1.Security of Long-Term Low-Dose Glucocorticoids Treatment on Infants with Asthma
Journal of Applied Clinical Pediatrics 2006;0(16):-
0.05).No partial side-effect of the medicine were discorvered in the observation process.Conclusion Long-term inspiration of low-dose GCS to treating the babies and infants with asthma has reliable security.
8.Combination of arterial infusion chemotherapy and embolization for the treatment of giant carcinoma of kidney in 32 cases
Fugui HUANG ; Zhen REN ; Xin QI
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To explore the efficacy of arterial infusion chemotherapy combined with embolization for the treatment of giant carcinoma of the kidney.Methods Arterial infusion chemotherapy combined with embolization was performed through the renal artery in 32 cases of giant carcinoma of the kidney from April 1990 to April 2003.The chemotherapeutic agents were epirubicin(30~40 mg),mitomycin(20~30 mg),and 5-FU(500 mg).The embolization was conducted with anhydrous alcohol,sodium morrhuate,and lipiodol plus gelatin sponge.Results The arterial infusion and embolization was successfully administered in all the 32 cases.Surgical resection was accomplished in 8 cases 1~3 months after the embolization,and little or no blood supply to the tumor was seen during the surgery.Pathological findings revealed marked necrosis of tumor cells with inflammatory cell infiltration around and fibrous proliferation as well as capillary embolization.The total response rate(CR+PR) was 87.5%(28/32) and the tumor decreased in size in 90.6% of the cases(29/32).The survival rates at 6 months,1-,2-,and 3-year were 78.1%(25/32),68.8%(22/32),46.9%(15/32),and 31.2%(10/32),respectively.The mean survival time was 41.5 months,with the longest time of 84 months.Conclusions Combination of infusion chemotherapy and embolization through the renal artery for the treatment of giant carcinoma of the kidney offers good clinical effects.
9.Follow-up study on executive function of frontal lobe in schizophrenics with and without homicide behaviors
Hongxing WANG ; Xin MA ; Wenfeng ZHEN
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):136-139
Objective To explore the characteristics of executive function and the changes of executive function in schizophrenics with and without homicide behaviors during follow-up.Methods Twenty-two schizophrenics with homicide behaviors (homicide group)and twenty-one schizophrenics without homicide behaviors (without-homicide group) were examined by Wisconsin Card Sorting Test(WCST),and followed up 3 months.All patients'clinical symptoms were evaluated by positive and negative symptom scale(PANSS)at the same time.Re-suits (1)At the baseline,homicide group showed higher score in complete lst category(R1st)than without-homicide group((28.64±32.73)vs(11.71±8.10),P=0.027)and no difference on other index.(2)No difference on WCST in homicide group between at the baseline and at three-month treatment (P>0.05).Without-homicide group at the baseline showed higher score in conceptual level responses than that of at three-menth treatment((46.80±27.04)vs.(65.02±21.32),P=0.048).(3)Homicide group at three-month treatment showed lower scores in positive scale,general psychopathology scale,PANSS total,thought disorder,activation,paranoid,aggressive than that of at the baseline(P<0.05).Without-hemicide group at three-month treatment showed lower scores in positive scale,negative scale,general psychopathology scale,PANSS total,thought disorder,activation,aggressive than that of at the haseline(P<0.01).(4)At the baseline,there was no correlation between WCST and PANSS in homicide group,only R1st score correlated with activation positively in without-homicide group(P<0.05).At three-month treatment, homicide group showed the score of failure to maintain set negatively correlated with negative scale,PANSS total, and aggressive(P<0.05).Conclusions Schizophrenics with homicide and without-homicide behaviors show executive function deficits.Homicide group shows more deficits in abstraction capacity than without-homicide group.
10.MYO minisatellite DNA probe and sub—cloning of MYO fragment
Chinese Journal of Immunology 1985;0(01):-
The initial study of the tumour DNA fingerprints using MYO minisatellite DNA probe wascarried out,and then,by means of DNA recombinant techniques,the fragment of MYO min-isatellite DNA probe obtained from plasmid pUC19-MYO was inserted into plasmid pGEM-4Z containing RNA polymerase promotor,thus a sub-clone refferred as pGEM-4Z-MYOwas constucted.That made an offer of the conditions of preparing RNA probe in order to in-cerase the sensitivities of DNA fingerprinting and laid a foundation for raised the efficiency of de-tecting the polymorphism of the minisatellite DNA.