1.Curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):79-81
Objective To investigate the clinical curative effect of calcium hydroxide paste combined with root canal in treatment of pulpitis and apicitis.Methods A total of 76 patients with pulpitis and apicitis from Dec.2014 to Aug.2015 were collected and randomly divided into two groups, 38 cases in each group.Control group (65 tooth ) were treated by routine root canal therapy, with zinc oxide iodoform clove oil cement filling root canal;experimental group (71 tooth) were treated by routine root canal therapy, with calcium hydroxide paste filling root canal.Periodontal index, pain during root canal therapy ( IAE ) , serum inflammatory factors and clinical curative effect were observed and compared between two groups pre-and post-treatment.Results Compared with pre-treatment, periodontal index of PLI, BI, PD and GI in two groups were all lower (P<0.05), and IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05).Compared with control group, PLI, BI, PD and GI of experimental group were lower (P<0.05), IL-6, IL-8, IL-1βand TNF-αwere lower(P<0.05),too.The difference of IAE incidence between two groups was significant (P<0.01) and the clinical curative effect of experimental group was 88.73%, higher than 72.31% of control group (P<0.05).Conclusion Calcium hydroxide paste combine with root canal therapy in treatment of pulpitis and apicitis are effective, which can significantly improve periodontal condition of tooth, reduce the occurrence of pain during root canal therapy.
2.Clinical study of low dose continuous infusion of ceftazidime (CAZ)forthe treatment of low respiratory tract infections
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
0.05). Conclusions Low dose continuous infusion of CAZ to treat low respiratory infections is efficacious ,safe and economical.
3.Air Pollution on Activity of Aryl Hydrocarbon Hydroxylase in Placenta Tissue of Women in Taiyuan
Heng GU ; Yinlong JIN ; Zhen XU
Journal of Environment and Health 2007;0(11):-
Objective To know the effects of air pollution on the activity of aryl hydrocarbon hydroxylase (AHH) in the placenta tissue of women in Taiyuan, Shanxi Province. Methods The decrement of BaP after the metabolic procedure was used as the indicator of AHH activity. 151 lying-in women were selected and the AHH activity in the placenta was determined by fluorescence spectrophotometer, the precooling EDTA was added in the determination to inactivate AHH and to stop the reaction completely in order to get more stable result. Results The AHH activity in the placenta tissue increased as the atmospheric particle concentration and the BaP concentration in the particles increased. Conclusion The air pollution may induce the AHH activity increase in the placenta tissue of pregnant women in Taiyuan. The AHH activity can be used as the biological monitoring indicator in the PAHs polluted areas.
4.Application of patients with specific behaviors in the facial trauma clinical teaching
Zhen YANG ; Fazhi QI ; Jianying GU
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(11):1029-1030
Objective To detect the feasibility of patients with specific behaviors in the facial trauma clinical teaching. Method 47 medical students were randomly divided into experimental group ( n = 22 ) and control group(n=25). Students from experimental group at least dealed with 5 ~ 10 facial trauma patients with specific behaviors, while specific behaviors patients in control group were not more than 2. Teaching results were compared. Results There was no significant difference in operation test scores between the two groups ( (84.68 ±3.41 ) vs ( 83.96 ± 3.46 ), P = 0. 476 ). Composite score of teachers in the experimental group was significantly higher than that in control group( (90.09 ± 5.69 ) vs (83.48 ± 5.19), P < 0.01 ). The results of questionnaire survey showed that two in five self-assessment results were higher in the experimental group(P < 0. 01 ). Conclusion Medical students are more appropriately involved in treating special behaviors patients, which can improve the overall quality of students. Teaching with special behaviors patients has good effect, and is feasible.
5.Serum levels and clinical significance of IL in patients with delayed encephalopathy after acute carbon monoxide poisoning.
Long ZHEN ; Ren-jun GU ; Ping ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(9):561-562
Adult
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Aged
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Aged, 80 and over
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Carbon Monoxide Poisoning
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complications
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Female
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Humans
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Interleukins
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blood
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Male
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Middle Aged
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Neurotoxicity Syndromes
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blood
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etiology
7.Build Staff Performance Evaluation System of Medical Research Institutes
Youqin HE ; Jingliang GU ; Tianmin ZHEN
Chinese Journal of Medical Science Research Management 2016;29(3):209-212
Objective To establish staff performance evaluation system of academy of medical sciences.Methods The Delphi method was employed.Results The main indicators of staff performance evaluation were selected by two-round of the Delphi method,and the evaluation system was established.Evaluation indicators covered different types of jobs of science research,medical services,disease prevention,medical education,science and technology support.Conclusions After two-round of consultation,there were more consistencies among experts regarding to selection of evaluation indicators.It will be tested and justified by further theoretical and empirical research.
8.Diagnostic analysis of different index in adult onset Still's disease
Zhen WANG ; Lindi JIANG ; Jie GU
Chinese Journal of Rheumatology 2010;14(3):192-194
Objective To evaluate the value of clinical findings and different diagnostic criteria for the diagnosis of adult onset Still's disease (AOSD). Methods The AOSD patients admitted to Zhongshan Hospital affiliated to Fudan University from 2003 to 2009 were enrolled. Non-AOSD patients with fever were selected. Different diagnostic criteria of AOSD were applied to all patients. Two indenpendent samples t test and wilco-xon test were used for statistical analysis. Results The clinical features such as rash, arthralgia, arthroncus, sore throat, myalgia, lymph node enlargement, hepatomegaly, splenomegaly, leuko-cytosis, neutrophil ≥80% and serum level of ferrin≥ 2000 ng/ml hadhigher specificity (65.87%~98.41%) with 2.00~5.00 of the positive likelihood ratio.High fever ( ≥39.0℃), negative of ANA and RF had higher sensi-tivity (85.25%~93.65%). Combinations of three parameters such as high fever, rash, sore throat, leukocy-tosis, arthralgia had higher positive likelihood ratio. The specificity of ARA criteria was the highest. The sensitivity and accuracy of Yamaguchi criteria were the highest. Conclusion There is no single parameter that could be specific to the identification of AOSD. Combing with several parameters can improve the diagnostic efficiency. The results of this study have shown that the commonly used diagnostic criteria has high specificity.
9.Effects of Components of Medium for Photo-synthetic Bacteria on its Synthesizing Carotenoid
De-Ming CHEN ; Yong-Bin HAN ; Zhen-Xin GU ;
Microbiology 1992;0(03):-
The medium of photo-synthetic bacteria synthesizing carotenoid was optimized with response surface methodology. The regression equation expressing the relationship between carotenoid yield and main components of culture medium was established by stepwise analysis. The R-squared in the model of regression equation was 0. 958, which meant the established equation could predict the carotenoid yield well at the range of factors in this design. It was indicated that the optimum medium components were: 0. 81% citric acid, 0. 35% NH4Cl and 0. 18% corn syrup. On those conditions, it was predicted that the highest production of carotenoid was 13. 34 mg/L, which was 2. 04 times higher than initial carotenoid yield before optimization.
10.DISTRIBUTION AND ORIGINS OF THE NITRERGIC PERIVASCULAR NERVES IN RAT CEREBRAL ARTERIES
Diansan SU ; Zhen GU ; Heming WANG ; Qunying HAN ;
Acta Anatomica Sinica 1954;0(02):-
Objective To observe the distribution and origins of the nitrergic perivascular nerves in rat cerebral arteries with a histochemical method for reduced nictinamide adenine dinucleotid phosphate(NADPH) diphorase activity, after resecting the membraneous structure at the ethmoidal formen. Methods Health adult SD rats were randomly distributed to three groups:sham operation group(group A), unilateral (right) operation group(group B), and bilateral operation group (group C). Both group B and C were further divided into two groups: group of resection of membraneous structure and nasociliary nerve (group BⅠ,CⅠ), and group of only removing membraneous structure (group BⅡ, CⅡ). On the seventh day after operation, the pterygopalatine ganglia and otic ganglia of group A were taken, and striped the cerebral arteries of three groups. With the method of NADPH d we investigated the positive cells in pterygopalatine ganglia, otic ganglia, and the changes of positive perivascular nerve fibers. Results A great deal of NADPH d positive cells were found in both pterygopalatine ganglia and otic ganglia. After unilateral operation, the NADPH d positive nerves in the ipsilateral middle cerebral artery(MCA) completely disappeared, but it did not change on the contralateral MCA. The positive nerves on basal artery(BA) and bilateral posterior cerebral artery(PCA), internal carotid artery(ICA), and anterior cerebral artery (ACA), obviously decreased. After bilateral operation, the positive nerve fibers in all arteries except ACA disappeared. There were no significant difference between group BⅠ and BⅡ; CⅠ and CⅡ.Conclusion There were nitrergic nerve fibers in all major cerebral arteries, and the density of positive nerve fibers in the anterior circulation of the cerebral artery was higher than that of posterior one. Different cerebral arteries have different origins of nitrergic nerve. The nitrergic nerve in BA, PCA and ICA completely originated from ipsilateral pterygopalatine ganglia; the nitrergic nerves of MCA were completely originated from ipsilateral pterygopalatine ganglion; ACA have more sources of nitrergic nerves other than bilateral pterygopalatine ganglia. Nasociliary nerve from trigeminal ganglion did not involve in the origins of nitrergic perivascular nerves in rat cerebral arteries. [