Objective To explore the relationship between the protein expression of PCNA and biological behavior science in benignant pituita ry adenoma.Methods The protein expression of PCNA in 58 patien ts with pituitary adenoma were determined by ABC immunohistochemical method.Results The PCNA index was significantly higher in the patients with recurrent pituitary adenomas than in nonrecurrent ones(P<0.05).There was no significantly difference between bleeding and unbleeding group,cystic and noncystic group,large type and unlarge type group(P>0.05 respectively) .Conclusion The protein expressions of PCNA reflected the proli ferative activties of pituitary adenomas, and could be taken as one of the indic ators to evaluate recurrence and prognosis of the tumor.

Aged ; Apraxias ; physiopathology ; Gait Apraxia ; physiopathology ; Humans ; Parkinson Disease ; diagnosis ; physiopathology

Alzheimer Disease ; metabolism ; Animals ; Antioxidants ; metabolism ; Mice ; Polysaccharides ; pharmacology

Animals ; Curcumin ; pharmacology ; Diabetes Mellitus, Experimental ; drug therapy ; Rats

Animals ; Burns ; drug therapy ; metabolism ; physiopathology ; Drugs, Chinese Herbal ; pharmacology ; therapeutic use ; Female ; Male ; Mesentery ; blood supply ; Microvessels ; drug effects ; physiopathology ; Phytotherapy ; Rats ; Rats, Sprague-Dawley ; Superoxide Dismutase ; metabolism ; Trillium ; chemistry

Objective:To analyze neuropsychological characteristics of a Chinese patient with semantic dementia (SD)。Methods:A patient with SD was selected to finish 11 neuropsychological tests and MRI and XeCT。Results:(1)Selective impairment of semantic memory caused severe anomia, impaired spoken and written single-word comprehension, reduced generation of exemplars on category fluency tests and an impoverished fund of general knowledge; (2)relative sparing of other components of language output and comprehension; normal perceptual skill and non-verbal problem-solving abilities; relatively preserved episodic memory; (3)a reading disorder with pattern of surface dyslexia;(4) radiological investigations (MRI and XeCT) have shown severe left temporal neocortex atrophy.Conclusion:There are similar clinical and neuropsychological characteristics for SD between the Chinese patient and the sample of Western. Selective impairment of semantic memory may bring about by left temporal neocortex atrophy。

The G395R mutation of human sodium/iodide symporter gene was investigated by PCR-RFLP in 52 children with congenital hypothyroidism and 106 health children. The result suggested that G395R mutation may not be the main cause of congenital hypothyroidism in Qingdao.

Objective: To develop a grinding intrument for removing the remaining bonding material and polishing the dental enamel after orthodontic treatment. Methods: A dental griding instrument was made based on ultrasonic principle with the frequency of 25～45 kHz. 60 premolars extracted for orthodontic purpose were used in the experiment, before treatment the surface roughness was measured and recorded as Ra 1. Brackets were adhered to the premolars, and then debonded. The surface enamel of 30 teeth were polished by the ultrasonic grinding instrument (group of GI), that of another 30 by conventional technique(group of CT) , the roughness was measured and recorded as Ra 2. Results: In group GI Ra 1 and Ra 2 were 0.846 6?0.428 2 and 0.740 5?0.372 1(P0.05), respectively. After treatment Ra 2 in group GI was smaller than that in group CT(P

OBJECTIVE:To study the antithrombotic effect of orientoside.METHODS:The effects of prophylactic oriento_side on the clotting time in vitro and the systemic clots dissolution of mice,the plasma prothrombin time(PT),the kaolin partial thromboplastin time(KPTT),the thrombin time(TT),and the platelet aggregation induced by ADP and the euglobulin lysis time (ELT)in rabbits were studied.RESULTS:As compared with the normal saline group,orientoside(1,2,and 4mg/kg)signi_ficantly prolonged the clotting time of mice in vitro,yet which had no significant influence on the systemic clots dissolution of mice;while orientoside(0.625,1.25 and 2.5 mg/kg)significantly prolonged the PT,KPTT and TT of rabbits,and significantly inhibited platelet aggregation of rabbits induced by ADP,yet which had no significant influence on the ELT of the rabbits.CONCLUSION:Orientoside can significantly inhibit the formation of thrombus.

Objective: To obtain the data of dental measurements in healthy Mongolia teenages.Methods: Normal dentognathic models were obtained by cephalometric roentgenography in 56 teenages (30 boys and 26 girls) aged 10～17 years. The width of the tooth crown, the size of the dental arch and dental base bone were measured with a vernier. The measurments were statistically analysed.Results: The tooth crown in boys was wider than that in girls( P 0.05). There was no significant difference in Bolton index and Point index between boys and girls.Conclusion: The dental measurments may be refrences for dental clinic and research.