Project supervision and management with a focus on project performance is an important measure to achieve project objectives and meet the need for scientific management of public health projects. Currently, many models widely used internationally are faced with limitations when used domestically. Research in the paper is based on the three basic problems that exist in the process of domestic health project evaluations, combines the practices of the National Health and Family Planning ( NHFPC) Center for Project Supervision and Management, and proposes the logical framework of the compound evaluation model according to the theoretical assumptions behind health project evaluations. Complex health project evaluations should bear a proper understanding of the basic concept of evaluative features with a focus on project results and effects and importance attached to an analysis of factors that impact project implementation.

Objective To observe the effects of early intelligent feedback rehabilitation training system of lower extremities on walking ability in stroke patients with hemiplegia. Methods Forty post-stroke hemiplegic patients (onset <1 month)were enrolled. They were randomly divided into either an intelligent feedback rehabilitation group or a conventional rehabilitation group by the admission numbers (n=20 in each group). The rehabilitation training began at 48 hours after patient′s condition stabled. The conventional rehabilitation group received conventional rehabilitation training only,and on this basis,the patients of intelligent rehabilitation group underwent walking ability training using intellectual feedback rehabilitation training system of lower extremities. The walking ability of lower-extremity of the patients was evaluated with the Fugl-Meyer Assessment Scale (FMA-L)and Holden Walking Classification. The changes of the tension and strength of tibialis anterior muscle and gastrocnemius muscle were evaluated by the surface myoelectric signals. Results Before treatment,there were no significant differences in FMA-L scores and Holden walking function classification between the two groups (P>0. 05). Four weeks after treatment, the FMA-L scores were improved in both the intelligent and conventional rehabilitation groups compared to before treatment (P<0. 01);the differences were 20. 0 ± 6. 2 and 5. 1 ± 1. 6 respectively before and after treatment. The degree of improvement of the intelligent rehabilitation group was better than that of the conventional rehabilitation group (P<0. 01). Holden walking function classification showed that only the intelligent rehabilitation group was improved as compared to before treatment (P<0. 01). Four weeks after treatment ,the strength and tone of the tibialis anterior muscle and gastrocnemius muscle of both groups were increased compared to before treatment (P <0. 01 ). The differences of the strength and tone of the tibialis anterior muscle were 20 +7 and 12 +4μV respectively in the rehabilitation groups before and after treatment,and those were 12+4 and 9+3μV in the conventional rehabilitation group;the differences of the strength and tone of the gastrocnemius muscle of the intelligent rehabilitation group were 25+8 and 19+6μV respectively before and after treatment,and those of the conventional rehabilitation group were 10+3 and 11+2μV respectively. There was significant difference between the intelligent rehabilitation group and the conventional rehabilitation group (P <0. 01 ). Conclusion The treatment of early intelligent feedback rehabilitation training system of the lower extremities may significantly improve the walking ability of the lower extremities in stroke patients with hemiplegia.

Objective　To synthesize the artificial antigen methylparaoxon （M1600）.Methods　Methylparaoxon was reduced into amino-methylparaoxon by using acetic acid-zinc power-hydrochloric acid. Artificial antigens M1600-BSA， M1600-TTH　were synthesized by conjugating amino-methylparaoxon to bovine serum albumin （BSA）and tachypleus tridentatus hemocyanin （TTH）directly after diazotization.Results　 Rabbits had been immunized with M1600-BSA for 10 weeks， and the high titer and high specificity antiserum from those rabbits was testified by doubled agar gel diffusion and indirect ELISA．Conclusion　An artificial antigen was obtained successfully and this made it possible to establish the immunoassay of M1600.

Objective To investigate a antitumor effects of mouse original monoclonal antibody against hMIC -1 as intravenous administration with human pancreatic tumor in vivo and providing experimental data .Methods The fourty-eight mice were randomized into eight groups for loaded with two pancreatic tumor cell lines panc -1 or sw1990 respectively , and individual tumor growth was observed , antitumor efficacy was evaluated after using mouse original monoclonal antibody against hMIC-1 by intravenous administration .The pathological change with formalin fixed , paraffin embedded tissues section was viewed .Results There was a significant difference in tumor volume and weigt in intravenous injection of mouse original monoclonal antibody against hMIC-1 on load pancreatic tumor with nude mice group compared with that in the control group after four week treatment , and the mouse original monoclonal antibody against hMIC-1 demonstrated a close association between inhibition of tumor volume growth and dose-effective in the two xenograft models examined .Under examined microscope , the pancreatic tumor tissue was destroyed evidently in mouse original monoclonal antibody against hMIC-1 group.Conclusions The antitumor effect of intravenous injection for mouse original monoclonal antibody against hMIC-1 is better than that of systemic using gemcitabine .

Objective To explore the risk factors of recurrent cerebral infarction and the preventive meas-ures. Methods The risk factors were compared between recurrent group (246 cases with recurrent cerebral infarc-tion) and unrecurrent group( 100 cases with unreeurront cerebral infarction) by means of multiple logistic regression analysis. Results The recurrent cerebral infarction is correlated closely with hypertension, diabetes, heart diseases and excessive drinking, and the OR values arc 2.206, 2.232, 2.252, 2.842, 2.366 respectively (P<0.05), prophy-lactic treatment had the protective effects against the recurrent cerebral infarction,and the OR value was 0.249. Con-dusions The main risk factors of recurrent cerebral infarction were hypertension,heart diseases,excessive drinking. Prophylactic treatment hed great significance in preventing the recurrence of cerebral infarction.

Objective To improve the knowledge of CT appearances of spondylolysis of the lumbar spine.Methods 32 patients with lumbar spinal spondylalysis were examed by Elscint 2400 CT.CT appearances were analyzed.Results The CT feature of spondylolysis was loop-broken sign.Spondylolisthesis was present in 25 cases,the CT mainfestations included the increased anterior pasterior diameter of spinal canal,wich sign,deformity of vertebral canal and pseudobulging disk.Other features included asymmetrical zygapophysial joints.Conclusion “loop-broken sign” is a relatively specific CT appearance of spondylolysis of the lumbar spine,which is significant in diagnosting spondylolysis without spondylolisthesis.

The goal of China's health care insurance system is to improve the fairness and accessibility of health care services for low-income people. In the past 10 years of practice, the insurance has made remarkable a-chievements and gained popularity among broad masses of people. With the support of World Bank and UK Depart-ment for International Development, China Rural Health Development Project ( hereinafter referred as Health XI Project) have used the advantages of unique funding, management and human resources to launched a series of pro-ject activities, with the main goal of achieving effective convergence between the New Rural Cooperative Medical Scheme (NRCMS) and Healthcare Financial Assistance Program (HCFAP) in order to explore the assistance system of catastrophic diseases. Some areas have achieved seamless convergence between NRCMS and HCFAP to explore the assis-tance program for catastrophic diseases in the context of confirming and optimizing the management of services covered by the project, especially conducting a series of exploration and practice activities in the aspects of increasing new funding channels to establish theCatastrophic Disease Assistance Fund, strengthening the related supporting regulations, etc. The results show that the utilization of services covered by HCFAP in the project has significantly improved, the protection level of health insurance has greatly improved, and the people satisfaction has significantly increased.

Objective To investigate the effect of Rb protein expression on the clinical response of the colorectal cancer patients perfused with 5-Fu before operation. Methods The expression of Rb protein in 34 cases of the colorectal cancer sample was determined by streptavidin-peroxidase(S-P) immunohistochemical method and the positive reactions were analysed by ICM-100 Cell DNA Picture Analysis System. The apoptotic rate of colorectal cancer cells was examined by the TUNEL staining. The chemosensistivity of the colorectal cancer cells were tested by the MTT colorimetric assay of agar culture. The clinical response of the colorectal cancer patients perfused with 5-Fu before operation was observed simultaneously. Results ⑴There was the negative correlation between the resistance index of the colorectal cancer cells to 5-Fu (IC50/10-1 peak concentration) and the apoptotic rate of the colorectal cancer cells induced by 5-Fu (?=-0.53,t=-4.91,P1.0 belongs to the group of resistance,

Objective To observe the response of activated microglia/macrophages within and around the lesion site after rats' spinal cord injury treated with chitosan.Methods 35 adult female Wistar rats were randomly divided into the sham group (n=5), completely transection group (n=15) and chitosan treated group (n=15). The responses of activated microglia/macrophages on the 1st day, 3rd day, 7th day, and in the 2nd week and 4th week after surgery were examined by immunohistochemistry.Results Microglia/macrophages were fully activated and the number of these cells increased and got the highest level on the 3rd day post injury, then quickly decreased. In the chitosan treated animals, the microglia/macrophages were fully activated and the number increased to peak on the 7th day, then quickly decreased, there were still a few microglia/macrophages around the wound in the 2nd to 4th week after the treatment.Conclusion Microglia/macrophages could be recruited within and around the lesion area longer when treated by chitosan.