicular approach , used PMMA bone cement filling vertebral. The clinical data of patients were prospectively analyzed and the clinical efficacy was compared between two groups. Results The VAS scores, Beck value, Cobb angle and ODI scores after operation improved in both groups (P < 0.01),but there were no significant difference between two groups(P > 0.05). The operative time, X-ray exposure time and volume of bone cement in unilateral group were less than that of bilateral group(P < 0.01). There were no significant difference in the incidence of bone cement leakage ,the pain relief and the incidence of complications between two groups (P > 0.05). Conclusion Both unipedicular and biopedicular PKP are significant improvement for the OVCF, vertebral strengthen showed similar efficacy, but the former has easy operation procedure, can shorten operative time and reduce X-ray exposure time and less volume of bone cement.
3.Temperature Sensation Threshold of Trunk Skin in Healthy Adults
Hui-li ZHANG ; Ming-ming GAO ; Hua-zhen GUO ; Gui-yun SONG ; Pu ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2015;21(7):804-806
Objective To measure the temperature sensation threshold of trunk skin in healthy adults. Methods The threshold of cold sensation, warm sensation, cold pain sensation and heat pain sensation of trunk skin key points (T3, T7 and T11) were measured with Thermal Sensory Analyzer in 123 healthy adults. Results The thresholds of cold, warm, cold pain and heat pain sensations were obtained. The standard deviation of cold and warm threshold was less than that of heat pain. The range of cold sensation threshold was the largest. The heat pain sensation threshold increased with segmental declining and the sensation threshold increased with age. Conclusion Normal reference value should be established variously with the segment and age. The threshold of cold, warm varies less, while the threshold of cold pain and heat pain varies too much.
4.Study of effects of complex aerobatics on serum insulin, cortisol and angiotensin II.
Ming Gao LI ; She Zhen QIN ; Gui Xi MA ; Lang En XU ; Xin Hua ZHANG
Korean Journal of Aerospace and Environmental Medicine 1993;3(1):112-118
No abstract available.
Angiotensin II*
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Angiotensins*
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Hydrocortisone*
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Insulin*
5.Influence of complex aerobatics on serum gastrin level of pilots.
Gui Xi MA ; She Zhen QIN ; Ming Gao LI ; Lan Gen XU ; Xin Hua CHANG
Korean Journal of Aerospace and Environmental Medicine 1993;3(2):71-72
No abstract available.
Gastrins*
6.Surgical treatment strategy for flatfoot related with accessory navicular.
Yin-shuan DENG ; Qiu-ming GAO ; Ping ZHEN ; Kang-lai TANG
China Journal of Orthopaedics and Traumatology 2015;28(2):188-194
Accessory navicular source flatfoot is one of the foot deformity of clinical common disease,its treatment method is more controversial, differences in clinical efficacy of different surgical methods, according to accessory navicular source flatfoot symptoms of surgical treatment,there is no uniform standard, around a pair of accessory navicular excision how to reconstruct the arch produced a series of operation methods, the clinical curative effect of different operative methods produce also different, how to develop the operation strategy, choose operation method, and after acessory navicular excision whether to rebuild posterior tibial tendon, how to rebuild, the problems such as how to rebuild is the research hotspot and difficulty, looking forward to further research.
Flatfoot
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diagnosis
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surgery
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Foot Diseases
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surgery
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Humans
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Reconstructive Surgical Procedures
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methods
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Tarsal Bones
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abnormalities
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surgery
7.Current status and prospect of translational medicine in nanotechnology.
Guang-yu GAO ; Mei-ling CHEN ; Ming-yuan LI ; Zhen-bo YANG ; Zhi-ping LI ; Xing-guo MEI
Acta Pharmaceutica Sinica 2015;50(8):919-924
Nowadays, nanotechnologies have shown wide application foreground in the biomedical field of medicine laboratory tests, drug delivery, gene therapy and bioremediation. However, in recent years, nanomaterials have been labeled poisonous, because of the disputes and misunderstandings of mainstream views on their safety. Besides, for the barriers of technical issues in preparation like: (1) low efficacy (poor PK & PD and low drug loading), (2) high cost (irreproducibility and difficulty in scale up), little of that research has been successfully translated into commercial products. Currently, along with the new theory of "physical damage is the origin of nanotoxicity", biodegradability and biocompatibility of nanomaterials are listed as the basic principle of safe application of nanomaterials. Combining scientific design based on molecular level with precision control of process engineering will provide a new strategy to overcome the core technical challenges. New turning point of translational medicine in nanotechnology may emerge.
Biocompatible Materials
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Nanostructures
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toxicity
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Nanotechnology
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Translational Medical Research
8.Quantitative analysis of craniofacial skeleton asymmetry by three-dimensional computed tomography.
Rui-Chen WANG ; Gui-Zhen LI ; Chun-Ming LIU ; Chi-Yu JIA ; Quan-Wen GAO ; Yan HAN
Chinese Journal of Plastic Surgery 2013;29(6):435-439
OBJECTIVETo present a method of quantitative diagnosis of craniofacial skeleton deformities based on three-dimensional computed tomography (3D CT).
METHODS20 cases with facial asymmetric deformities underwent 3D CT and the 3D images were reconstructed by Mimics 10.0 (Belgium). Anatomical landmarks were located and the coordinate of the landmarks obtained. Axial images of 1 patient with Romberg disease was used as representative case. The differences in the distance between the right landmarks and the left were calculated and analyzed.
RESULTSThe measurement results were not significantly different between two stages with an interval of 4 weeks ( P > 0.05), showing a reproducible resutls. The deviation of landmarks at facial midline increased gradually from upward to downward, reaching (2.63 +/- 0.54) mm at menton point. Paired landmarks showed asymmetry in three dimensions, especially gonion point on the left side, which was deviated 10.21 mm inward, 9.26 mm forward, 6.30 mm upward, compared to the opposite side.
CONCLUSIONSThe method of 3D CT quantitative analysis can provide precise information in the diagnosis and treatment planning of facial asymmetry deformity.
Anatomic Landmarks ; diagnostic imaging ; Cephalometry ; Craniofacial Abnormalities ; diagnostic imaging ; Facial Asymmetry ; diagnostic imaging ; Humans ; Imaging, Three-Dimensional ; methods ; Tomography, X-Ray Computed ; methods
9.Effect of substrate of edible mushroom on continuously cropping obstacle of Rehmannia glutinosa.
Rui-Hong RU ; Xuan-Zhen LI ; Xiao-Shu HUNAG ; Feng GAO ; Jian-Ming WANG ; Ben-Yin LI ; Zhong-Yi ZHANG
China Journal of Chinese Materia Medica 2014;39(16):3036-3041
The continuous cultivation of Rehmannia glutinosa causes the accumulation of phenolic acids in soil. It is supposed to be the reason of the so called "continuously cropping obstacle". In this study, phenolic acids (hydroxybenzoic acid, vanillic acid, eugenol, vanillin and ferulic acid) were degraded by the extracta of all the tested spent mushroom substrate (SMS) and the maximal degradation rate was 75.3%, contributed by extraction of SMS of Pleurotus eryngii. Pot experiment indicated that hydroxybenzoic acid and vanillin in soil were also degraded effectively by SMS of P. eryngii. The employment of SMS enhanced ecophysiology index to near the normal levels, such as crown width, leaves number, leaf length, leaf width and height. At the same time, the fresh and dry weight and total catalpol concentration of tuberous root weight of R. glutinosa was increased to 2.70, 3.66, 2.25 times by employment of SMS, respectively. The increase of bacteria, fungi and actinomycetes numbers in rhizosphere soil were observed after the employment of SMS by microbial counts. The employment of SMS also enhanced the enzyme activity in soils, such as sucrase, cellulase, phosphalase, urease and catelase. These results indicated that the employment of SMS alleviated the continuously cropping obstacle of R. glutinosa in some extent.
Agaricales
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chemistry
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metabolism
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Agriculture
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methods
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Biodegradation, Environmental
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Hydroxybenzoates
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analysis
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metabolism
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Rehmannia
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growth & development
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metabolism
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Soil
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chemistry
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Soil Microbiology