Objective To investigate the clinical curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis.Methods A total of 76 patients with pulpitis and apicitis from Dec.2014 to Aug.2015 were collected and randomly divided into two groups, 38 cases in each group.Control group (65 tooth ) were treated by routine root canal therapy, with zinc oxide iodoform clove oil cement filling root canal;experimental group (71 tooth) were treated by routine root canal therapy, with calcium hydroxide paste filling root canal.Periodontal index, pain during root canal therapy ( IAE ) , serum inflammatory factors and clinical curative effect were observed and compared between two groups pre-and post-treatment.Results Compared with pre-treatment, periodontal index of PLI, BI, PD and GI in two groups were all lower (P<0.05), and IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05).Compared with control group, PLI, BI, PD and GI of experimental group were lower (P<0.05), IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05),too.The difference of IAE incidence between two groups was significant (P<0.01) and the clinical curative effect of experimental group was 88.73%, higher than 72.31% of control group (P<0.05).Conclusion Calcium hydroxide paste combine with root canal therapy in treatment of pulpitis and apicitis are effective, which can significantly improve periodontal condition of tooth, reduce the occurrence of pain during root canal therapy.

Adult ; Female ; Health Knowledge, Attitudes, Practice ; Health Services Needs and Demand ; Humans ; Male ; Middle Aged ; Occupational Health ; Steel

Adult ; Aged ; Aged, 80 and over ; Carbon Monoxide Poisoning ; complications ; Female ; Humans ; Interleukins ; blood ; Male ; Middle Aged ; Neurotoxicity Syndromes ; blood ; etiology

Objective To evaluate the value of clinical findings and different diagnostic criteria for the diagnosis of adult onset Still's disease (AOSD). Methods The AOSD patients admitted to Zhongshan Hospital affiliated to Fudan University from 2003 to 2009 were enrolled. Non-AOSD patients with fever were selected. Different diagnostic criteria of AOSD were applied to all patients. Two indenpendent samples t test and wilco-xon test were used for statistical analysis. Results The clinical features such as rash, arthralgia, arthroncus, sore throat, myalgia, lymph node enlargement, hepatomegaly, splenomegaly, leuko-cytosis, neutrophil ≥80% and serum level of ferrin≥ 2000 ng/ml hadhigher specificity (65.87%~98.41%) with 2.00～5.00 of the positive likelihood ratio.High fever ( ≥39.0℃), negative of ANA and RF had higher sensi-tivity (85.25%~93.65%). Combinations of three parameters such as high fever, rash, sore throat, leukocy-tosis, arthralgia had higher positive likelihood ratio. The specificity of ARA criteria was the highest. The sensitivity and accuracy of Yamaguchi criteria were the highest. Conclusion There is no single parameter that could be specific to the identification of AOSD. Combing with several parameters can improve the diagnostic efficiency. The results of this study have shown that the commonly used diagnostic criteria has high specificity.

Objective To detect the feasibility of patients with specific behaviors in the facial trauma clinical teaching. Method 47 medical students were randomly divided into experimental group ( n = 22 ) and control group(n=25). Students from experimental group at least dealed with 5 ～ 10 facial trauma patients with specific behaviors, while specific behaviors patients in control group were not more than 2. Teaching results were compared. Results There was no significant difference in operation test scores between the two groups ( (84.68 ±3.41 ) vs ( 83.96 ± 3.46 ), P = 0. 476 ). Composite score of teachers in the experimental group was significantly higher than that in control group( (90.09 ± 5.69 ) vs (83.48 ± 5.19), P ＜ 0.01 ). The results of questionnaire survey showed that two in five self-assessment results were higher in the experimental group(P ＜ 0. 01 ). Conclusion Medical students are more appropriately involved in treating special behaviors patients, which can improve the overall quality of students. Teaching with special behaviors patients has good effect, and is feasible.

0.05). Conclusions Low dose continuous infusion of CAZ to treat low respiratory infections is efficacious ,safe and economical.

Objective To know the effects of air pollution on the activity of aryl hydrocarbon hydroxylase (AHH) in the placenta tissue of women in Taiyuan, Shanxi Province. Methods The decrement of BaP after the metabolic procedure was used as the indicator of AHH activity. 151 lying-in women were selected and the AHH activity in the placenta was determined by fluorescence spectrophotometer, the precooling EDTA was added in the determination to inactivate AHH and to stop the reaction completely in order to get more stable result. Results The AHH activity in the placenta tissue increased as the atmospheric particle concentration and the BaP concentration in the particles increased. Conclusion The air pollution may induce the AHH activity increase in the placenta tissue of pregnant women in Taiyuan. The AHH activity can be used as the biological monitoring indicator in the PAHs polluted areas.

Objective To establish staff performance evaluation system of academy of medical sciences.Methods The Delphi method was employed.Results The main indicators of staff performance evaluation were selected by two-round of the Delphi method,and the evaluation system was established.Evaluation indicators covered different types of jobs of science research,medical services,disease prevention,medical education,science and technology support.Conclusions After two-round of consultation,there were more consistencies among experts regarding to selection of evaluation indicators.It will be tested and justified by further theoretical and empirical research.

Angiotensin II ; metabolism ; Cisplatin ; adverse effects ; Humans ; Kidney ; drug effects ; Kidney Diseases ; chemically induced ; metabolism

Objective To determine the value of dynamic contrast enhanced (DCE?MRI) in predicting treatment response before preoperative chemoradiotherapy in locally advanced rectal cancer. Methods A cohort of consecutive patients with histologically confirmed rectal adenocarcinoma treated with preoperative chemoradiotherapy followed by total mesorectal excision (TME) surgery was enrolled in a prospective, pilot trial. All enrolled patients were examined using DCE?MRI at two time points: 2 to 5 days before neoadjuvant chemoradiation, 1 to 4 days before surgery. The following perfusion parameters (Ktrans, Kep, Ve) were measured for tumor. The patients were classified into pathological complete response (pCR) and non?pCR group according to the pathological results after operation. Those perfusion parameters were compared between the pCR and the non?pCR group and between before and after CRT in pCR and the non?pCR group with the t test. Receiver?operating curves (ROC) were constructed to further investigate the predictive value of Ktrans, Kep, Ve before neoadjuvant chemoradiation and were used to determine a threshold value at which patents with pCR could be distinguished from patients without complete response. Results The final study population consisted of 38 patients. There were 12 patients with a pCR and 26 patients with non?pCR. Before neoadjuvant chemoradiation, the mean tumor Ktrans, Kep and Ve for pCR group were (1.25 ± 0.56)/min, (2.10 ± 1.61)/min and 0.73 ± 0.34, respectively, for non?pCR group they were (0.46 ± 0.39)/min, (1.15 ± 0.77)/min and 0.32±0.12, respectively. All perfusion parameters showed significant difference between those two groups(t values were 3.45,5.67 and 6.23 respectively, all P<0.05). After neoadjuvant chemoradiation, the mean tumor Ktrans, Kep and Ve for pCR group were (0.28 ± 0.13)/min, (0.62 ± 0.27)/min and 0.21 ± 0.13 respectively, for non?pCR group, they were (0.32±0.12)/min, (0.83±0.42)/min and 0.17±0.10, respectively. All perfusion parameters showed no difference between those two groups(P>0.05), as well as the changes before and after neoadjuvant chemoradiation in those groups(P>0.05). ROC analysis for Ktrans pre?treatment revealed that Ktrans had an AUC of 0.837 in predicting pCR. A Ktrans of 0.66/min was emerged as the optimal cut?off for distinguishing pCR from non?pCR and for Ktrans>0.66/min, the sensitivity and specificity for predicting pCR were 75.0% (9/12) and 96.2% (25/26). Kep and Ve showed an AUC of 0.655 and 0.654 in predicting pCR. Conclusions In locally advanced rectal cancer, DCE?MRI can aid in predicting treatment response before preoperative chemoradiotherapy. Ktrans may become a better predictor to classify which patients will benefit from neoadjuvant chemoradiation.