Objective To investigate the value of left ventricular function in patients with chronic pulmonary heart disease(CPHD) using strain rate imaging (SRI).Methods This study included 64 patients with CPHD (30 patients with compensatory function and 34 with decompensatory function) and 30 normal control.Peak systolic strain rate (SRs),peak early diastolic strain rate (SRe) and peak late diastolic strain rate (SRa)of left ventricular basal and middle segments were measured,and then mean peak strain rate (mSR) was calculated.The above digital parameters were analyzed compared with the conventional echocardiographic indices.Results The indices (mSRs,mSRe,mSRe/mSRa)in CPHD were reduced and mSRa increased as compared with those in controls (all P=0.000).And the above indices showed the same change when decompensatory group was compared with compensatory group (P=0.000,0.038,0.015,0.001).Negative correlation was noted between LVEF and mSRs in patients with CPHD (r=0.75,0.82;P=0.000).Conclusions LVEF is negatively related with mSRs in CPHD patients.mSRs can reflect the status of left ventricular function.SRI is a more sensitive tool in quantitative evaluation of left function of CPHD.

on,size and the extent structures of atrial septal defect on line.

Objective To investigate whether myocardial perfusion impairment and left ventricular (LV) longituadinal systolic dysfunction had happened in patients with coronary slow flow(CSF),and to assess the relationship between them by myocardial contrast echocardiography(MCE) and speckle tracking imaging(STI).Methods A total of 55 patients underwent coronary angiography for angina were enrolled,of those 35 with coronary slow flow phenomenon as CSF group,20 patients with normal coronary angiography as control group.STI and MCE were performed from the apical 4-,3 and 2 chamber views at baseline and after low-dose dobutamine stress echocardiography (LDDSE) in CSF group and control group.STI derived LV global longitudinal strain(GLS) and GLS amplitude of variation(△GLS),and MCE derived myocardial blood flow(MBF),and myocardial flow reserve (MFR) were obtained.And the correlation between GLS/△GLS and MBF/MFR was analyzed.Results At baseline,the GLS and MBF were similar between CSF group and control group(P ＞0.05).After LDDSE,both GLS and MBF were significantly increased in two groups (P ＜0.05).The GLS,△GLS,MBF,and MFR in CSF group were significantly lower than those in control group(P ＜0.05).There was no significant correlation between GLS and MBF at baseline in the CSF group(r =-0.274,P =0.111).However,after LDDSE significant correlation existed between GLS and MBF(r =-0.630,P =0.000).Conclusions LV longituadinal systolic function is impaired in patients with CSF under dobutamine stress test,the impairment of MBF and MFR could be an important contributor to the decrease of LV longituadinal systolic function.

Infant, Newborn ; Infant ; Female ; Humans ; Infant, Extremely Premature ; Uterus ; Gestational Age