1.Sonographic features of follicular thyroid carcinoma th
Chinese Journal of Medical Ultrasound (Electronic Edition) 2013;(6):484-488
Objective To determine sonographic features of thyroid follicular carcinoma ( FC) in comparison with thyroid follicular adenoma ( FA ).Methods This retrospective study included 36 pathologically proven FCs (5 widely invasive FCs and 31 minimally invasive FCs)and 52 FAs in 88 patients who underwent thyroid surgery .We analyzed clinical features of each patient ,including patient gender,age, and sonographic features of each tumor , including maximum diameter, peripheral halo, echogenicity, echotexture,calcifications and nodule number .These clinical and sonographic findings were compared by using t test ( age and diameter ) or the χ2 test (sex ratio,halo,echogenicity,echotexture,calcifications and nodularity)between FAs and FCs.Results For sonographic features,predominantly solid content(100.0%, 36/36),hypoechoic echogenicity (69.4%,25/36),inhomogeneous echotexture (83.9%,26/32),presence of calcifications(55.6%, 20/36) and without or with irregular halo (69.4%,25/36) were more commonly found in FCs.In comparison,FAs were more likely to present with mixed or predominantly cystic content (61.5%,32/52),isoechoic echogenicity (63.5%,33/52),homogeneous echotexture (80.8%,42/52), absence of calcifications (7.7%,4/52) and thin halo (86.5%,45/52) ( χ2 =34.813,28.596,35.256, 25.052,28.811,all P<0.01).The maximum diameter and mean age did not show statistically significant difference between FCs and FAs (t=0.222,-1.228,P=0.825,0.223).The proportions of tumor larger than 40 mm(22.2%,8/36 vs 17.3%,9/52),solitary nodule(31.3%,12/24 vs 21.2%,11/41),male sex (25.0%,9/27 vs 23.1%,12/40)and patient older than 45 years(66.7%,24/36 vs 71.2%,37/52)did not show statistically significant difference between FCs and FAs ( χ2 =0.330,1.635,0.043,0.201,all P>0.05).Conclusion Sonographic features,including predominantly solid content ,hypoechoic echogenicity, inhomogeneous echotexture ,presence of calcifications and without or with irregular halo were more commonly seen in FCs.
3.Arthroscopic treatment of developmental dislocation of the hips in infants
Wenzhe YIN ; Bing CUI ; Zhen XUE
Orthopedic Journal of China 2006;0(15):-
0.05).[Conclusion]The factors causing reductions should be removed arthroscopically.Arthrocopy may be a useful micro-treatment method for DDH.
6.Permeability increase of prostate cancer cells membrane under low intensity ultrasound in vitro
Ji-zhen, ZHANG ; E, SHEN ; Bing, HU
Chinese Journal of Medical Ultrasound (Electronic Edition) 2010;07(12):2025-2030
Objective To investigate the permeability changes of prostate cancer cells membrane under low intensity ultrasound in vitro.Methods The culture of monolayer adherent LNCaP prostate cancer cells in six-well plate was exposed to continuous ultrasound at frequency of 1 MHz.The cells membrane permeability (stained with Calcein)and cells viability(stained with PI)were evaluated by fluorescent microscope (FM) and cells morphological changes were evaluated by scanning electron microscope (SEM) under ultrasound with acoustic intensity of 160 mW/cm2 for 5 s.The rate of cells with increased cells membrane permeability as function of acoustic intensity (80 mW/cm2,120 mW/cm2 and 160 mW/cm2,for 5 s) and exposure duration (5 s,10 s and 15 s,acoustic intensity of 120 mW/cm2) was evaluated by flow cytometry.ResultsAfter low intensity of ultrasound,the cells with increased cell membrane permeability could be clearly shown with Calcein uptake under FM while no cell showed Calcein uptake in the control group.The SEM showed less microvilli on the cells after low intensity of ultrasound exposure and few cells showed holes on the cell membrane.The rate of cells with increased membrane permeability increased with acoustic intensity and exposure duration.Conclusion Low intensity ultrasound alone could increase membrane permeability of prostate cancer cells and cells with increased membrane permeability showed surface plane,uncommon holes on the cells membrane.The rate of cells with increased membrane permeability positively correlated with acoustic intensity and exposure duration.
7.Clinical investigation of six cases with mandibular first premolars with three canals.
Bing-zhen HE ; Xing-zhe YIN ; Qian-qian WANG
Chinese Journal of Stomatology 2008;43(10):623-624
Adult
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Aged
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Female
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Humans
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Male
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Middle Aged
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Molar
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Root Canal Therapy
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methods
8.mircoRNA and gastric cancer: an update.
Zhen JIANG ; Jun-ming GUO ; Bing-xiu XIAO
Chinese Journal of Pathology 2008;37(8):558-560
10.Analysis of three serological tests results of hemolytic disease of newborn in 1 350 cases
Yingying GUO ; Zihan HUO ; Zhen WANG ; Bing LIU
Chinese Journal of Immunology 2016;32(9):1357-1359,1363
Objective:To explore blood type distribution of newborns hemolytic disease ( HDN ) caused by maternal and neonatal blood type incompatibility and analyze the value of hemolysis three trials in the diagnosis of HDN.Methods:Hemolysis three trials of type O or Rh negative maternal cord blood samples and hyperbilirubinemia of the newborn blood samples from January 2014 to 2016 were detected by micro-column gel test cards.Then the results were statistically analyzed.Results:(1) There were 918 cases of maternal and neonatal blood type incompatibility in all 1350 cases.569 cases were detected HDN positive with the rate of 62%( 569/918).Among 569 cases,the positive rate of direct anti-globulin test,free antibody test and antibody released test were 27.9%(159/569),86.5%(492/569) and 100% respectively.There was statistical difference of the combination of direct anti-globulin test negative,free antibody test positive and antibody released test positive compared with other combinations ( P<0.05 ).( 2 ) There was statistical difference of HDN positive rate between ABO 73.8%(551/747) and Rh 10.5%(18/171)in 918 cases of blood type incom-patibility.(3)There was statistical difference between A positive rate of 80%(280/350) and B positive rate of 68.3%(271/397) in 747 cases of ABO incompatibility.(4)There was statistical difference among RhD positive rate of 17.7%(14/79),RhE positive rate of 6.8%(4/59) and RhC positive rate of 0(0/33).Conclusion: Antibody released test was the most sensitive test in hemolysis three trials to diagnose HDN.The probability of HDN positive caused by maternal and neonatal ABO blood type incompatibility was significantly higher than Rh.The probability of HDN positive with type A newborns was significantly higher than type B.The probability of HDN positive caused by RhD blood type incompatibility was significantly higher than RhE and RhC.