Objective Study the effect of Shuxuetong combined with Shenmai injection on serum CPR, SOD and MDA levels in elderly patients with acute myocardial infarction after PCI, and to analyze the main adverse cardiovascular events. Methods Chose 88 patients with PCI from June 2015 to June 2016 in our hospital, they were randomly divided into observation group and control group, 44 cases in each group. The control group was given conventional drug therapy before PCI. On the basis of this, the observation group was treated with Shuxuetong combined with Shenmai intravenous injection before PCI. The treatment of the two groups continued to one week after PCI. Compared the levels of serum malondialdehyde (MDA), superoxide dismutase (SOD) and hypersensitive C-reactive protein (hs-CRP) between the two groups before and after PCI, and compared the levels of coagulation factor, dynamic electrocardiogram, Left ventricular ejection fraction (LVEF) and myocardial infarct size, and compared the incidence of arrhythmia and major adverse cardiovascular events after PCI. Results The levels of serum MDA and hs-CRP in the observation group were significantly lower than those in the control group (P<0.05), the level of SOD was significantly higher than the control group (P<0.05); The level of coagulation factor in the observation group was significantly higher than that in the control group (P<0.05). The myocardial infarct size, the number of ischemic attacks, the decrease of ST segment and the descending time of ST segment were significantly lower than those of the control group (P<0.01). The incidence of MACE was significantly lower in the observation group than in the control group (P<0.05). Conclusion Conventional treatment combined with Shuxuetong combined with Shenmai injection can effectively prevent ischemia-reperfusion injury in elderly patients with AMI, improve cardiac function and reduce the main adverse cardiovascular events after PCI, which reflects the combination of traditional Chinese and western medicine Advantages, worthy of clinical use.

The expression of tissue factor (TF) on the surface can be called TF positive MP, which participate not only in thrombosis, but also in the invasion and metastasis of tumors. Therefore, this article will review the role of TF positive MP in patients with malignant tumors.

Virtual reality is a technology to simulate the real world by computer, with 3 characteristics of immersion, interaction and imagination. It is a new method applied to gait rehabilitation after stroke. This article briefly introduced the characteristics of virtual reality, and the value for rehabilitation in stroke patients. The recent development of the studies on virtual reality in gait rehabilitation for stroke was summarized, mainly included the advantages of virtual reality technology, virtual reality hardware devices applied to the gait rehabilitation, and its therapeutic effect.

Objective To analyse the detective rate and significance in diagnosis of cerebral and meningeal metastases by MR.Methods 115 cases with cerebral and meningeal metastasis were proved by operation and pathology.There were male 86 and females 29 ranged in age from 17-77 years old,plain MR scan and enhanced MR scan were performed in all cases.Results In this group included 46 cerebral metastases(40.0%),33 meningeal metastasis(28.7%),36 both cerebral and meningeal metastases(31.3%). Different degree of enhancement was showed on enhanced MRI in all cases, "mouse tail signs"or"target signs" were appeared in which cerebral metastasis with the adjoining meninges involved.Conclusion MRI is a good method for diagnosing cerebral and meningeal metastasis.Enhanced MRI has an important value.

Objective To determine the ELISA cut‐off value for the diagnosis of alveolar echinococcosis by applying ROC curve . Methods 34 cases of alveolar echinococcosis specimens confirmed by the gold standard were selected and detected by ELISA .The diagnostic cut‐off value was determined by ROC curve ,and the sensitivity and specificity were calculated according to the cut‐off value .Results When the cut‐off value was 0 .44 ,the ROC curve had the largest area under the curve (AUC) accounting of 0 .995 , and the sensitivity and specificity w ere 97 .06% and 97 .06% respectively .Conclusion T he ROC curve is the best w ay to determine the cut‐off value of ELISA .

Objective To study the disease pathogenesis of systemic lupus erythematosus patients with thrombocytopenia ,and discuss reticulated platelets (RP) in SLE merger thrombocytopenia disease of diagnosis and treatment in the clinical application val-ue .Methods 55 patients diagnosed with SLE patients and 50 cases of healthy check-up ,low platelet count patients of SLE patients treated before and after the inspection by Sysmex XE-5000 automatic blood cell analyzer immature platelet fraction (IPF) and other peripheral blood cell parameters .Results Group of patients with SLE and normal controls of IPF test results respectively was (5 .30 ± 3 .75)% ,(2 .74 ± 1 .05)% ,both comparative difference was statistically significant (P<0 .05);SLE associated with throm-bocytopeniagroupofIPF[(10.14±3.66)% ],platelets(PLT)[(67.2±13.5)×109/L],meanplateletvolume(MPV)[(12.64± 0 .92)fL] ,platelet distribution width(PDW)[(18 .24 ± 1 .70)fL] compared with normal control group and SLE did not reduce plate-let group ,differences had statistical significance(P<0 .05);SLE associated with thrombocytopenia in patients with IPF respectively before and after treatment was (9 .76 ± 1 .82)% and (5 .86 ± 0 .96)% ,both comparative difference was statistically significant (P<0 . 05) .Conclusion The main cause of SLE patients with thrombocytopenia may be associated with peripheral blood platelet destruc-tion ,IPF′s result can reflect the bone marrow platelet production ,Help in the auxiliary diagnosis of disease and prognosis judg-ment .

Objective It has been known that NSAIDs can inhibit the growth of tumors through cyclooxygenase, but it is unknown that whether there are other mechanisms involved. It is essential to detect the effect of indomethacin for proliferation and apoptosis in the HCT116 and explore its anti tumor mechanism. Methods Human colon adenocarcinoma cell line HCT116 was treated with different concentration of indomethacin for 24 h and CDK 2,CDK 4, Bcl 2, Bax and p21 WAF1/CIP1 protein were detected by Western blot. Results Indomethacin down regulated the expression of CDK 2, CDK 4, Bcl 2 and up regulated the expression of p21 WAF1/CIP1 , however, the expression of Bax remained unchanged. Conclusions Inhibiting proliferation and inducing apoptosis contribute to the anti tumor activity of indomethacin by down regulating the expression of CDK 2, CDK 4, Bcl 2 and up regulating the expression of p21 WAF1/CIP1 .

Objective To determine the relation between the expression of urocortin and corticotropin-releasing hormone receptor 2? (CRH-R2?) in the placenta and pathogenesis of preeclampsia. Methods Placentas were collected from 20 pregnant women with preeclampsia as study group and 20 normal pregnant women as control group. Urocortin mRNA and CRH-R2? mRNA were measured by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR). Urocortin peptide was measured by immunohistochemistry. Results (1) The mRNA expression of urocortin was significantly higher (P

Objective To investigate the difference in complete blood count (CBC) within the defined time among 28 hospitals with different grade in Urumchi City, explore its influencing factors,offer the countermeasures, and further to provide scientific evidence for the mutual recognition among different medical institutions. Methods Totally 28 laboratories with different grade were enrolled in the investigation. Three fresh blood samples were employed to perform complete blood counting, in-cluding normal and pathological specimens. The measuring time and turn around time (TAT) were de-fined. Results According to the literature report on biological variability of testing results, the per-missible deviation of CBC was tentatively prescribed as follows: WBC 15% ;RBC 6% ;HB 7% ;HCT 6 % ;PLT 25 %. Qualification decision was based on the external quality assessment (EQA) criteria of Clinical Laboratory Centre of the Health Ministry. Qualification: the total score of five measured items is higher than or equal to 80%;disqualification: the total score of five measured items is lower than 80%. For the first and second sample, 26 laboratories (92.86%) were qualified;for the third sample (only 21 laboratories enrolled), 14 laboratories (67%) were qualified. Conclusion 28 laboratories par-ticipated in this test. The results of five items are congruent for the first and second sample (normalspecimens) in 28 laboratories, and the measured results are comparable. By contrast, the comparative result is unsatisfactory for the third sample (pathological specimen), mainly due to the narrow linear range of equipment. Meanwhile, the laboratory quality management should be strengthened.

Objective To understand the situation of nosocomial infections, the distribution of important pathogens of affected patients and the uses of antibacterial drugs.Methods The cross-sectional survey was ap-plied.Before the survey, the investigators were trained by the professionals of the department of hospital infection management.Medical records were reviewed one by one, checked with bedside physical examination.Results In this survey, 283 inpatients were investigated, with an actual check rate of 100%.Two inpatients were affected with nosocomial infection with the prevalence rate of 0.71%.There were two cases of infections (0.71%).Conclusion Investigation of the prevalence rate of nosocomial infection was an important means to monitor the hospital infection, which can monitor specifically, minimize the incidence of nosocomial infection and ensure medical safety by obtaining the information of the departments with high-risk nosocomial infection, the main infectious sites and pathogens.