Objective To analyze the epidemic situation of brucellosis in Shenyang,reveal its epidemic characteristics,and provide scientific basis for prevention and control of brucellosis.Methods The epidemiological data of brucellosis in Shenyang in 2016 and 2017 were collected from the "Infectious Disease Reporting Information Management System" and the questionnaires of confirmed cases of brucellosis in Shenyang.Descriptive epidemiological method was used to analyze the "three-way distribution" of brucellosis and the time interval of case diagnosis,discovery agency and infection route.Results In 2016 and 2017,910 cases of brucellosis were reported in Shenyang,with an average incidence of 5.52/100 000.The incidence of brucellosis was mainly concentrated in March-August (627 cases),with the highest incidence in May (139 cases),accounting for 15.27％.There were brucellosis cases reported in 13 counties (cities and districts) of Shenyang,among which Xinmin City was the largest (341 cases),accounting for 37.47％;including 667 males and 243 females,with a sex ratio of 2.47:1.00;the 45-49 age group was the most (168 cases),accounting for 18.46％;the farmer was the most (555 cases),accounting for 60.99％.The average time interval of case diagnosis was 26 d,the shortest was 0 d and the longest was 252 d,and the confirmed case within 8-30 d was the most (432 cases),accounting for 47.47％.Totally 491 cases were found by Shenyang Infectious Diseases Hospital,accounting for 53.96％;the remaining 419 cases were found by hospitals at all levels,accounting for 46.04％.The main infection route was feeding and herding (616 cases),accounting for 67.69％.Conclusions There are obvious regional,seasonal,gender,age and occupational differences in the occurrence of brucellosis.Some cases of brucellosis are diagnosed for a long time.It is necessary to carry out brucellosis surveillance for key groups,carry out health education for occupational groups and improve the diagnostic level of brucellosis by primary clinicians.