1.Strengthening the Teaching And Construction of Preventive Medical Speciality
Chinese Journal of Medical Education Research 2003;0(04):-
In this paper graduation field work of students of one grade majoring in preventive medicine is investigated by means of questionnaire and making a diary for practice.The investigation shows that the major difficulty for the practical units to admit trainees is no housing.In spite of this,most of the units welcome the students and devote much attention to guiding practice.Generally,they can arrange for interns to practice in different departments according to the time and the contents of the practice plan.Different units have different practice situations.Each unit has a good evaluation of our school's students,except for the operation skill.The writers hereby have offered concrete suggestions on how to solve the problems.
2.Analysis of the prevalence and affecting factors of hyperuricemia in middle and old aged people in longevity areas of China
Jianwei XU ; Yi ZHAI ; Zhaoxue YIN ; Xiaoming SHI ; Yuzhi LIU ; Yi ZENG
Chinese Journal of Rheumatology 2011;15(3):155-158
Objective To describe the prevalence of hyperuricemia of centenarians in longevity areas of China and the risk factors were analyzed. Methods All centenarians in 7 longevity areas were selected,and people aged 40 ~, 60 ~, 80 ~ and 90 ~ were selected randomly in the same 7 areas. The data of demographic data, dieting habits and diseases history were collected by questionnaire survey. Hyperuricemia and associated risk factors, physical examination and biochemical tests were collected. Logistic regression was used to analyze the hypemricemia and its relevant factors. Results The highest prevalence of hyperuricemia was found in centenarian men, which was 12.73%, the highest prevalence of hyperuricemia among 90~ women was 18.75%. The hyperuricemia group were more prone to have hypertension, diabetes, renal function decreased, hypercholesterolemia, hypertriglyceridemia, high density lipoprotein. Logistic regression analysis showed that renal function declined, high TG, high density lipoprotein hyperlipidemia, blood urea nitrogen increased, drinking were risk factors for hyperuricemia. Conclusion The prevalence of hyperuricemia in people older than 90 years and above in longevity areas is high. The results suggest that the treatment strategy for hyperuricemia should be a comprehensive one that combines preventive measures with medication interventions.
3.Association between elevated serum high sensitive C-reactive protein and renal function among longevous people in China
Yi ZHAI ; Jianwei XU ; Xiaoming SHI ; Zhaoxue YIN ; Yi ZENG ; Yuzhi LIU
Chinese Journal of Geriatrics 2013;(3):296-299
Objective To explore the relationship between high sensitive C-reactive protein (hsCRP) and renal function among people aged 90 years and over in longevity regions in China.Methods Totally 506 subjects aged 90 years and over in 5 longevity areas from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) 2008-2009 were included in the study.Demographic,behavioral and lifestyle parameters and self-reported chronic diseases were collected by general health-related questionnaire.We conducted the physical examination and also measured serum hsCRP and other indicators of renal function.Logistic regression was used to analyze the relationship between hsCRP and renal function.Results The prevalence of elevated hsCRP was 36.6% in people aged 90 years and over,43.0% in male and 34.8% in female.No significant gender difference was observed among them (x2 =2.4184,P=0.1199).The prevalence of elevated hsCRP were 34.4% in 90-99 years group and 39.2% in the centenarian group,and there was no significant difference between the two groups (x2 =1.2425,P =0.2650).We found significant statistical difference in prevalence of elevated hsCRP between declined renal function group (42.0%) and normal group (33.3%) (t=3.8450,P=0.0499).The level of serum creatinine were (89.5±37.4) μmol/L in elevated hsCRP group and (81.5±31.4) μmol/L in the normal hsCRP group among the people aged 90 years and over.Significant difference was found between the elevated and normal hsCRP group (x23.8450,P=0.0161).In the multivariate logistic regression analysis,the risk factors of renal function decline were female,smoking,hypertension,hyperuricemia and elevated hsCRPCOR=1.676 (95%CI:1.091-2.573)].Conclusions Elevated hsCRP increases the risk of renal function decline among people aged 90 years and over in China.
4.Effects of perinatal and postnatal cytomegalovirus infection on infantile physical and neuro-psychological development
Zhaoxue MENG ; Huiying CUI ; Huihong ZHU ; Boxin ZHANG ; Hua HUANG ; Jingyu DONG ; Nanfeng LIU ; Haiyan JIANG ; Fangsheng XU
Chinese Pediatric Emergency Medicine 2010;17(6):508-510
Objective To study the effects of perinatal and postnatal cytomegalovirus(CMV) infection on infantile physical development and nerves mental growth. Methods We observed forty-eight cases of perinatal and postnatal CMV infection infants and twenty-two cases of non-CMV infected infants. We compared the physical development between two groups at birth ,3 months and 1 year of age, and evaluated development quotient (DQ) at 1 year of age. Results There were no significant differences of baby length,weight, head circumference between two groups at birth and 3 months (P > 0.05). The averages of baby length,weight,and head circumference were all in the normal range,which showed no significant differences between two groups(P > 0. 05). There were no significant differences in DQ of rough movement,accurate movement, adaptability, language and sociality ability between two groups at 1 year of age (P > 0.05). The averages of total DQ were in the normal range, which showed no significant difference between two groups as well (P > 0. 05). According to the evaluation hierarchies, DQ values of two groups were mostly in normal level range, and there also was no significant difference(x2 = 1. 026, P > 0. 05). Conclusion The perinatal and postnatal cytomegalovirus(CMV) infection has no significant adverse effects on infantile physical development and neuro-psychological development.
5.Association between oxygen saturation and cognitive function in older adults from longevity areas in China
Liqin SU ; Zhaoxue YIN ; Ning XU ; Yuebin LYU ; Jiesi LUO ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2016;50(7):600-604
Objective To explore the relationship between oxygen saturation (SpO2) and cognitive function in older adults from longevity areas in China. Methods A total of 2 285 participants aged ≥65 years according to the 2012 Chinese Longitudinal Healthy Longevity Survey were included in this study. Among them, 1 739 participants aged 65-99 years were randomly selected, and 546 participants aged≥100 years were totally involved. A standardized questionaire was used to collect the information of demographic characteristics, life styles, disease history, etc. Cognitive function was evaluated using the Mini Mental State Examination Scale. Arterial oxygen saturation and heart rate were measured by pulse oximetry. Differences in cognitive function between the low SpO2 group (<0.94) and normal SpO2 group (≥0.94) were analyzed, and logistic regression models were used to analyze the relationship between SpO2 and cognitive function. Results The total score of cognitive function was 22.6 ± 9.7 for the 1 922 participants in the normal SpO2 group, and 18.8 ± 11.0 for the 363 participants in the low SpO2 group (t=6.11, P<0.001). The proportion of cognitive impairment in the low SpO2 group was 36.6% (n=133), and 22.9% (n=441) in the normal SpO2 group (χ2=30.44, P<0.001). Results from stepwise logistic regression analysis showed that the risk of cognitive impairment increased with each year of increased age (OR 1.07;(95%CI:1.05-1.09), P<0.001). Low SpO2, vision disorders, impaired activities of daily living, dyslipidemia, unmarried status, and lack of exercise were also associated with increased risk of cognitive impairment (OR 1.64; (95% CI: 1.11-2.43), OR 1.73; (95% CI: 1.27-2.35), OR 3.54; (95% CI: 2.62-4.79), OR 1.38; (95% CI: 1.02-1.86), OR 2.05;(95%CI:1.34-3.13), OR 1.83;(95%CI:1.13-2.97), respectively, P<0.05). Stratified analysis by age group showed that the association between SpO2 and cognitive impairment was most significant in participants aged ≥90 years (OR 1.58; (95% CI: 1.09-2.28), P=0.016). Conclusion Low oxygen saturation was associated with higher risk of cognitive impairment in our population of elderly adults.
6.Association between oxygen saturation and cognitive function in older adults from longevity areas in China
Liqin SU ; Zhaoxue YIN ; Ning XU ; Yuebin LYU ; Jiesi LUO ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2016;50(7):600-604
Objective To explore the relationship between oxygen saturation (SpO2) and cognitive function in older adults from longevity areas in China. Methods A total of 2 285 participants aged ≥65 years according to the 2012 Chinese Longitudinal Healthy Longevity Survey were included in this study. Among them, 1 739 participants aged 65-99 years were randomly selected, and 546 participants aged≥100 years were totally involved. A standardized questionaire was used to collect the information of demographic characteristics, life styles, disease history, etc. Cognitive function was evaluated using the Mini Mental State Examination Scale. Arterial oxygen saturation and heart rate were measured by pulse oximetry. Differences in cognitive function between the low SpO2 group (<0.94) and normal SpO2 group (≥0.94) were analyzed, and logistic regression models were used to analyze the relationship between SpO2 and cognitive function. Results The total score of cognitive function was 22.6 ± 9.7 for the 1 922 participants in the normal SpO2 group, and 18.8 ± 11.0 for the 363 participants in the low SpO2 group (t=6.11, P<0.001). The proportion of cognitive impairment in the low SpO2 group was 36.6% (n=133), and 22.9% (n=441) in the normal SpO2 group (χ2=30.44, P<0.001). Results from stepwise logistic regression analysis showed that the risk of cognitive impairment increased with each year of increased age (OR 1.07;(95%CI:1.05-1.09), P<0.001). Low SpO2, vision disorders, impaired activities of daily living, dyslipidemia, unmarried status, and lack of exercise were also associated with increased risk of cognitive impairment (OR 1.64; (95% CI: 1.11-2.43), OR 1.73; (95% CI: 1.27-2.35), OR 3.54; (95% CI: 2.62-4.79), OR 1.38; (95% CI: 1.02-1.86), OR 2.05;(95%CI:1.34-3.13), OR 1.83;(95%CI:1.13-2.97), respectively, P<0.05). Stratified analysis by age group showed that the association between SpO2 and cognitive impairment was most significant in participants aged ≥90 years (OR 1.58; (95% CI: 1.09-2.28), P=0.016). Conclusion Low oxygen saturation was associated with higher risk of cognitive impairment in our population of elderly adults.